Abstract: An expandable clot mobilizer device for extraction of an occlusion from a blood vessel is provided, which comprises a working portion including a plurality of crowns of cells. Each cell comprises an open area bordered by two proximal cell struts, two distal cell struts, and two middle cell struts. The proximal cell struts each extending distally from a common proximal end to a proximal end of a respective one of the two middle cell struts, the distal cell struts each extending proximally from a common distal end to a distal end of a respective one of the two middle cell struts, each middle cell strut in each crown bordering two adjacent cells in that crown and each middle cell strut being adapted and configured to be more flexible than the distal cell strut and the proximal cell strut to which it extends. The clot mobilizer also comprises a tapered portion.

Abstract: A self-expandable medical device for advancement through vasculature to an expansion site in a blood vessel is disclosed. The device comprises a working portion and a connection portion that can be connected to a pusher. The working portion provides an outward radial force at every diameter between and including the diameter of a compressed and an expanded configurations, and comprises a plurality of crowns of cells comprising an open area bordered by two proximal cell struts, two distal cell struts, and two middle cell struts. The proximal cell struts each extend distally from a common proximal end to a proximal end of a respective one of the two middle cell struts. The distal cell struts each extend proximally from a common distal end to a distal end of a respective one of the two middle cell struts. Each middle cell strut is more flexible than the distal cell strut and proximal cell strut to which it extends.

Abstract: Method for generating and controlling complex strain patterns on biological materials comprising the steps of providing a magnetic stimulation device and a magneto-responsive substrate; culturing biological material in the substrate; determining the position of the magnetic stimulation device for obtaining a defined strain pattern on the biological material; placing the magnets in the position determined; and activating a magnetic stimulation device to generate a complex strain pattern in the magneto-responsive substrate and consequently in the biological material; and magneto-mechanical stimulation system comprising a magneto-responsive substrate configured to hold biological material; a holder for placing the magneto-responsive substrate; a magnetic stimulation device configured to generate a complex strain pattern on the biological material by generating a magnetic field which acts over the magneto-responsive substrate; a computing module; an imaging module for long-term monitoring; and an interface module