Patents by Inventor Daniel Garrido

Daniel Garrido has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzymes and methods for cleaving n-glycans from glycoproteins
    Patent number: 11633461
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Grant
    Filed: April 16, 2021
    Date of Patent: April 25, 2023
    Assignee: The Regents of the University of California
    Inventors: Daniel Garrido, J. Bruce German, Carlito B. Lebrilla, David A. Mills
  • ENZYMES AND METHODS FOR CLEAVING N-GLYCANS FROM GLYCOPROTEINS
    Publication number: 20210308235
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Application
    Filed: April 16, 2021
    Publication date: October 7, 2021
    Inventors: Daniel GARRIDO, J. Bruce GERMAN, Carlito B. LEBRILLA, David A. MILLS
  • Enzymes and methods for cleaving n-glycans from glycoproteins
    Patent number: 11000576
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: May 11, 2021
    Assignee: The Regents of the University of California
    Inventors: Daniel Garrido, J. Bruce German, Garlito B. Lebrilla, David A. Mills
  • ENZYMES AND METHODS FOR CLEAVING N-GLYCANS FROM GLYCOPROTEINS
    Publication number: 20200345818
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Application
    Filed: May 11, 2020
    Publication date: November 5, 2020
    Inventors: Daniel GARRIDO, J. Bruce GERMAN, Carlito B. LEBRILLA, David A. MILLS
  • Enzymes and methods for cleaving N-glycans from glycoproteins
    Patent number: 10688160
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: June 23, 2020
    Assignee: The Regents of the University of California
    Inventors: Daniel Garrido, J. Bruce German, Carlito B. Lebrilla, David A. Mills
  • Enzymes and methods for cleaving N-glycans from glycoproteins
    Patent number: 10639357
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: May 5, 2020
    Assignee: The Regents of the University of California
    Inventors: Daniel Garrido, J. Bruce German, Carlito B. Lebrilla, David A. Mills
  • ENZYMES AND METHODS FOR CLEAVING N-GLYCANS FROM GLYCOPROTEINS
    Publication number: 20200030418
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Application
    Filed: September 3, 2019
    Publication date: January 30, 2020
    Inventors: Daniel GARRIDO, J. Bruce GERMAN, Carlito B. LEBRILLA, David A. MILLS
  • ENZYMES AND METHODS FOR CLEAVING N-GLYCANS FROM GLYCOPROTEINS
    Publication number: 20190381150
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Application
    Filed: September 3, 2019
    Publication date: December 19, 2019
    Inventors: Daniel GARRIDO, J. Bruce GERMAN, Carlito B. LEBRILLA, David A. MILLS
  • Enzymes and methods for cleaving N-glycans from glycoproteins
    Patent number: 10471134
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: November 12, 2019
    Assignee: The Regents of the University of California
    Inventors: Daniel Garrido, J. Bruce German, Carlito B. Lebrilla, David A. Mills
  • Enzymes And Methods For Cleaving N-Glycans From Glycoproteins
    Publication number: 20190054155
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Application
    Filed: August 8, 2018
    Publication date: February 21, 2019
    Inventors: Daniel GARRIDO, J. Bruce GERMAN, Carlito B. LEBRILLA, David A. MILLS
  • Methods and compositions for improved digestion of milk oligosaccharides
    Patent number: 10165788
    Abstract: Pre-biotic compositions containing oligosaccharides and probiotic compositions useful for treatment of a subject are provided herein. Also provided are methods for administering probiotic or pre-biotic compositions.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: January 1, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: David Mills, Daniel Garrido, Santiago Ruiz-Moyano, Carlito Lebrilla, J. Bruce German
  • Enzymes and methods for cleaving N-glycans from glycoproteins
    Patent number: 10071142
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: September 11, 2018
    Assignee: The Regents of the University of California
    Inventors: Daniel Garrido, J. Bruce German, Carlito B. Lebrilla, David A. Mills
  • ENZYMES AND METHODS FOR CLEAVING N-GLYCANS FROM GLYCOPROTEINS
    Publication number: 20160287680
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Application
    Filed: March 24, 2016
    Publication date: October 6, 2016
    Inventors: Daniel Garrido, J. Bruce German, Carlito B. Lebrilla, David A. Mills
  • Enzymes and methods for cleaving N-glycans from glycoproteins
    Patent number: 9327016
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: May 3, 2016
    Assignee: The Regents of the University of California
    Inventors: Daniel Garrido, J. Bruce German, Carlito B. Lebrilla, David A. Mills
  • ENZYMES AND METHODS FOR CLEAVING N-GLYCANS FROM GLYCOPROTEINS
    Publication number: 20150110771
    Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.
    Type: Application
    Filed: February 14, 2013
    Publication date: April 23, 2015
    Inventors: Daniel Garrido, J. Bruce German, Carlito B. Lebrilla, David A. Mills
  • Methods and Compositions for Improved Digestion of Milk Oligosaccharides
    Publication number: 20150010670
    Abstract: Pre-biotic compositions containing oligosaccharides and probiotic compositions useful for treatment of a subject are provided herein. Also provided are methods for administering probiotic or pre-biotic compositions.
    Type: Application
    Filed: June 16, 2014
    Publication date: January 8, 2015
    Inventors: David Mills, Daniel Garrido, Santiago Ruiz-Moyano, Carlito Lebrilla, J. Bruce German