Abstract: A micro-nozzle with an integrated filter structure for receiving fluids at pressures between 0.1 MPa to 50 MPa, comprising: at least one fluid inlet, a fluid outlet comprising at least one orifice, a primary filter structure positioned downstream from the at least one fluid inlet and arranged to provide statistical filtration of fluid passing therethrough.

Abstract: An apparatus is provided for nebulising a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus comprises an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling means, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various means for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.

Abstract: An apparatus is provided for nebulising a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus comprises an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling means, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various means for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.

Abstract: An apparatus is provided for nebulizing a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus includes an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling mechanism, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various mechanisms for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.

Abstract: A spray device for generating a slow moving aerosol, whereby the aerosol is generated from at least two impinging jets and the jets are formed by forcing liquid through a single moulded plastic nozzle assembly comprising: a. one or more thin walled sections (typically <200 ?m) (18) where the thin wall sections (18) are supported by one or more thick walled sections (typically >200 ?m) (17, 19). b. at least two opposing holes (13) with hydraulic diameters of 5 pm to 100 ?m (typically 30 ?m) and axes at an angle of between 55 and 125 degrees (preferably 90 degrees) to an external surface of the thin walled section (18), such that the projected areas of the holes (13) at least partially intersect at the outlet side of the nozzle.

Abstract: A spray device for generating an aerosol of a liquid such as a medicament. The device includes a perforate element comprising one or more nozzles, each nozzle having an inlet and an outlet. A drive mechanism causes, in use, liquid to be driven through the one or more nozzles, thereby forming a liquid spray having one or more streams of liquid. At least one impaction surface is provided onto which, in use, the liquid impacts, the impaction surface being located downstream of the nozzle outlet(s).

Abstract: An apparatus is provided for nebulising a liquid from a liquid supply through a membrane comprising first and second surfaces and a plurality of apertures extending through the membrane. The apparatus includes an area for receiving a liquid supply, arranged to deliver a liquid to the first surface of the membrane, a vibrator member, arranged to vibrate the membrane to eject liquid droplets from the front surface of the membrane on vibration; and a mechanical coupling mechanism, arranged to provide a removable mechanical clamping force for clamping the membrane to the vibrator member. Various mechanisms for implementing the mechanical coupling are provided, and liquid containers and membranes for use in the device are proposed.