Abstract: The present disclosure relates to novel compounds that are capable of inhibiting the mitochondrial pyruvate carrier and promoting hair growth. The disclosure further relates to methods of promoting hair growth or treating conditions or disorders affecting hair growth, such as baldness or alopecia.

Abstract: A sterilization system uses ultraviolet radiation and ozone to eradicate deadly pathogens to sterilize a surface of an object or wound/incision site at an adjustable intensity level. The sterilization system has ultraviolet emitters that emit ultraviolet light in wavelengths that kill pathogens and in wavelengths that produce ozone at the sites, therefore killing/disabling several hard-to-kill pathogens. The sterilization system has an intensity control and proximity detectors to enable ultraviolet emission only when the system is properly located near or against the surface so as to protect from unwanted radiation from the ultraviolet light.

Abstract: The present invention is related to topical ophthalmic compositions comprising brimonidine. Also described herein are methods for the treatment of ocular conditions (e.g., presbyopia), methods for improving near reading speed in a subject with presbyopia, methods for improving near vision in a subject with presbyopia, and methods for reducing pupil diameter in a subject with presbyopia using the topical ophthalmic compositions.

Abstract: A sterilization system uses ultraviolet radiation and ozone to eradicate deadly pathogens to sterilize a surface of an object or wound/incision site at an adjustable intensity level. The sterilization system has ultraviolet emitters that emit ultraviolet light in wavelengths that kill pathogens and in wavelengths that produce ozone at the sites, therefore killing/disabling several hard-to-kill pathogens. The sterilization system has an intensity control and proximity detectors to enable ultraviolet emission only when the system is properly located near or against the surface so as to protect from unwanted radiation from the ultraviolet light.

Abstract: A sterilization system uses ultraviolet radiation and ozone to eradicate deadly pathogens to sterilize a zone of a surface of an object or wound/incision sites. The sterilization system offers a safe sterilization method prior to or after surgery and/or closure wounds/incisions. The sterilization system has ultraviolet emitters that emit ultraviolet light in wavelengths that kill pathogens and in wavelengths that produce ozone at the sites, therefore killing/disabling several hard-to-kill pathogens. The sterilization system has proximity detectors to enable ultraviolet emission only when the system is properly located near or against the surface so as to protect from unwanted radiation from the ultraviolet light.

Abstract: A sterilization system uses ultraviolet radiation and ozone to eradicate deadly pathogens to sterilize a zone of a surface of an object or wound/incision sites. The sterilization system offers a safe sterilization method prior to or after surgery and/or closure wounds/incisions. The sterilization system has ultraviolet emitters that emit ultraviolet light in wavelengths that kill pathogens and in wavelengths that produce ozone at the sites, therefore killing/disabling several hard-to-kill pathogens. The sterilization system has proximity detectors to enable ultraviolet emission only when the system is properly located near or against the surface so as to protect from unwanted radiation from the ultraviolet light.

Abstract: A sterilization system uses ultraviolet radiation and ozone to eradicate deadly pathogens to sterilize wound/incision sites. The sterilization system offers a safe sterilization method prior to or after surgery and/or closure wounds/incisions. The sterilization system has ultraviolet emitters that emit ultraviolet light in wavelengths that kill pathogens and in wavelengths that produce ozone at the sites, therefore killing/disabling several hard-to-kill pathogens. The sterilization system has surface detectors to enable ultraviolet emission only when the system is properly seated against the skin so as to protect from unwanted radiation from the ultraviolet light.

Abstract: A sterilization system uses ultraviolet radiation and ozone to eradicate deadly pathogens to sterilize wound/incision sites. The sterilization system offers a safe sterilization method prior to or after surgery and/or closure wounds/incisions. The sterilization system has ultraviolet emitters that emit ultraviolet light in wavelengths that kill pathogens and in wavelengths that produce ozone at the sites, therefore killing/disabling several hard-to-kill pathogens. The sterilization system has surface detectors to enable ultraviolet emission only when the system is properly seated against the skin so as to protect from unwanted radiation from the ultraviolet light.

Abstract: Composite fibers and methods of manufacturing composite fibers for the reinforcement of concrete are provided. The composite fibers include fibers and a polymeric coating. The composite fibers have a length of about 10 mm to about 80 mm and an equivalent diameter from about 0.3 mm to about 2 mm. A method for reinforcing concrete using the composite fibers is further provided.

Abstract: Methods for treating, reducing the occurrence or preventing a histamine-independent pruritic itch using a clostridial toxin derivative are provided herein. In some aspects, the clostridial toxin derivative reduces the itch intensity or duration without affecting thermal or pain sensitivity.

Abstract: Composite fibers and methods of manufacturing composite fibers for the reinforcement of concrete are provided. The composite fibers include fibers and a polymeric coating. The composite fibers have a length of about 10 mm to about 80 mm and an equivalent diameter from about 0.3 mm to about 2 mm. A method for reinforcing concrete using the composite fibers is further provided.

Abstract: Composite fibers and methods of manufacturing composite fibers for the reinforcement of concrete are provided. The composite fibers include fibers and a polymeric coating. The composite fibers have a length of about 10 to about 80 mm and an equivalent diameter from about 0.3 to about 2 mm. A method for reinforcing concrete using the composite fibers is further provided.

Abstract: An object sterilization system includes an enclosure having an access door with at least one ultraviolet emitting device supported within the enclosure. The ultraviolet emitting device(s) are for directing ultraviolet radiation on an object placed within the enclosure. A source of power is interfaced to each of the at least one ultraviolet emitting devices, operatively flowing current through each of the at least one ultraviolet emitting devices, thereby each of the at least one ultraviolet emitting device emits ultraviolet radiation for producing ozone and for sterilizing the object.

Abstract: The present invention relates to, a sizing composition for reinforcing glass fiber strands, which comprises a silane coupling agent, a polyurethane film-forming agent including a blocked isocyanate and water. The invention also relates to glass fiber strands onto which the sizing composition has been applied, and to concrete reinforced with said glass fiber strands.

Abstract: A foot/shoe sanitizing system includes a housing having at least one opening and at least one ultraviolet emitting device supported within the housing. The ultraviolet emitting devices direct ultraviolet light around and/or through the set of foot/shoe support bars towards the foot or shoe placed on the foot/shoe support bars. The ultraviolet emitting devices are controllably powered to emit ultraviolet light and/or ozone onto the foot/shoe. In a preferred embodiment, the ultraviolet emitting device emits light that includes short wavelength ultraviolet light, causing the formation of ozone in the area of the shoe, thereby killing pathogens that are not easily killed with ultraviolet light alone. The system includes a sheet of activated carbon for catalyzing the ozone into harmless concentrations of carbon monoxide and carbon dioxide.

Abstract: A foot/shoe sanitizing system includes a housing having at least one opening and at least one ultraviolet emitting device supported within the housing. The ultraviolet emitting devices direct ultraviolet light around and/or through the set of foot/shoe support bars towards the foot or shoe placed on the foot/shoe support bars. The ultraviolet emitting devices are controllably powered to emit ultraviolet light and/or ozone onto the foot/shoe. In a preferred embodiment, the ultraviolet emitting device emits light that includes short wavelength ultraviolet light, causing the formation of ozone in the area of the shoe, thereby killing pathogens that are not easily killed with ultraviolet light alone. The system includes a sheet of activated carbon for catalyzing the ozone into harmless concentrations of carbon monoxide and carbon dioxide.

Abstract: A foot/shoe sanitizing system includes a housing having at least one opening and at least one ultraviolet emitting device supported within the housing. The ultraviolet emitting devices direct ultraviolet light around and/or through the set of foot/shoe support bars towards the foot or shoe placed on the foot/shoe support bars. The ultraviolet emitting devices are controllably powered to emit ultraviolet light and/or ozone onto the foot/shoe. In a preferred embodiment, the ultraviolet emitting device emits light that includes short wavelength ultraviolet light, causing the formation of ozone in the area of the shoe, thereby killing pathogens that are not easily killed with ultraviolet light alone. The system detects the identity of a user and records/transmits usage of the system by the user for sanitizing enforcement and recording.

Abstract: A foot/shoe sanitizing system includes a housing having at least one opening and a set of foot/shoe support bars coupled to the housing in proximity to the at least one opening. The foot/shoe support bars support a foot or shoe placed through the opening(s). At least one ultraviolet emitting device is supported within the housing beneath the set of foot/shoe support bars. The ultraviolet emitting devices direct ultraviolet light around and/or through the set of foot/shoe support bars towards the foot or shoe placed on the foot/shoe support bars. The ultraviolet emitting devices are controllably powered by a source of power to emit ultraviolet light. In a preferred embodiment, the ultraviolet emitting device emits light that includes short wavelength ultraviolet light, causing the formation of ozone in the area of the shoe, thereby killing pathogens that are not easily killed with ultraviolet light alone.

Abstract: A foot/shoe sanitizing system includes a housing having at least one opening and at least one ultraviolet emitting device supported within the housing. The ultraviolet emitting devices direct ultraviolet light around and/or through the set of foot/shoe support bars towards the foot or shoe placed on the foot/shoe support bars. The ultraviolet emitting devices are controllably powered to emit ultraviolet light and/or ozone onto the foot/shoe. In a preferred embodiment, the ultraviolet emitting device emits light that includes short wavelength ultraviolet light, causing the formation of ozone in the area of the shoe, thereby killing pathogens that are not easily killed with ultraviolet light alone. The system detects the identity of a user and records/transmits usage of the system by the user for sanitizing enforcement and recording.

Abstract: Compounds of Formula 1 where X is S and the variables have the meaning defined in the specification are specific or selective to alpha2B and/or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such have no or only minimal cardiovascular and/or sedatory activity. These compounds of Formula 1 are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors. Compounds of Formula 1 where X is O also have the advantageous property that they have no or only minimal cardiovascular and/or sedatory activity and are useful for treating pain and other conditions with no or only minimal cardiovascular and/or sedatory activity.