Abstract: Provided herein are methods, systems, and compositions for degrading minerals. The methods, systems, and compositions provided herein involve the use of enzymes having silicase activity and an increased ability to degrade minerals such as silicate materials. The methods, systems, and compositions provided herein may be used to release metal from the amorphous silica. The methods, systems, and compositions provided herein may further involve collecting, extracting, and/or purifying the metal released from the minerals.

Abstract: A catheter has a two-piece tip electrode with a shell and a support structure that are secured to each other by multiple redundant mechanisms in order to reduce the risk of tip detachment during a procedure. The tip electrode includes at least two different welds attaching the shell to the support structure to provide a dual failure mode. One weld includes a seam weld and another weld includes a penetration weld.

Abstract: A method for detecting an electrical fault in an electrical installation includes: measuring an alternating electric current flowing through the electrical installation; detecting an electrical fault on the basis of the measured electric current; and tripping the electrical protection device when an electrical fault is identified by the electronic control device. The detection of the fault includes identifying a transition of the measured current from a first level to a second level with a duration lower than a predefined threshold which is lower than or equal to 10% of the nominal period of the alternating electric current, the first level and the second level corresponding to current values of opposite sign but the amplitude of which, in terms of absolute value, is higher than a predefined current threshold equal to the product of the trip threshold of the protection device and a weighting coefficient.

Abstract: HSP110 inhibitors bind directly to the nucleotide binding domain of HSP110 and then block the phosphorylation of STAT3, cancer cell growth or MyD88 stability. Aspects involve a compound of formula (I) for use in the treatment of a HSP110-associated cancer, for example colorectal cancer and lymphoma. An examplary compound was tested on a syngeneic model for which mouse colon cancer CT-26 cells were injected into Balb/c mice and on a NOD/SCID model in which mice were implanted with human colorectal cancer HCT116 cells. In those animals bearing a tumor, the compound induced tumor regression that was associated with the inhibition of other HSP110 reported tumorigenic functions (resistance to apoptosis, induction of pro-tumor macrophages). Further, the compound was tested on large B cell lymphoma cell lines (DLBCL) and it was able to alter the interaction between HSP110 and MyD88, which induces a degradation of the oncogene MyD88.

Abstract: Systems, methods, and computer-readable mediums include detecting and eliminating a three-phase without neutral short-circuit in a load supplied by a power converter. After detecting the short circuit, the current at an output conductor for one of the three-phases is stopped and then resumed after a sufficient amount of current causes a downstream protection device of the faulty load to trip.

Abstract: Systems, methods, and apparatuses disclosed herein standardize product views of product images in the product catalog such that these products are displayed with substantially similar products views with respect to one another in the product catalog to enhance the visual appearance, or photorealism, of the product catalog. As such, the products within the same category of products, for example, the screws and bolts as described above, are illustrated in the product catalog with similar product views, for example, similar orientations, similar scales, and/or similar angles, with respect to one another.

Abstract: A catheter has a two-piece tip electrode with a shell and a support structure that are secured to each other by multiple redundant mechanisms in order to reduce the risk of tip detachment during a procedure. The tip electrode includes at least two different welds attaching the shell to the support structure to provide a dual failure mode. One weld includes a seam weld and another weld includes a penetration weld.

Abstract: A catheter has a two-piece tip electrode with a shell and a support structure that are secured to each other by multiple redundant mechanisms in order to reduce the risk of tip detachment during a procedure. The tip electrode includes at least two different welds attaching the shell to the support structure to provide a dual failure mode. One weld includes a seam weld and another weld includes a penetration weld.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for assisting an agent in providing support to a customer. The methods, systems, and apparatus include actions of obtaining interaction information regarding an interaction between a customer and an agent, identifying the customer from the interaction information, aggregating the information regarding the customer from multiple sources, determining an intent of the customer from the interaction information and the aggregated information, determining a sentiment of a customer from the interaction information and the aggregated information, determining a particular action to indicate to the agent based on the aggregated information, the intent, and the sentiment, and generating an interface to provide the agent based at least on the particular action.

Abstract: An electrical protection method for detecting an electrical fault in an electrical installation includes: measuring electrical variables by way of an auxiliary protection device, the electrical variables being associated with phase conductors; automatically analysing the measured electrical variables in order to identify a condition representative of a short circuit between phase conductors; detecting an electrical fault, such as a short circuit between the three electrical phases associated with the phase conductors without any neutral conductor involved, based on the measured electrical variables; triggering the opening of a switching device of the auxiliary protection device when an electrical fault is identified in order to disconnect one of the phase conductors, the switching device being connected to one of the phase conductors.

Abstract: A method for detecting an electrical fault in an electrical installation comprises steps of includes: measuring an alternating electric current flowing through the electrical installation; detecting an electrical fault on the basis of the measured electric current; and tripping the electrical protection device when an electrical fault is identified by the electronic control device. The detection of the fault includes identifying a transition of the measured current from a first level to a second level with a duration lower than a predefined threshold which is lower than or equal to 10% of the nominal period of the alternating electric current, the first level and the second level corresponding to current values of opposite sign but the amplitude of which, in terms of absolute value, is higher than a predefined current threshold equal to the product of the trip threshold of the protection device and a weighting coefficient.

Abstract: Systems, methods, and computer-readable mediums include detecting and eliminating a three-phase without neutral short-circuit in a load supplied by a power converter. After detecting the short circuit, the current at an output conductor for one of the three-phases is stopped and then resumed after a sufficient amount of current causes a downstream protection device of the faulty load to trip.

Abstract: Systems, methods, and computer-readable mediums include detecting and eliminating a three-phase without neutral short-circuit in a load supplied by a power converter. After detecting the short circuit, the current at an output conductor for one of the three-phases is stopped and then resumed after a sufficient amount of current causes a downstream protection device of the faulty load to trip.

Abstract: Systems, methods, and computer-readable mediums include detecting and eliminating a three-phase without neutral short-circuit in a load supplied by a power converter. After detecting the short circuit, the current at an output conductor for one of the three-phases is stopped and then resumed after a sufficient amount of current causes a downstream protection device of the faulty load to trip.

Abstract: HSP110 is involved in multiple tumorigenic processes but no inhibitor was known to date. The inventors have identified for the first time HSP110 inhibitors. These inhibitors bind directly to the nucleotide binding domain of HSP110 and then blocks the phosphorylation of STAT3, cancer cell growth or MyD88 stability. The present invention relates to a compound of general formula (I) for use in the treatment of a HSP 110-associated cancer, for example colorectal cancer and lymphoma. Especially the inventors tested the compound on two different colorectal mice models, a syngeneic model for which mouse colon cancer CT-26 cells were injected into Balb/c mice and a NOD/SCID model in which mice were implanted with human colorectal cancer HCT116 cells. In those animals bearing a tumor, the compound induced tumor regression that was associated with the inhibition of other HSP110 reported tumorigenic functions (resistance to apoptosis, induction of pro-tumor macrophages).

Abstract: A catheter has a two-piece tip electrode with a shell and a support structure that are secured to each other by multiple redundant mechanisms in order to reduce the risk of tip detachment during a procedure. The tip electrode includes at least two different welds attaching the shell to the support structure to provide a dual failure mode. One weld includes a seam weld and another weld includes a penetration weld.

Abstract: An apparatus includes a fluid bag support coupling, a signal generating assembly, and a signal output driver circuit. The fluid bag support coupling is configured to support a fluid source. The signal generating assembly is configured to generate a signal in response to an amount of fluid within the fluid source. The signal output driver circuit is in electrical communication with the signal generating assembly. The signal output driver circuit is configured to transmit the signal from the signal generating assembly to a working element configured to perform a task. The signal is configured to inhibit the working element from performing the task when the amount of fluid within the fluid source reaches a predetermined threshold amount.

Abstract: A catheter has a two-piece tip electrode with a shell and a support structure that are secured to each other by multiple redundant mechanisms in order to reduce the risk of tip detachment during a procedure. The tip electrode includes at least two different welds attaching the shell to the support structure to provide a dual failure mode. One weld includes a seam weld and another weld includes a penetration weld.

Abstract: A mapping system, computer program product and method provide visualization of the dynamic range of an aircraft. A method may include: receiving map data, where the map data includes a three-dimensional terrain map of a geographic region; determining a location of an aerial vehicle; calculating a plurality of points in a plurality of different direction that can be reached by the aerial vehicle within at least two predetermined increments of energy consumption; and providing for display of a map of the geographic region including an isoline through the plurality of points for each of the at least two predetermined increments of energy consumption representing a dynamic range of the aerial vehicle for the at least two predetermined increments of energy consumption.

Abstract: According to aspects, embodiments herein provide a power system comprising a first Uninterruptible Power Supply (UPS) configured to operate in parallel with a plurality of UPSs, the first UPS including an input configured to receive input power, an output configured to provide output power to a load, a bypass circuit interposed between the input and output and including a bypass switch, the bypass switch positioned to couple the input and the output in a bypass mode and decouple the input and the output in an on-line mode, and a controller coupled to the first UPS and configured to monitor an input current through the bypass circuit, and control the bypass switch of the first UPS to interrupt the input current through the bypass circuit of the first UPS for a delay during the bypass mode such that each UPS provides a balanced output current to the load.