Patents by Inventor Daniel Guerrier

Daniel Guerrier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Butyric acid derivatives
    Publication number: 20050020651
    Abstract: The present invention relates to a compound of the formula I: (Formula I) in which: A, B, R1, Z, n and R2 are as defined in claim 1. These compounds are useful in the treatment of dyslipidaemia, atherosclerosis and diabetes.
    Type: Application
    Filed: July 3, 2002
    Publication date: January 27, 2005
    Inventors: Didier Roche, Jean-Jacques Zeiller, Francis Contard, Valerie Guyard-Dangremont, Daniel Guerrier, Herve Dupont, Jean-Jacques Berthelon
  • Nitroso diphenylamine derivatives
    Publication number: 20040063783
    Abstract: The present invention relates to a compound of formula (I) in which X, A, T, Y, G and R are as defined in Claim (1).
    Type: Application
    Filed: April 3, 2003
    Publication date: April 1, 2004
    Inventors: Claude Lardy, Jean-Yves Nioche, Lidia Caputo, Jacques Decerprit, Jean-Yves Ortholand, Didier Festal, Daniel Guerrier
  • 4-(biphenylcarbonylamino)piperidine derivatives as mtp inhibitors
    Publication number: 20040034028
    Abstract: The present invention relates to compounds of the formula (I): in which: Z represents biphenyl optionally substitute in position 2′, 3′, 4′, 5′ and 6′ with one or more substitutents chosen from trihalomethyl and trihalomethoxy; Het represents quinolyl, quinoxalyl or pyridyl optionally substituted with one or more substitutents chosen from halo, cyano, nitro, (C1-C6)alkyl, (C6-C12)aryl, (C1-C6)alkoxy, hydroxyl, (C1-C6)thioalkoxy, carboxyl and (C1-C6)alkoxycarbonyl, or pharmaceutically acceptable salts thereof. These compounds are useful as inhibitors of microsomal triglyceride transfer protein and as inhibitors of the secretion of B apoproteins.
    Type: Application
    Filed: May 22, 2003
    Publication date: February 19, 2004
    Inventors: Alyx-Caroline Guevel, Didier Festal, Francois Collonges, Daniel Guerrier, Olivier Chevreuil
  • Benzopyrans and benzoxepines, pharmaceutical compositions comprising them and preparation process
    Patent number: 6596758
    Abstract: The present invention relates to benzopyrans and benzoxepines of formula (I), wherein X, A, R1, R2 and (R)p have the meanings as given in claim 1, which can be used in the treatment of dislipidaemias, atherosclerosis and diabetes, to pharmaceutical compositions comprising them and to processes allowing the preparation of these compounds.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: July 22, 2003
    Assignee: Merck Patent GmbH
    Inventors: Michel Brunet, Jean-Jaques Zeiller, Jean-Jaques Berthelon, Francis Contard, Guy Augert, Daniel Guerrier
  • Cyclic compounds useful in the treatment of dyslipidaemia, atherosclerosis and diabetes, pharamaceutical compositions and preparation process
    Patent number: 6528538
    Abstract: The present invention relates to cyclic compounds which are of the class of compounds of formula I wherein X and Y represent an oxygen atom and to processes for preparing such compounds. The compounds are useful in the treatment of dyslipidemia, atherosclerosis, and diabetes.
    Type: Grant
    Filed: January 16, 2001
    Date of Patent: March 4, 2003
    Assignee: Merck Patentgesellschaft
    Inventors: Jean-Jacques Zeiller, Jean-Jacques Berthelon, Eric Raspé, Daniel Guerrier
  • Benzocycloheptenes
    Patent number: 5652252
    Abstract: The subject of the invention is compounds of general formula: ##STR1## in which: X represents O or CHR,R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which are identical or different, represent a hydrogen atom or a C.sub.1 -C.sub.7 alkyl group, it being possible for R.sub.1 to additionally form a bond with R;R.sub.5 represents a hydrogen atom, a hydroxyl group or R.sub.5, taken together with R.sub.7, forms a bond or a>O; group;R.sub.6 represents a group of formula: ##STR2## in which R.sub.10 and R.sub.11, taken together with the carbon atom to which they are attached, form a nitrogenous heterocyclic group,and their N-oxides and pharmaceutically acceptable salts.These compounds are powerful activators of potassium channels.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: July 29, 1997
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Jean Jacques Berthelon, Michel Brunet, Marc Noblet, Philippe Durbin, Daniel Guerrier, Trong Nghia Luong
  • Benzoxepines
    Patent number: 5602152
    Abstract: The subject of the invention is compounds of general formula: ##STR1## in which: X represents O or CHR,R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which are identical or different, represent a hydrogen atom or a C.sub.1 -C.sub.7 alkyl group, it being possible for R.sub.1 to additionally form a bond with R;R.sub.5 represents a hydrogen atom, a hydroxyl group or R.sub.5, taken together with R.sub.7, forms a bond or a >O; group;R.sub.6 represents a group of formula: ##STR2## in which R.sub.10 and R.sub.11, taken together with the carbon atom to which they are attached, form a nitrogenous heterocyclic group, and their N-oxides and pharmaceutically acceptable salts. These compounds are powerful activators of potassium channels.
    Type: Grant
    Filed: August 5, 1994
    Date of Patent: February 11, 1997
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Jean J. Berthelon, Michel Brunet, Marc Noblet, Philippe Durbin, Daniel Guerrier, Trong N. Luong
  • 3,4-dihydro-4-oxo-3-(2-propenyl)-1-phthalazineacetic acids and derivatives, their preparations and medicines containing them
    Patent number: 5489592
    Abstract: Novel 3,4-dihydro-4-oxo-3(prop-2-enyl)-1-phtalazineacetic acids and derivatives of formula (I) ##STR1## in which R.sub.1 R.sub.2 and R.sub.3 are the same or different and stand for H, a halogen or a linear or branched aliphatic, saturated or unsaturated radical, substituted or not by at least one halogen or R.sub.4 residue such as defined below, except when R.sub.4 is H; R.sub.4 and R.sub.5 are the same or different and stand for H, a linear or branched aliphatic radical, saturated or unsaturated, an aryl or heteroaryl radical, said radicals being substituted or not by at least one grouping such as fluorine, chlorine, bromine, methyl or trifluoromethyl, where R.sub.4 and R.sub.5 do not simultaneously denote H; R.sub.6 stands for hydroxy or alkoxy radical; R.sub.
    Type: Grant
    Filed: June 20, 1994
    Date of Patent: February 6, 1996
    Assignee: Lipha, Lyonnaise Industrielle Pharmaceutique
    Inventors: Francois Collonges, Herve Dumas, Philippe Durbin, Daniel Guerrier
  • Substituted sulfonamides, process of preparation and medicines containing same
    Patent number: 5476846
    Abstract: The present invention concerns new substituted sulfonamides, and the physiologically acceptable salts, complexes, esters and amides thereof, represented by the formula ##STR1## which is defined herein. Said compounds find application as anti-thrombotic and anti-asthmatic medicines.
    Type: Grant
    Filed: November 17, 1994
    Date of Patent: December 19, 1995
    Assignee: Lipha, Lyonnaise Industrielle Pharmaceutique
    Inventors: Claude Lardy, Daniel Guerrier, Gilles Chavernac, Francois Collonges
  • Substituted sulfonamides, process of preparation and medicines containing same
    Patent number: 5387709
    Abstract: The present invention concerns new substituted sulfonamides, and the physiologically acceptable salts possibly in the form of complexes, esters and amides thereof, represented by the formula: ##STR1##
    Type: Grant
    Filed: October 12, 1993
    Date of Patent: February 7, 1995
    Assignee: Lipha Lyonnaise Industrielle Pharmaceutique
    Inventors: Claude Lardy, Daniel Guerrier, Gilles Chavernac, Francois Collonges