Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include a collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers. The collapsible scaffold may include portions of differing radial stiffness based on location of the one or more impellers therein.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include an collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.

Abstract: Catheter blood pump positioning techniques, methods, and algorithms are described. In one embodiment, pressure sensor measurements are used to determine the distance to the aortic valve and the left ventricle. An optimal positioning location can be determined based on the pressure sensor measurements. The catheter blood pump can then be optimally positioned to locate the inlet in the ventricle and the outlet in the aorta.

Abstract: Intravascular blood pumps and methods of use. The blood pump include a pump portion that includes a collapsible blood conduit defining a blood flow lumen between an inflow and an outflow. The pump portion includes a distal collapsible impeller axially spaced from a proximal collapsible impeller, at least a portion of each of the distal and proximal collapsible impellers disposed between the inflow and the outflow.

Abstract: An intraocular lens is disclosed that includes an optic body with a projection extending radially outwards from a peripheral surface of the optic body. The projection comprises a haptic contact surface facing radially outward, wherein the entire haptic contact surface is a flat surface. A haptic having a free distal end and a proximal portion is secured to the projection along the haptic contact surface, wherein the projection and the proximal portion interface at a butt joint without the haptic extending into the projection and without the projection extending into the haptic. The haptic also includes a haptic fluid chamber.

Abstract: Catheter blood pump that include an expandable pump portion extending distally from an elongate shaft. The pump portions include an expandable impeller housing including an expandable blood conduit that defines a blood lumen between an inflow and an outflow. The pump portions include one or more expandable impellers disposed at least partially within the blood lumen.

Abstract: Catheter blood pumps that include collapsible blood conduits and one or more collapsible impellers. The catheter blood pumps include an outflow and an expandable flow diverter disposed in an outflow region. The expandable flow diverters can be completely proximal to a proximal end of the collapsible blood conduit.

Abstract: Methods and devices for supporting circulation. The methods may include positioning a blood pump in the arterial vasculature or the venous vasculature. The methods may include positioning a pump portion of the blood pump in a descending aorta, an inferior vena cava, a renal artery, and/or a renal vein. The methods include delivering a pump portion of a blood pump to a target location and rotating one or more impellers to move blood through the pump portion.

Abstract: An intravascular fluid movement device that includes an expandable member having a collapsed, delivery configuration and an expanded, deployed configuration, the expandable member having a proximal end and a distal end, a rotatable member disposed radially and axially within the expandable member, and a conduit coupled to the expandable member, the conduit at least partially defining a blood flow lumen between a distal end of the conduit and a proximal end of the conduit, the conduit disposed solely radially inside of the expandable member in a distal section of the expandable member.

Abstract: Accommodating intraocular lenses including an optic having an anterior element and a posterior element defining an optic fluid chamber, wherein the optic is aspheric across all powers throughout accommodation or disaccommodation. Intraocular lenses, optionally accommodating, where an optic portion is centered with a midline of a height of the peripheral portion, the height measured in the anterior to posterior direction.

Abstract: Devices for moving blood within a patient, and methods of doing so. The devices can include a pump portion that includes an impeller and a housing around the impeller, as well as a fluid lumen. The impeller can be activated to cause rotation of the impeller and thereby move fluid within the fluid lumen.

Abstract: Catheter blood pumps that include an expandable pump portion. The pump portions include an collapsible blood conduit that defines a blood lumen. The collapsible blood conduits include a collapsible scaffold adapted to provide radial support to the blood conduit. The pump portion also includes one or more impellers.

Abstract: Catheter blood pump that include an expandable pump portion extending distally from an elongate shaft. The pump portions include an expandable impeller housing including an expandable blood conduit that defines a blood lumen between an inflow and an outflow. The pump portions include one or more expandable impellers disposed at least partially within the blood lumen.

Abstract: Accommodating intraocular lenses including an optic having an anterior element and a posterior element defining an optic fluid chamber, wherein the optic is aspheric across all powers throughout accommodation or disaccommodation. Intraocular lenses, optionally accommodating, where an optic portion is centered with a midline of a height of the peripheral portion, the height measured in the anterior to posterior direction.

Abstract: Methods and devices for supporting circulation. The methods may include positioning a blood pump in the arterial vasculature or the venous vasculature. The methods may include positioning a pump portion of the blood pump in a descending aorta, an inferior vena cava, a renal artery, and/or a renal vein. The methods include delivering a pump portion of a blood pump to a target location and rotating one or more impellers to move blood through the pump portion.

Abstract: Devices for moving blood within a patient, and methods of doing so. The devices can include a pump portion that includes an impeller and a housing around the impeller, as well as a fluid lumen. The impeller can be activated to cause rotation of the impeller and thereby move fluid within the fluid lumen.

Abstract: Intravascular blood pumps systems and methods of use are provided. The blood pump system includes a catheter portion having a distal blood pump with a cantilevered collapsible impeller. The blood pump includes sections of increased stiffness and sections of increased flexibility. The blood pump is designed and configured to bend at a distal tip, a central section, and in a proximal catheter shaft, while maintaining stiffness in the inlet and outlet. Collectively the pump is designed and configured to maintain tip gap between the impeller and the blood conduit without requiring any structures in the blood conduit distal to the impeller assembly.

Abstract: Catheter blood pumps that include an expandable conduit coupled to at least one hub shaped to promote smooth blood flow. In some examples, the at least one hub includes a body with radially extending arms that are coupled to struts of the conduit. The hub may include channels having curved surfaces for promoting non-turbulent fluid flow around a distal opening and/or a proximal opening of the conduit. The arms may have ridge regions that extend axially along the body of the hub to define at least a portion of the channels.

Abstract: Devices for moving blood within a patient, and methods of doing so. The devices can include a pump portion that includes an impeller and a housing around the impeller, as well as a fluid lumen. The impeller can be activated to cause rotation of the impeller and thereby move fluid within the fluid lumen.

Abstract: Catheter blood pumps that include an expandable conduit coupled to at least one hub shaped to promote smooth blood flow. In some examples, the at least one hub includes non-metallic configuration and the struts comprise a metallic configuration (e.g., nitinol). The hub can include one or more layers, including a combination of Chronoflex and Pebax.