Abstract: Advertising is targeted to a specific user of a user console. A product data request is received from a user console and includes a user identifier, user data, and at least a first product identifier. A user account record associated with the user identifier is identified. The user account record includes a subscription service level identifier and a user account history. The user data are then associated with the user account record. A product catalog is searched for any product related entries associated with the request, and when any product related entries associated with the product data request are found, each such product related entry is provided to the user console.

Abstract: Improved devices and methods for performing electroporation-mediated delivery agents to cells is described. The method includes positioning a first electrode and a second electrode such that an electrical signal passed between the first electrode and the second electrode passes through the cell. The method also includes passing an electrical signal between the first electrode and the second electrode, the electrical signal having a frequency greater than about 10 kHz. In one embodiment of the method, the electrical signal has a bipolar waveform. In another embodiment of the method, the electrodes are positioned at a treatment site, e.g., a tumor, for in vivo delivery of an agent.

Abstract: Described are electroporation plates (2) that comprise a plurality of energizable electroporation wells (4) or chambers arrayed in a solid substrate, wherein at least two of the wells (4) in the plate (2) can be independently energized. Each well (4) contains at least two electroporation electrodes (12, 14) disposed therein, and serves as the vessel in which an individual electroporation reaction can be conducted. Also, described are electroporation systems that use electroporation plates (2) according to the invention, as well as methods of using such electroporation plates (2) and systems, for example, to optimize electroporation conditions.

Abstract: A method for delivery of an agent to a cell using electroporation is disclosed. The method includes positioning a first electrode and a second electrode such that an electrical signal passed between the first electrode and the second electrode passes through the cell. The method also includes passing an electrical signal between the first electrode and the second electrode, the electrical signal having a frequency greater than about 10 kHz. In one embodiment of the method, the electrical signal has a bipolar waveform. In another embodiment of the method, the electrodes are positioned at a treatment site, e.g., a tumor, for in vivo delivery of an agent.

Abstract: The invention generally relates to an appliance leveling system that includes a bolt having a threaded portion and a diameter, a nut, and a threaded aperture configured to engage the threaded portion of the bolt, and an appliance leg including a first bolt receiving aperture and a nut receiving structure. The diameter of the first bolt receiving aperture is greater than the bolt diameter to provide free axial movement of the bolt relative to the first bolt receiving aperture. The nut receiving structure is configured to receive and retain the nut so that rotation of the bolt relative to the nut adjusts a vertical height of the appliance.

Abstract: A flue connection system for an appliance provides a flue connection member. The flue connection member defines an aperture and includes an extending member. The flue connection member is configured to be coupled to a flue duct and an appliance, including a fireplace. An appliance connection member may also be provided for attachment to the appliance. The flue connection member and the appliance connection member are configured to be coupled to one another with the flue connection member positioned in contact with the appliance connection member.

Abstract: A method for delivery of an agent to a cell using electroporation is disclosed. The method includes positioning a first electrode and a second electrode such that an electrical signal passed between the first electrode and the second electrode passes through the cell. The method also includes passing an electrical signal between the first electrode and the second electrode, the electrical signal having a frequency greater than about 10 kHz. In one embodiment of the method, the electrical signal has a bipolar waveform. In another embodiment of the method, the electrodes are positioned at a treatment site, e.g., a tumor, for in vivo delivery of an agent.

Abstract: A method for delivery of an agent to a cell using electroporation is disclosed. The method includes positioning a first electrode and a second electrode such that an electrical signal passed between the first electrode and the second electrode passes through the cell. The method also includes passing an electrical signal between the first electrode and the second electrode, the electrical signal having a frequency greater than about 10 kHz. In one embodiment of the method, the electrical signal has a bipolar waveform. In another embodiment of the method, the electrodes are positioned at a treatment site, e.g., a tumor, for in vivo delivery of an agent.

Abstract: A fluid pressure regulator capable of adjustably setting a cut-off pressure between an upper and a lower limit having a two-piece valve body where the two pieces are threadably joined such that adjusting the distance between the two pieces (34, 54) of the valve body moves a piston (12) stem valve operating a high pressure port (40) towards or away from the high pressure port while not changing the distance between a spring (84) engaging the piston (12) and the piston head (14).

Abstract: A fluid pressure regulator capable of adjustably setting a cut-off pressure between an upper and a lower limit having a two-piece valve body where the two pieces are threadably joined such that adjusting the distance between the two pieces of the valve body moves a piston stem valve operating a high pressure port towards or away from the high pressure port while not changing the distance between the spring engaging the piston and the piston head.

Abstract: A fluid pressure regulator capable of adjustably setting a cut-off pressure between an upper and a lower limit having a two-piece valve body where the two pieces are threadably joined such that adjusting the distance between the two pieces of the valve body moves a piston stem valve operating a high pressure port towards or away from the high pressure port while not changing the distance between the spring engaging the piston and the piston head.