Abstract: This disclosure relates to new assay methods for analysis of circulating tumor cells (CTCs) in blood samples for detection, e.g., early detection, and/or monitoring of disease, e.g., cancer. The methods provide ultra-high sensitivity and specificity, and include the use of microfluidic isolation of CTCs and digital detection of RNA derived from the CTCs.

Abstract: A camera may capture reflected light from the surface of the wafer during a semiconductor process that adds or removes material from the wafer, such as an etch process. To accurately determine an endpoint for the process, a camera sampling rate and light source intensity may be optimized in the process recipe. Optimizing the light source intensity may include characterizing light intensities that will be reflected from the waiver using an image of the wafer. Pixel intensities may be used to adjust the light source intensity to compensate for more complex wafer patterns. Optimizing the camera sampling rates may include nondestructively rotating a view of the wafer and converting the sampled intensities to the frequency domain. The camera sampling rate may be increased or decreased to remove spatial noise from the image without oversampling unnecessarily. These optimized parameters may then generate a clean, repeatable trace for endpoint determination.

Abstract: A method can include generating equipment specifications for a facility project at a field site by simulating physical phenomena using one or more computational simulators; using the equipment specifications and a computational facility planner system, generating a work breakdown structure for the facility project, where the work breakdown structure represents activities to be performed to deliver a defined scope of the facility project within a defined time; rendering a graphical user interface to a display that includes graphical controls for dependencies of the activities and equipment characterized by the equipment specifications; responsive to input received via one or more of the graphical controls, automatically updating at least durations of the activities; and, based at least in part on the updating, generating an optimal scenario for the facility project.

Abstract: Optical lenses and associated luminaire are described herein. In one aspect, a lens comprises a light receiving side comprising grooves for receiving light emitting diodes, the grooves defined by a central refractive region and walls comprising total internal reflection faces; and a light extraction side opposite the light receiving side, the light extraction side comprising refractive extraction surfaces, total internal reflection extraction surfaces, or combinations thereof. In some embodiments, luminaire comprises an array of light emitting diodes; and the lens positioned over the array of light emitting diodes.

Abstract: A sanitary device has a programmable electronic control unit that acts on a metering and mixer valve unit. The electronic control unit has a program memory suitable for the retrievable storage of multiple different water dispensing programs and a central data processing unit that acts on at least one actuator that actuates the metering and mixer valve unit. A user interface has a display that has a central display region and a peripheral display region annularly surrounding the central display region, a rotatable setting ring around the display and at least three buttons around the setting ring. The buttons of the user interface comprise a program selection button, an output button and a temperature button. Actuating a button results in the present setting value of the button function in question being displayed in the central display region of the display.

Abstract: A sanitary room of a building has an access point for persons and a sanitary station, which has a sanitary apparatus having a metering and mixing valve unit, a lighting apparatus, and a sound apparatus. A programmable electronic controller influences the metering and mixing valve unit, the lighting apparatus, and the sound apparatus. The electronic controller has a memory for storing water discharge programs, a memory for storing lighting programs, a memory for storing sound programs, and a data-processing unit, which operates an actuator of the metering and mixing valve unit, an illuminant controller, and a sound generator. The sanitary station includes a device user interface associated with the sanitary apparatus which allows one of the water discharge programs to be selected and manually modified. Adjacent the access point, a room user interface is provided, which allows lighting programs and sound programs to be selected and manually modified.

Abstract: Disclosed are pharmaceutical compositions comprising the peptide of SEQ ID No. 1, or a pharmaceutically acceptable salt or counterion thereof, methods of preparing such pharmaceutical compositions, and methods of treating diabetes and diabetes-related disorders with such pharmaceutical compositions.

Abstract: Disclosed are pharmaceutical compositions comprising the peptide of SEQ ID No. 1, or a pharmaceutically acceptable salt or counterion thereof, methods of preparing such pharmaceutical compositions, and methods of treating diabetes and diabetes-related disorders with such pharmaceutical compositions.

Abstract: An apparatus, system, method, and program product are disclosed for balancing usage across a foldable display. A method includes tracking one or more characteristics of an active portion of a foldable display. The active portion of the foldable display includes a portion of the foldable display that is enabled when the display is folded. The method includes determining an inactive portion of the foldable display that is disabled while the active portion of the foldable display is enabled when the display is folded. The method includes activating the inactive portion of the foldable display based on the one or more characteristics of the active portion of the foldable display such that usage of the active and inactive portions of the foldable display is substantially uniform.

Abstract: Various embodiments provide a handheld computing device, such as a cellular phone, that includes a fingerprint sensor embedded in the device's display active area. The fingerprint sensor is composed of a series of PIN diodes that are configured to operate in a photo-receiving mode. In various embodiments, the PIN diodes are formed as active matrix organic light emitting diodes (AMOLEDs) at least partially within the gap between pixels in the display active area.

Abstract: An apparatus, system, method, and program product are disclosed for balancing usage across a foldable display. A method includes tracking one or more characteristics of an active portion of a foldable display. The active portion of the foldable display includes a portion of the foldable display that is enabled when the display is folded. The method includes determining an inactive portion of the foldable display that is disabled while the active portion of the foldable display is enabled when the display is folded. The method includes activating the inactive portion of the foldable display based on the one or more characteristics of the active portion of the foldable display such that usage of the active and inactive portions of the foldable display is substantially uniform.

Abstract: Various embodiments provide a computing device that includes a self-compensating system embedded in the device's display active area. The self-compensating system is composed of a series of PIN diode circuits that include PIN diodes that are formed as active matrix organic light emitting diodes (AMOLEDs) at least partially within the gap between pixels in the display active area.

Abstract: Various embodiments provide a handheld computing device, such as a cellular phone, that includes a fingerprint sensor embedded in the device's display active area. The fingerprint sensor is composed of a series of PIN diodes that are configured to operate in a photo-receiving mode. In various embodiments, the PIN diodes are formed as active matrix organic light emitting diodes (AMOLEDs) at least partially within the gap between pixels in the display active area.

Abstract: A mold assembly or system includes a moldbase that holds mold inserts and has embedded fluid lines to facilitate cooling during part formation. Mold inserts combine to form mold cavities that receive carbon fiber and resin components to form a carbon composite based part. A permanent release coating along a mold component surface that contacts the carbon fiber and resin components facilitates the release of the finished part from the mold component. Guide pins and guide pin receiving holes facilitate accurate alignment of mold components. Ejector pins within respective ejector pin shafts help eject a finished part from a respective mold component. An ejector pin shaft cover transfers force from an ejector pin to eject a finished part and also prevents substantial passage of resin into the ejector pin shaft. A fluid actuated ejection system provides fluid based mechanical forces to the ejector pins to facilitate finished part ejection.

Abstract: A smart card reader including a smart card reading assembly including a plurality of smart card chip communication contacts and a static electricity discharge element assembled with the smart card reading assembly, the static electricity discharge element including a plurality of static electricity discharge contacts contacting multiple diverse surfaces of a smart card for discharge of static electricity thereon.

Abstract: A mold assembly or system includes a moldbase that holds mold inserts and has embedded fluid lines to facilitate cooling during part formation. Mold inserts combine to form mold cavities that receive carbon fiber and resin components to form a carbon composite based part. A permanent release coating along a mold component surface that contacts the carbon fiber and resin components facilitates the release of the finished part from the mold component. Guide pins and guide pin receiving holes facilitate accurate alignment of mold components. Ejector pins within respective ejector pin shafts help eject a finished part from a respective mold component. An ejector pin shaft cover transfers force from an ejector pin to eject a finished part and also prevents substantial passage of resin into the ejector pin shaft. A fluid actuated ejection system provides fluid based mechanical forces to the ejector pins to facilitate finished part ejection.

Abstract: A mold assembly or system includes a moldbase that holds mold inserts and has embedded fluid lines to facilitate cooling during part formation. Mold inserts combine to form mold cavities that receive carbon fiber and resin components to form a carbon composite based part. A permanent release coating along a mold component surface that contacts the carbon fiber and resin components facilitates the release of the finished part from the mold component. Guide pins and guide pin receiving holes facilitate accurate alignment of mold components. Ejector pins within respective ejector pin shafts help eject a finished part from a respective mold component. An ejector pin shaft cover transfers force from an ejector pin to eject a finished part and also prevents substantial passage of resin into the ejector pin shaft. A fluid actuated ejection system provides fluid based mechanical forces to the ejector pins to facilitate finished part ejection.

Abstract: A smart card reader including a smart card reading assembly including a plurality of smart card chip communication contacts and a static electricity discharge element assembled with the smart card reading assembly, the static electricity discharge element including a plurality of static electricity discharge contacts contacting multiple diverse surfaces of a smart card for discharge of static electricity thereon.

Abstract: A device for containing sensitive data including a housing, an anti-tamper protected enclosure located within the housing and being adapted to contain the sensitive data, anti-tamper protection circuitry located within the anti-tamper protected enclosure and at least one ball grid array arranged within the housing and mounted on an outer surface of the anti-tamper protected enclosure and electrically coupled to the anti-tamper protection circuitry for protecting against unauthorized access to the interior of the anti-tamper protected enclosure.

Abstract: A device for containing sensitive data including a housing, an anti-tamper protected enclosure located within the housing and being adapted to contain the sensitive data, anti-tamper protection circuitry located within the anti-tamper protected enclosure and at least one ball grid array arranged within the housing and mounted on an outer surface of the anti-tamper protected enclosure and electrically coupled to the anti-tamper protection circuitry for protecting against unauthorized access to the interior of the anti-tamper protected enclosure.