Abstract: Compositions, systems, and methods are disclosed for preparing and utilizing arrays, such as single-analyte arrays containing a plurality of fiducial elements with random spatial distributions. Arrays may be prepared with pluralities of fiducial elements comprising optically active or passive moieties. Arrays containing random spatial distributions of fiducial elements may be utilized for various array-based processes that require spatial information.

Abstract: A microfluidic mixer, formed by two parts, a first part being a substrate having formations defining fluid channels on an outer surface that is directed towards a second part, which is a flexible layer. The flexile layer has formations defining a fluid channel which, when the flexible layer is positioned over the substrate so as to cover the fluid channels of the substrate provides a fluid communication path. A section of said communication path comprises at least first and second fluid channels for providing first and second fluids. The first and second fluid channels merge before an inlet of a mixing chamber. The mixing chamber comprises perturbation formations. An outlet of the mixing chamber is connected to an outlet fluid channel. The flexible layer comprises points for compression at the inlet and outlet of the mixing chamber for closing the merged fluid channel. The perturbation formations of the mixing chamber are vertically arranged vertically with respect to an inner surface.

Abstract: A microfluidic flow controller comprising a substrate having formations defining two or more fluid channels having channel fluid ports which are open at an outer surface of the substrate; and a flexible layer having formations defining a fluid channel which, when the flexible layer is positioned over the substrate so as to cover at least the channel fluid ports, provides a fluid communication path between the channel fluid ports but which, when a force is applied to press the flexible layer towards the substrate, deforms so as to inhibit fluid communication between the channel fluid ports.

Abstract: Aspects of the present disclosure include methods and systems for determining drop delay of a flow stream in a flow cytometer. Methods according to certain embodiments include obtaining a first frequency (f1) of drop perturbation of a flow stream subjected to an oscillating vibration, capturing one or more images of the flow stream in a detection field, obtaining a second frequency (f2) of drop perturbation of the flow stream based on one or more of the captured images and determining the drop delay of the flow stream based on the first frequency and the second frequency. Systems for practicing the subject methods having an imaging sensor for capturing one or more images of the flow stream and a processor configured to calculate drop delay using one or more of the captured images are also provided. Non-transitory computer readable storage mediums are also described.

Abstract: Aspects of the present disclosure include methods and systems for determining drop delay of a flow stream in a flow cytometer. Methods according to certain embodiments include obtaining a first frequency (f1) of drop perturbation of a flow stream subjected to an oscillating vibration, capturing one or more images of the flow stream in a detection field, obtaining a second frequency (f2) of drop perturbation of the flow stream based on one or more of the captured images and determining the drop delay of the flow stream based on the first frequency and the second frequency. Systems for practicing the subject methods having an imaging sensor for capturing one or more images of the flow stream and a processor configured to calculate drop delay using one or more of the captured images are also provided. Non-transitory computer readable storage mediums are also described.

Abstract: A microfluidic flow controller comprising a substrate having formations defining two or more fluid channels having channel fluid ports which are open at an outer surface of the substrate; and a flexible layer having formations defining a fluid channel which, when the flexible layer is positioned over the substrate so as to cover at least the channel fluid ports, provides a fluid communication path between the channel fluid ports but which, when a force is applied to press the flexible layer towards the substrate, deforms so as to inhibit fluid communication between the channel fluid ports.

Abstract: This invention relates to an overfill prevention system for preventing the overfilling of tanks when filling up large tanks from a fuel distribution truck. The system operates by monitoring and automatically controlling the filling process by use of a power take off switch assembly that is connected electronically to a secondary overfill prevention system that is also connected to a signal probe located in the tank that is being filled. In operation, once fuel contacts the signal probe, a communicator signal is sent from the signal probe to a secondary overfill prevention system, which interrupts a looping electrical current through a fuel shut off sensor assembly to a power take off switch assembly along a connecting cable.

Abstract: This invention relates to an overfill prevention system for preventing the overfilling of tanks when filling up large tanks from a fuel distribution truck. The system operates by monitoring and automatically controlling the filling process by use of a power take off switch assembly that is connected electronically to a secondary overfill prevention system that is also connected to a signal probe located in the tank that is being filled. In operation, once fuel contacts the signal probe, a communicator signal is sent from the signal probe to a secondary overfill prevention system, which interrupts a looping electrical current through a fuel shut off sensor assembly to a power take off switch assembly along a connecting cable.

Abstract: A novel process for the preparation of hydantoin sulfonyl chlorides of general formula (I) wherein R and n are as specified in the description, and certain novel intermediates thereto, are disclosed.

Abstract: A novel process for the preparation of hydantoin sulfonyl chlorides of general formula (I) wherein R and n are as specified in the description, and certain novel intermediates thereto, are disclosed.

Abstract: The invention relates to a blow-out system for a plug-in component, for example an automatic cutout or a circuit breaker, and has a component housing (10, 20), at least one contact stud (40) arranged on a housing back, as well as at least one latching element (30), arranged on the housing back, for securing the component housing in the installed position. A bundle of laminations provided in the component for extinguishing an electric arc forming in the component has a blow-out channel (50), which is formed adjoining the bundle of laminations and leads to the outside of the housing, the blow-out channel (50) being partially limited by the latching element (30) on the housing outside.