Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.

Abstract: Systems disclosed herein are directed to a display stand unit for a retail environment. The display stand unit includes a base having an interior and a display stand. The display stand includes a stem that connects to and extends upwardly from the base and a receiving surface that is suspended above and spaced away from the base by the stem. The receiving surface is configured to releasably hold an electronic device above and spaced away from the base. The display stand unit further includes a security cable that extends out from the base. The security cable is configured to attach to the electronic device to movably secure the electronic device to the base. The display stand unit further includes a retractor disposed within the interior of the base and connected to the security cable. The retractor automatically retracts the security cable.

Abstract: An exemplary system according to the present disclosure comprises a computing device that in operation, causes the system to receive financial product or financial portfolio data, map the financial product to a risk factor, execute a risk factor simulation process involving the risk factor, generate product profit and loss values for the financial product or portfolio profit and loss values for the financial portfolio based on the risk factor simulation process, and determine an initial margin for the financial product. The risk factor simulation process can be a filtered historical simulation process.

Abstract: An exemplary system according to the present disclosure comprises a computing device that in operation, causes the system to receive financial product or financial portfolio data, map the financial product to a risk factor, execute a risk factor simulation process involving the risk factor, generate product profit and loss values for the financial product or portfolio profit and loss values for the financial portfolio based on the risk factor simulation process, and determine an initial margin for the financial product. The risk factor simulation process can be a filtered historical simulation process.

Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.

Abstract: An exemplary system according to the present disclosure comprises a computing device that in operation, causes the system to receive financial product or financial portfolio data, map the financial product to a risk factor, execute a risk factor simulation process involving the risk factor, generate product profit and loss values for the financial product or portfolio profit and loss values for the financial portfolio based on the risk factor simulation process, and determine an initial margin for the financial product. The risk factor simulation process can be a filtered historical simulation process.

Abstract: Disclosed herein are pyrazole pyrimidine compounds that modulate and/or inhibit hematopoietic progenitor kinase 1, as well as methods of making such compounds and therapeutic methods of using same.

Abstract: Methods, systems, and devices for wireless communications are described. A user equipment (UE) may determine that a cell is associated with a deployment mode based on a condition being satisfied, where the deployment mode may be associated with serving one or more UEs travelling at high speeds. The UE may select from one of a frequency-based initial cell selection or a cell-based initial cell selection and may measure one or more frequencies of one or more cells including the cell to obtain a set of measured parameters, each cell corresponding to a respective deployment mode and a respective measured parameter. The UE may select a candidate cell from the one or more cells based on the respective measured parameters of each cell and the respective deployment modes of each cell and may establish a connection with the candidate cell based on the selecting.

Abstract: A semiconductor structure including a double patterned structure and a method for forming the semiconductor structure are provided. A negative photoresist layer is formed on a positive photoresist layer, which is formed over a substrate. An exposure process is performed to form a first exposure region in the positive photoresist layer and to form a second exposure region in the negative photoresist layer in response to a first and a second intensity thresholds of the exposure energy. A negative-tone development process is performed to remove portions of the negative photoresist layer to form first opening(s). The positive photoresist layer is then etched along the first opening(s) to form second opening(s) therein. A positive-tone development process is performed to remove the first exposure region therefrom to form a double patterned positive photoresist layer.

Abstract: A semiconductor structure including a double patterned structure and a method for forming the semiconductor structure are provided. A positive photoresist layer is formed on a negative photoresist layer, which is formed over a substrate. An exposure process is performed to form a first exposure region in the positive photoresist layer and to form a second exposure region in the negative photoresist layer in response to a first and a second intensity thresholds of the exposure energy. A positive-tone development process is performed to remove the first exposure region from the positive photoresist layer to form first opening(s). The second exposure region in the negative photoresist layer is then etched along the first opening(s) to form second opening(s) therein. A negative-tone development process is performed to remove portions of the negative photoresist layer outside of remaining second exposure region to form a double patterned negative photoresist layer.

Abstract: Various embodiments provide a semiconductor structure and fabrication method. An exemplary semiconductor structure can include a semiconductor substrate having an isolation trench formed in the semiconductor substrate. A first barrier layer can be disposed on a bottom surface and a sidewall of the isolation trench. A light absorption layer can be disposed at least on a surface portion of the first barrier layer over the bottom surface of the isolation trench. A second barrier layer can fill the isolation trench to form an isolation structure in the semiconductor substrate. The isolation structure can have a top surface flushed with or over a top surface of the semiconductor substrate.

Abstract: A semiconductor structure including a double patterned structure and a method for forming the semiconductor structure are provided. A negative photoresist layer is formed on a positive photoresist layer, which is formed over a substrate. An exposure process is performed to form a first exposure region in the positive photoresist layer and to form a second exposure region in the negative photoresist layer in response to a first and a second intensity thresholds of the exposure energy. A negative-tone development process is performed to remove portions of the negative photoresist layer to form first opening(s). The positive photoresist layer is then etched along the first opening(s) to form second opening(s) therein. A positive-tone development process is performed to remove the first exposure region therefrom to form a double patterned positive photoresist layer.

Abstract: Digital image capture and processing engine of modular design and employing an optical waveguide structure for collecting and guiding LED-based illumination during object illumination and imaging operations. The digital image capture and processing engine also includes apparatus for automatically controlling the duration of illumination produced from LED illumination arrays during object illumination and imaging operations. Such automatic illumination control involves measuring the amount of illumination to which the object be imaged has been exposed, and controlling the duration of illumination produced from the LED illumination arrays based on such measurements during each object illumination and imaging operation. By virtue of the present invention, the digital image capture and processing engine ensures the reliable formation and detection of high quality images in diverse application environments in the digital image capture and processing engine can be used.

Abstract: A digital image capture and processing system having a housing with a light transmission window, and an illumination subsystem including an illumination board disposed adjacent the light transmission window, configured substantially within a plane, and having a central aperture mounted adjacent the imaging window. The illumination board supports an array of illumination sources mounted around at least portion of the central aperture, for producing and a field of illumination within the FOV of its image formation and detection subsystem during object illumination and imaging operations. A FOV folding mirror is mounted within the housing and beneath the illumination board, and folds the path of the FOV beneath the light transmission aperture and directs and projects the FOV out through the central aperture. Also, an automatic illumination control subsystem is provided for controlling the array of illumination sources during object illumination and imaging operations.

Abstract: An automatic digital video-imaging based code symbol reading system for use in point of sale (POS) environments, employing automatic object motion detection and illumination control, and digital video-imaging based code symbol reading techniques, which ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments, while providing the versatility required to accommodate the different ways in which operators present objects for code symbol reading at POS environments.

Abstract: An automatic digital video imaging based code symbol reading system for use in point of sale (POS) environments, employing automatic object motion detection and illumination control, and digital video imaging based code symbol reading techniques, which ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments, while providing the versatility required to accommodate the different ways in which operators present objects for code symbol reading at POS environments.

Abstract: An automatic automatically-triggered digital video imaging based code symbol reading system for use in point of sale (POS) environments, employing an adaptive control process involving the real-time analysis of the exposure quality of captured frames of digital image data and the real-time reconfiguration of system control parameters (SCPs) based on the results of such exposure quality analysis. By virtue of the present invention, the system enables the reliable reading of code symbols graphically represented in digital images, under demanding point-of-sale lighting conditions and other challenging environments.

Abstract: An automatic code symbol reading system for use in point of sale (POS) environments, employing automatic object motion detection and illumination control, and digital video image capturing and processing techniques, which ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments, while providing versatility required to accommodate the different ways in which human operators present objects for code symbol reading at POS environments.

Abstract: An automatic digital-imaging based code symbol reading system supporting a presentation mode of system operation, automatic object direction detection and illumination control, and video image capture and processing techniques. By virtue of the present invention, the automatic digital-imaging based code symbol reading system ensures the reliable reading of code symbols graphically represented in digital images, in high-throughput point-of-sale and other environments.

Abstract: A digital image capture and processing system employing automated real-time analysis of digital image exposure quality to automatically reconfigure system control parameters, and dynamically control illumination and imaging operations within the digital image capture and processing system.