Abstract: This disclosure details integrated thermal management systems for thermally managing electrified vehicle components. Exemplary integrated thermal management systems may include a thermal module assembly that may be integrated into a front end structure of a flexible modular platform of the electrified vehicle. The integrated thermal management systems may be controlled in a plurality of distinct thermal control modes for thermal managing various subcomponents and for addressing various vehicle auxiliary loads (e.g., passenger cabin heating loads, passenger cabin cooling loads, etc.).

Abstract: A fabrication method of a hexagonal boron nitride (h-BN)-based thermally-conductive composite film includes the following steps: S1. attaching an adhesive layer to an h-BN film carried on a carrier film, and separating the h-BN film from the carrier film to obtain a film in which an adhesive layer side is defined as a side A and an h-BN film side is defined as a side B; S2. attaching an adhesive layer to the side B of the film obtained in S1; S3. pasting a high-power graphite film to the side B of a film obtained in S2; S4. attaching an adhesive layer to the side B of a film obtained in S3; and S5. shaping a film obtained in S4 according to a required size. The present fabrication method is conducive to improving the production efficiency or yield rate of a thermally-conductive film product and the product quality.

Abstract: A fabrication method of a hexagonal boron nitride (h-BN)-based thermally-conductive composite film includes the following steps: S1. attaching an adhesive layer to an h-BN film carried on a carrier film, and separating the h-BN film from the carrier film to obtain a film in which an adhesive layer side is defined as a side A and an h-BN film side is defined as a side B; S2. attaching an adhesive layer to the side B of the film obtained in S1; S3. pasting a high-power graphite film to the side B of a film obtained in S2; S4. attaching an adhesive layer to the side B of a film obtained in S3; and S5. shaping a film obtained in S4 according to a required size. The present fabrication method is conducive to improving the production efficiency or yield rate of a thermally-conductive film product and the product quality.

Abstract: A single-cavity multi-runner applied to oriented arrangement extrusion molding equipment of graphene fibers includes a first extrusion cavity, the first extrusion cavity includes a first inlet and a first outlet arranged opposite to each other; a first molding cavity, the first molding cavity is arranged in an inclined manner, a second inlet is arranged at the high position end, a second outlet is arranged at the low position end of the first molding cavity, and the second inlet is connected to the first outlet; flow channels, the flow channels are formed by dividing the first molding cavity using baffle plates arranged horizontally and along the flowing direction of a heat-conducting mixture; a second molding cavity, the second molding cavity includes a third inlet and a third outlet arranged opposite to each other, the third inlet is connected to the outflow end of the flow channels.

Abstract: A single-cavity multi-runner applied to oriented arrangement extrusion molding equipment of graphene fibers includes a first extrusion cavity, the first extrusion cavity includes a first inlet and a first outlet arranged opposite to each other; a first molding cavity, the first molding cavity is arranged in an inclined manner, a second inlet is arranged at the high position end, a second outlet is arranged at the low position end of the first molding cavity, and the second inlet is connected to the first outlet; flow channels, the flow channels are formed by dividing the first molding cavity using baffle plates arranged horizontally and along the flowing direction of a heat-conducting mixture; a second molding cavity, the second molding cavity includes a third inlet and a third outlet arranged opposite to each other, the third inlet is connected to the outflow end of the flow channels.

Abstract: A device for preparing a thermally conductive sheet with graphene fibers in an oriented arrangement includes a first mold and a second mold. The first mold is configured to press a first cuboid block, and the second mold is configured to repeatedly press the first cuboid block. The first mold is provided with a first mold groove. A first mold cover covers an opening end of the first mold groove, and the first mold cover and the first mold are configured to press the first cuboid block. A second mold groove is arranged on one side of the second mold, and a second mold cover is arranged at an opening end of the second mold groove. A movable thickness limiting block is arranged at a side of the second mold cover adjacent to the second mold groove, and is configured to be clamped in the second mold groove.

Abstract: Provided herein are magnetic resonance imaging (MRI) compatible, convection-enhanced delivery (CED) cranial implant devices and related methods for performing a wide array of therapeutic and/or monitoring applications. In one aspect, the cranial implant device includes a cranial implant housing configured for intercranial implantation in a cranial opening of a subject. The cranial implant housing comprises a substantially anatomically-compatible shape, at least first and second surfaces, and at least one fluidic circuit comprising at least one cavity and at least one port that fluidly communicates with the cavity through at least the second surface, in which the cavity comprises, or is capable of comprising, at least one fluidic therapeutic agent.

Abstract: A device for preparing a thermally conductive sheet with graphene fibers in an oriented arrangement includes a first mold and a second mold. The first mold is configured to press a first cuboid block, and the second mold is configured to repeatedly press the first cuboid block. The first mold is provided with a first mold groove. A first mold cover covers an opening end of the first mold groove, and the first mold cover and the first mold are configured to press the first cuboid block. A second mold groove is arranged on one side of the second mold, and a second mold cover is arranged at an opening end of the second mold groove. A movable thickness limiting block is arranged at a side of the second mold cover adjacent to the second mold groove, and is configured to be clamped in the second mold groove.

Abstract: Methods, systems, and techniques for determining whether an event has occurred from dynamic strain measurements involve determining, using a processor, at least one event parameter from a signal representing the dynamic strain measurements, and then having the processor use the at least one event parameter to determine whether the event has occurred. The at least one event parameter is any one or more of a measure of magnitude of the signal, frequency centroid of the signal, filtered baseline of the signal, harmonic power of the signal, and time-integrated spectrum flux of the signal.

Abstract: The present invention comprises methods and formulations to increase drug payload, especially in regard to a receptacle-based, inhalation dosed, dry powder therapeutic, wherein the methods and formulations are characterized by a high product density, as well as a high TLD per receptacle, while maintaining highly efficient aerosol performance from the device. Embodiments of the present invention comprise a spray-dried pharmaceutical powder comprising particles deliverable from a dry powder inhaler, the composition comprising active agent, and a shell-forming excipient, wherein the powder is characterized by a product density greater than 50 mg/ml.

Abstract: The invention provides molecules, e.g., antibodies or antibody fragments, that specifically bind thymic stromal lymphopoietin (TSLP), compositions comprising these molecules, and methods of using and producing these molecules.

Abstract: Embodiments of the invention relate to particulate agents and compositions comprising particulate agents for inhalation, and methods for preparing such particulate agents and compositions for inhalation, as well as therapeutic methods. Embodiments of the method comprise preparing an emulsion by combining an oil phase dispersion of hydrophobic seed particles and an aqueous dispersion comprising an emulsifier and an emulsion stabilizer and preparing a feedstock comprising encapsulated particles by homogenizing the emulsion, and forming a plurality of coated particles by spray drying the feedstock, wherein resulting particles comprises a porous shell disposed on or over a core and the core comprises at least one hydrophobic seed particle.

Abstract: The invention provides molecules, e.g., antibodies or antibody fragments, that specifically bind thymic stromal lymphopoietin (TSLP), compositions comprising these molecules, and methods of using and producing these molecules.

Abstract: Embodiments of the invention relate to a process for enhancing the bioavailability of poorly soluble active ingredients, and to formulations of powders made by such process. Embodiments of the invention comprise a spinodal decomposition method by which low, sparingly or poorly-soluble materials are converted to amorphous materials with, improved or enhanced solubility suitable for therapeutic use. The powder formulations are useful for the treatment of diseases and conditions, especially respiratory diseases and conditions.

Abstract: Methods, systems, and techniques for determining whether an event has occurred from dynamic strain measurements involve determining, using a processor, at least one event parameter from a signal representing the dynamic strain measurements, and then having the processor use the at least one event parameter to determine whether the event has occurred. The at least one event parameter is any one or more of a measure of magnitude of the signal, frequency centroid of the signal, filtered baseline of the signal, harmonic power of the signal, and time-integrated spectrum flux of the signal.

Abstract: The present invention is a heat extraction, waterproof, and daylighting roof device, which includes a water leakage top assembled above a roof. The water leakage top has a first air vent and a left end edge. A left extension water leakage top, a right extension water leakage top, an expel air vent, and a guide plate are mounted above the first air vent, and water leakage holes are provided between the left extension water leakage top and the water leakage top. The guide plate is positioned below the expel air vent; the guide plate is provided with an upward facing right crooked plate and an upward facing left crooked plate on two sides thereof. The left crooked plate is provided with a plurality of overflow holes, during heavy rain, the guide plate provides a function similar to an overflow container that prevents spilling over to the first air vent.

Abstract: Methods, systems, and techniques for determining whether an event has occurred from dynamic strain measurements involve determining, using a processor, at least one event parameter from a signal representing the dynamic strain measurements, and then having the processor use the at least one event parameter to determine whether the event has occurred. The at least one event parameter is any one or more of a measure of magnitude of the signal, frequency centroid of the signal, filtered baseline of the signal, harmonic power of the signal, and time-integrated spectrum flux of the signal.

Abstract: A battery pack is provided for a mobile communication device, comprising a casing defining a cavity that conforms, at least partially, to the outer shape of the mobile communication device and one or more rechargeable power cells housed within the thickness of the casing. An internal interface engages a corresponding interface on the mobile communication device to provide power from the one or more rechargeable cells to the mobile communication device. An external interface is electrically coupled to the internal interface in order to transmit signals from the mobile communication device to an external device and may further serve to recharge the one or more rechargeable power cells. The battery pack may also serve as an extendible platform by providing additional integrated communication interfaces and/or processors that can be utilized by the mobile communication device to extend its communication and/or processing capabilities.

Abstract: A battery pack is provided for a mobile communication device, comprising a casing defining a cavity that conforms, at least partially, to the outer shape of the mobile communication device and one or more rechargeable power cells housed within the thickness of the casing. An internal interface engages a corresponding interface on the mobile communication device to provide power from the one or more rechargeable cells to the mobile communication device. An external interface is electrically coupled to the internal interface in order to transmit signals from the mobile communication device to an external device and may further serve to recharge the one or more rechargeable power cells. The battery pack may also serve as an extendible platform by providing additional integrated communication interfaces and/or processors that can be utilized by the mobile communication device to extend its communication and/or processing capabilities.