Abstract: The present invention provides compounds of Formula (I): wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subject (e.g., a human).

Abstract: The present invention provides compounds of Formula (I): wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subject (e.g., a human).

Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (Formula One).

Abstract: A method for manufacturing an insulation member for a vacuum insulated structure includes the steps of forming a bag that has an opening using a single layer porous fabric, filling the bag with insulation materials via the opening, sealing the opening of the bag, and vibrating the bag to evenly distribute, de-aerate, and densify the insulation material to form a pillow. The method further includes the steps of compressing the pillow within a mold to define a compressed insulation member, and evacuating the compressed insulation member within an insulated structure to define a vacuum insulated structure.

Abstract: Continued and precise operation of an agricultural implement exists even where a subsystem, such as a GPS receiver, wireless communicator, a sensor, or the like, fails, falters, or is otherwise unusable. Data is continually tracked to the extent possible during failure or faltering and is temporarily stored. The temporary data is later stitched or otherwise harmonized with historical data once the failing system is repaired or otherwise once again available. During failure or faltering, views, and even mapped views, of historical and real-time data are displayed. Predicted or anticipated data can be included within these views or can even be used when stitching.

Abstract: Continued and precise operation of an agricultural implement exists even where a subsystem, such as a GPS receiver, wireless communicator, a sensor, or the like, fails, falters, or is otherwise unusable. Data is continually tracked to the extent possible during failure or faltering and is temporarily stored. The temporary data is later stitched or otherwise harmonized with historical data once the failing system is repaired or otherwise once again available. During failure or faltering, views, and even mapped views, of historical and real-time data are displayed. Predicted or anticipated data can be included within these views or can even be used when stitching.

Abstract: Systems and methods for fail-safe corrective actions based on vision information for autonomous driving. An example method is implemented by a processor system included in a vehicle, with the method comprising obtaining images from image sensors positioned about the vehicle. Visibility information is determined for at least a portion of the images. Adjustment of operation of an autonomous vehicle is caused based on the visibility information.

Abstract: A method for orthodontic treatment includes providing a first set of aligners to a user. The first set of aligners includes a first aligner, a second aligner, and a third aligner configured to move a tooth of a user. The first aligner, the second aligner, and the third aligner are created using a single physical dental model and are substantially the same shape. The first aligner has a first thickness, the second aligner has a second thickness, and the third aligner has a third thickness. The first thickness is different than the second thickness and the third thickness, and the second thickness is at least substantially equivalent to the third thickness.

Abstract: A snow plow blade attachment with is fixable to a lower edge of a snow plow blade to better prevent damage to a road or driveway during, in particular those formed by gravel, plowing. The detachable snow plow blade attachment comprises a tubular member having two posts which are designed to fit through holes in the base plate of the snow plow blade, and are detachably fixed thereto.

Abstract: Continued and precise operation of an agricultural implement exists even where a subsystem, such as a GPS receiver, wireless communicator, a sensor, or the like, fails, falters, or is otherwise unusable. Data is continually tracked to the extent possible during failure or faltering and is temporarily stored. The temporary data is later stitched or otherwise harmonized with historical data once the failing system is repaired or otherwise once again available. During failure or faltering, views, and even mapped views, of historical and real-time data are displayed. Predicted or anticipated data can be included within these views or can even be used when stitching.

Abstract: A method for analyzing a dental impression including receiving, by a dental impression review computer system, an image of a first dental impression administered by a user of the user's teeth, analyzing, by the dental impression review computer system, the image of the first dental impression, and providing, by the dental impression review computer system, feedback to the user based on the analysis.

Abstract: A magnetic module in a circuit interrupting system is configured to generate a blow-on force that pushes a moving contact toward a stationary contact. The magnetic module includes: a coil conductor having an opening through which a moving stem of the moving contact may move, wherein the coil conductor is electrically connected to the moving stem and a first auxiliary conductor, wherein the coil conductor is configured to allow current to flow from the moving stem to the first auxiliary conductor; a plunger attached to an end of the moving stem; and a first magnetic core shaped to fit around a first section of the coil conductor, wherein the first magnetic core is configured, when current flows through the coil conductor to the first auxiliary conductor, to become magnetized, attract the plunger toward the magnetic core, and cause the moving stem of the moving contact to move toward the stationary contact.

Abstract: A method for orthodontic treatment includes providing an aligner configured to move a tooth of a user and providing a movement stimulus associated with the aligner where the movement stimulus is configured to move the tooth of the user substantially the same amount when the aligner is worn by the user less than twenty-two hours a day according to a treatment plan specifying a total number of treatment days than the aligner alone would be able to move the tooth when worn for at least twenty-two hours a day for the total number of treatment days.

Abstract: A method for orthodontic treatment includes providing a first set of aligners to a user. The first set of aligners includes a first aligner, a second aligner, and a third aligner configured to move a tooth of a user. The first aligner, the second aligner, and the third aligner are created using a single physical dental model and are substantially the same shape. The first aligner has a first thickness, the second aligner has a second thickness, and the third aligner has a third thickness. The first thickness is different than the second thickness and the third thickness, and the second thickness is at least substantially equivalent to the third thickness.

Abstract: A magnetic module in a circuit interrupting system is configured to generate a blow-on force that pushes a moving contact toward a stationary contact. The magnetic module includes: a coil conductor having an opening through which a moving stem of the moving contact may move, wherein the coil conductor is electrically connected to the moving stem and a first auxiliary conductor, wherein the coil conductor is configured to allow current to flow from the moving stem to the first auxiliary conductor; a plunger attached to an end of the moving stem; and a first magnetic core shaped to fit around a first section of the coil conductor, wherein the first magnetic core is configured, when current flows through the coil conductor to the first auxiliary conductor, to become magnetized, attract the plunger toward the magnetic core, and cause the moving stem of the moving contact to move toward the stationary contact.

Abstract: A method and apparatus for field testing an NOx-sensor in a diesel engine exhaust system are disclosed. The apparatus is connectable to a truck having a lean burn diesel type engine, via an on-board diagnostic connector. A test cycle is performed on a running engine in at least two different states of operation, while NOx related values issued by the at least one NOx-sensor are measured over a predefined period of time. One state of operation is obtained by simultaneously opening the exhaust gas recirculation valve and controlling the back pressure valve for increasing backpressure. A dedicated algorithm is used to compare the measured values to a predefined model, and to provide a numerical summary and statistical evaluation of the sensor functioning.

Abstract: A system for graphically building a virtual network of computer components, the system including: a processor device for receiving an input library of components to form a network, and for devising communication pathways among the components; a display for displaying a proposed interconnection of components; and a memory device for storing component characteristics, wherein the processor device will produce a visual display of the proposed network based on the components selected for inclusion in the network.

Abstract: A method and apparatus for field testing and diagnosing at least one NOx-sensor in a diesel engine exhaust system are disclosed. The field testing apparatus is connectable to a truck having a lean burn diesel type engine, via an on-board diagnostic connector. The field testing apparatus is arranged to initiate a test cycle, and to diagnose at least one NOx-sensor in an exhaust system of the truck. The test cycle is performed on a running engine as a test sequence in a stationary truck, in at least two different states of operation, while NOx related values issued by the at least one NOx-sensor are measured over a predefined period of time. At least one state of operation is obtained by simultaneously opening the exhaust gas recirculation valve and controlling the back pressure valve for increasing backpressure. A dedicated algorithm is used to compare the measured values to a predefined model, and to provide a numerical summary and statistical evaluation of the sensor functioning.

Abstract: A swimming search and retrieval game is provided. The game includes the use of a faux environment in a body of water. The faux environment is configured to mimic a real life environment, such as a log, stump, coral, or ice environment. Items, such as replica animals associated with the real environment, are placed at and around the faux environment. Participants take turns retrieving the items from the faux environment based upon the type of play, such as most retrievals within an allotted time. The game difficulty can be increased by adding propellants for the environments and/or items to move the items during the retrieval.