Abstract: There is described a compound for use in the treatment of a mitochondrial DNA disorder, wherein the compound is a glycolysis inhibitor, an inhibitor of glutamine consumption or is L-asparaginase or pegaspargase. The glycolysis inhibitor may be a glucose analogue such as 2-deoxy-D-glucose (2DG) or 5-thioglucose (5TG). Also described is a method of treating a mitochondrial DNA disorder comprising administering a therapeutically effective amount of the compound above to a patient suffering from a mitochondrial DNA disorder. In addition, there is described a method of reducing the mtDNA heteroplasmy in the cells of a patient comprising administering a therapeutically effective amount of the compound above to the patient.

Abstract: A wildlife detection system includes a tracking device, a receiver, and a wildlife deterrent system. The tracking device may be mounted to a wildlife. The receiver is configured to track movement of the tracking device relative to an object of danger to the wildlife. The wildlife deterrent system is configured to reduce risk of danger to the wildlife in response to movement of the wildlife within a predetermined distance from the object of danger as tracked by the receiver.

Abstract: A wildlife detection system includes a tracking device, a receiver, and a wildlife deterrent system. The tracking device may be mounted to a wildlife. The receiver is configured to track movement of the tracking device relative to an object of danger to the wildlife. The wildlife deterrent system is configured to reduce risk of danger to the wildlife in response to movement of the wildlife within a predetermined distance from the object of danger as tracked by the receiver.