Patents by Inventor Daniel J. Brackett

Daniel J. Brackett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MICRORNA EXPRESSION PROFILE ASSOCIATED WITH PANCREATIC CANCER
    Publication number: 20180105865
    Abstract: Methods are provided for diagnosing whether a subject has, or is at risk of developing pancreatic cancer. The methods include measuring the level of at least one miR gene product in a biological sample derived from the subject's pancreas. An alteration in the level of the miR gene product in the biological sample as compared to the level of a corresponding miR gene product in a control sample, is indicative of the subject either having, or being at risk for developing, pancreatic cancer.
    Type: Application
    Filed: September 5, 2017
    Publication date: April 19, 2018
    Inventors: Thomas D. SCHMITTGEN, Daniel J. BRACKETT
  • MicroRNA Expression Profile Associated With Pancreatic Cancer
    Publication number: 20140357702
    Abstract: Methods are provided for diagnosing whether a subject has, or is at risk of developing, pancreatic cancer. The methods include measuring the level of at least one miR gene product in a biological sample derived from the subject's pancreas. An alteration in the level of the miR gene product in the biological sample as compared to the level of a corresponding miR gene product in a control sample, is indicative of the subject either having, or being at risk for developing, pancreatic cancer.
    Type: Application
    Filed: April 3, 2014
    Publication date: December 4, 2014
    Applicants: Board of Regents of the University of Oklahoma, Ohio State Innovation Foundation
    Inventors: Thomas D. Schmittgen, Daniel J. Brackett
  • Identification of biomarkers in biological samples and methods of using same
    Patent number: 8710429
    Abstract: The present invention is directed to methods of identifying biomarkers in liquid biological samples obtained from cancer patients or patients exhibiting a disease state. Such methods may include the use of electrospray ionization-time of flight mass spectrometry (ESI-TOF MS).
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: April 29, 2014
    Assignee: The Board of Regents of the University of OK
    Inventors: Jay S. Hanas, James R. Hocker, Daniel J. Brackett, Russell G. Postier, Marvin D. Peyton, John Y. Cheung
  • MICRORNA EXPRESSION PROFILE ASSOCIATED WITH PANCREATIC CANCER
    Publication number: 20110171646
    Abstract: Methods are provided for diagnosing whether a subject has, or is at risk of developing, pancreatic cancer. The methods include measuring the level of at least one miR gene product in a biological sample derived from the subject's pancreas.
    Type: Application
    Filed: December 7, 2010
    Publication date: July 14, 2011
    Applicants: The Ohio State University Research Foundation, Board of Regents of the University of Oklahoma
    Inventors: Thomas D. Schmittgen, Daniel J. Brackett
  • MICRORNA EXPRESSION PROFILE ASSOCIATED WITH PANCREATIC CANCER
    Publication number: 20100286232
    Abstract: Methods are provided for diagnosing whether a subject has, or is at risk of developing, pancreatic cancer. The methods include measuring the level of at least one miR gene product in a biological sample derived from the subject's pancreas. An alteration in the level of the miR gene product in the biological sample as compared to the level of a corresponding miR gene product in a control sample, is indicative of the subject either having, or being at risk for developing, pancreatic cancer.
    Type: Application
    Filed: March 2, 2007
    Publication date: November 11, 2010
    Applicant: The Ohio State University
    Inventors: Thomas D. Schmittgen, Daniel J. Brackett
  • IDENTIFICATION OF BIOMARKERS IN BIOLOGICAL SAMPLES AND METHODS OF USING SAME
    Publication number: 20090159793
    Abstract: The present invention is directed to methods of identifying biomarkers in liquid biological samples obtained from cancer patients or patients exhibiting a disease state. Such methods may include the use of electrospray ionization-time of flight mass spectrometry (ESI-TOF MS).
    Type: Application
    Filed: December 22, 2008
    Publication date: June 25, 2009
    Inventors: Jay S. Hanas, James R. Hocker, Daniel J. Brackett, Russell G. Postier, Marvin D. Peyton, John Y. Cheung
  • Method and composition for the treatment of septic shock
    Patent number: 5650392
    Abstract: The present invention contemplates a composition and method for treating septic shock in a mammal or as a prophylactic treatment prior to a surgical procedure, comprising administering a therapeutically effective amount of a bacterial lipopolysaccharide binding peptide derived from CAP37 protein. In a preferred version, the composition and method of use may comprise a peptide comprising amino acids 20-44 of CAP37 or a subunit thereof.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: July 22, 1997
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Heloise Anne Pereira, Daniel J. Brackett, Megan R. Lerner
  • Method and composition for the treatment of septic shock
    Patent number: 5607916
    Abstract: The present invention contemplates a composition and method for treating septic shock in a mammal or as a prophylactic treatment prior to a surgical procedure, comprising administering a therapeutically effective amount of a bacterial lipopolysaccharide binding peptide derived from CAP37 protein. In a preferred version, the composition and method of use may comprise a peptide comprising amino acids 20-44 of CAP37 or a subunit thereof.
    Type: Grant
    Filed: April 29, 1994
    Date of Patent: March 4, 1997
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Heloise A. Pereira, Daniel J. Brackett, Megan R. Lerner