Patents by Inventor Daniel J. Coady
Daniel J. Coady has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150037390Abstract: Cationic, anionic, and/or zwitterionic bis-urea compounds self-assemble by non-covalent interactions in aqueous solution to form high aspect ratio nanofibers. The nanofibers reversibly bind drugs by non-covalent interactions, forming drug compositions for exhibiting sustained release of the drug.Type: ApplicationFiled: August 1, 2013Publication date: February 5, 2015Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Daniel J. Coady, Richard A. Dipietro, Amanda C. Engler, James L. Hedrick, Shao Qiong Liu, Hareem T. Maune, Alshakim Nelson, Jed W. Pitera, Shrinivas Venkataraman, Yi Yan Yang
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Publication number: 20140301967Abstract: Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi.Type: ApplicationFiled: April 9, 2013Publication date: October 9, 2014Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Willy Chin, Daniel J. Coady, Richard A. Dipietro, Amanda C. Engler, James L. Hedrick, Ashlynn L. Z. Lee, Victor W. L. Ng, Zhan-Yuin Ong, Yi Yan Yang
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Patent number: 8846851Abstract: A salt catalyst comprises an ionic complex of i) a nitrogen base comprising one or more guanidine and/or amidine functional groups, and ii) an oxoacid comprising one or more active acid groups, the active acid groups independently comprising a carbonyl group (C?O), sulfoxide group (S?O), and/or a phosphonyl group (P?O) bonded to one or more active hydroxy groups; wherein a ratio of moles of the active hydroxy groups to moles of the guanidine and/or amidine functional groups is greater than 0 and less than 2.0. The salt catalysts are capable of catalyzing ring opening polymerization of cyclic carbonyl compounds.Type: GrantFiled: February 20, 2013Date of Patent: September 30, 2014Assignee: International Business Machines CorporationInventors: Daniel J. Coady, Kazuki Fukushima, James L. Hedrick, Hans W. Horn, Julia E. Rice
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Patent number: 8802074Abstract: Polymeric compounds containing polymer backbones functionalized with ion-specific recognition elements and methods for the use of these compounds are described herein. The polymeric compounds may contain multiple types of ion-specific recognition elements depending on a specific application. The polymeric compounds can be used to remove ionic species from a solution, for example, in separations applications in which a single or multiple types of ionic species are desired to be removed from the solution.Type: GrantFiled: November 23, 2009Date of Patent: August 12, 2014Assignee: Board of Regents, The University of Texas SystemInventors: Jonathan L. Sessler, Christopher W. Bielawski, Abdullah Aydogan, Daniel J. Coady
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Publication number: 20140220093Abstract: A cationic star polymer is disclosed of the general formula (1): wherein w? is a positive number greater than or equal to 3, I? is a dendritic polyester core covalently linked to w? independent peripheral linear cationic polymer chains P?. Each of the chains P? comprises a cationic repeat unit comprising i) a backbone functional group selected from the group consisting of aliphatic carbonates, aliphatic esters, aliphatic carbamates, aliphatic ureas, aliphatic thiocarbamates, aliphatic dithiocarbonates, and combinations thereof, and ii) a side chain comprising a quaternary amine group. The quaternary amine group comprises a divalent methylene group directly covalently linked to i) a positive charged nitrogen and ii) an aromatic ring.Type: ApplicationFiled: April 5, 2014Publication date: August 7, 2014Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Daniel J. Coady, Amanda C. Engler, Kazuki Fukushima, James L. Hedrick, Jeremy P. K. Tan, Yi Yan Yang
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Publication number: 20140138863Abstract: A method of preparing particles comprises forming by optical lithography a topographic template layer disposed on a surface of a substrate, which is suitable for spin casting. The template layer comprises a non-crosslinked template polymer having a pattern of independent wells therein for molding independent particles. Spin casting a particle-forming composition onto the template layer forms a composite layer comprising the template polymer and the particles disposed in the wells. The composite layer is removed from the substrate using a stripping agent that dissolves the template polymer without dissolving the particles. The particles are then isolated.Type: ApplicationFiled: November 18, 2012Publication date: May 22, 2014Applicant: International Business Machines CorporationInventors: Joy Cheng, Daniel J. Coady, Matthew E. Colburn, Blake W. Davis, James L. Hedrick, Steven J. Holmes, Hareem T. Maune, Alshakim Nelson
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Patent number: 8703197Abstract: A branched polyamine comprises about 45 to about 70 backbone tertiary amine groups, about 90 to about 140 backbone secondary amine groups, a positive number n? greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): wherein (n?+q) is a number equal to about 45 to about 70, the starred bond of formula (2) is linked to a backbone nitrogen of the branched polyamine, L? is a divalent radical comprising 3 to 30 carbons, and q/(n?+q)×100% equals about 9% to about 47%.Type: GrantFiled: September 13, 2012Date of Patent: April 22, 2014Assignees: International Business Machines Corporation, Agency for Science, Technology and ResearchInventors: Wei Cheng, Daniel J. Coady, Amanda C. Engler, James L. Hedrick, Pei Yun Teo, Chuan Yang, Yi Yan Yang
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Publication number: 20140080215Abstract: A branched polyamine comprises about 45 to about 70 backbone tertiary amine groups, about 90 to about 140 backbone secondary amine groups, a positive number n? greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): wherein (n?+q) is a number equal to about 45 to about 70, the starred bond of formula (2) is linked to a backbone nitrogen of the branched polyamine, L? is a divalent radical comprising 3 to 30 carbons, and q/(n?+q)×100% equals about 9% to about 47%.Type: ApplicationFiled: September 13, 2012Publication date: March 20, 2014Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Wei Cheng, Daniel J. Coady, Amanda C. Engler, James L. Hedrick, Pei Yun Teo, Chuan Yang, Yi Yan Yang
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Publication number: 20140073048Abstract: A branched polyamine comprises about 8 to about 12 backbone tertiary amine groups, about 18 to about 24 backbone secondary amine groups, a positive number n? greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): wherein (n?+q) is a number equal to about 8 to about 12, the starred bond of formula (2) is linked to a backbone nitrogen of the branched polyamine, L? is a divalent linking group comprising 3 to 30 carbons, and q/(n?+q)×100% equals about 9% to about 40%.Type: ApplicationFiled: September 13, 2012Publication date: March 13, 2014Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Wei Cheng, Daniel J. Coady, Amanda C. Engler, James L. Hedrick, Pei Yun Teo, Chuan Yang, Yi Yan Yang
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Patent number: 8633296Abstract: A composite hydrogel comprises an amphiphilic triblock copolymer (ABA) and a loaded micelle bound by noncovalent interactions. The loaded micelle comprises a biologically active substance and an amphiphilic diblock copolymer (CD). The A blocks comprise a steroidal repeat unit (repeat unit 1) having both a backbone carbonate and a side chain bearing a steroid functional group. Each of the A blocks has a degree of polymerization of about 0.5 to about 4.0. The B block comprises a first poly(alkylene oxide) backbone. The C block comprises a second poly(alkylene oxide) backbone. The D block comprises a steroidal repeat unit (repeat unit 2) having both a backbone carbonate group and a side chain comprising a steroid functional group. The composite hydrogel is capable of controlled release of the biologically active substance.Type: GrantFiled: September 12, 2012Date of Patent: January 21, 2014Assignees: International Business Machines Corporation, Agency for Science, Technology and ResearchInventors: Daniel J. Coady, Richard A. DiPietro, Amanda C. Engler, James L. Hedrick, Ashlynn L. Lee, Shrinivas Venkataraman, Yi Yan Yang
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Patent number: 8574815Abstract: The invention concerns a method for patterning a surface of a material. A substrate having a polymer film thereon is provided. The polymer is a selectively reactive polymer (e.g., thermodynamically unstable): it is able to unzip upon suitable stimulation. A probe is used to create patterns on the film. During the patterning, the film is locally stimulated for unzipping polymer chains. Hence, a basic idea is to provide a stimulus to the polymeric material, which in turn spontaneously decomposes e.g., into volatile constituents. For example, the film is thermally stimulated in order to break a single bond in a polymer chain, which is sufficient to trigger the decomposition of the entire polymer chain.Type: GrantFiled: August 9, 2012Date of Patent: November 5, 2013Assignee: International Business Machines CorporationInventors: Daniel J. Coady, Urs T. Duerig, Jane E. Frommer, Kazuki Fukushima, James L. Hedrick, Armin W. Knoll
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Patent number: 8450043Abstract: The invention concerns a method for patterning a surface of a material. A substrate having a polymer film thereon is provided. The polymer is a selectively reactive polymer (e.g., thermodynamically unstable): it is able to unzip upon suitable stimulation. A probe is used to create patterns on the film. During the patterning, the film is locally stimulated for unzipping polymer chains. Hence, a basic idea is to provide a stimulus to the polymeric material, which in turn spontaneously decomposes e.g., into volatile constituents. For example, the film is thermally stimulated in order to break a single bond in a polymer chain, which is sufficient to trigger the decomposition of the entire polymer chain.Type: GrantFiled: September 30, 2010Date of Patent: May 28, 2013Assignee: International Business Machines CorporationInventors: Daniel J. Coady, Urs T. Duerig, Jane E. Frommer, Kazuki Fukushima, James L. Hedrick, Armin W. Knoll
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Publication number: 20120301672Abstract: The invention concerns a method for patterning a surface of a material. A substrate having a polymer film thereon is provided. The polymer is a selectively reactive polymer (e.g., thermodynamically unstable): it is able to unzip upon suitable stimulation. A probe is used to create patterns on the film. During the patterning, the film is locally stimulated for unzipping polymer chains. Hence, a basic idea is to provide a stimulus to the polymeric material, which in turn spontaneously decomposes e.g., into volatile constituents. For example, the film is thermally stimulated in order to break a single bond in a polymer chain, which is sufficient to trigger the decomposition of the entire polymer chain.Type: ApplicationFiled: August 9, 2012Publication date: November 29, 2012Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Daniel J. Coady, Urs T. Duerig, Jane E. Frommer, Kazuki Fukushima, James L. Hedrick, Armin W. Knoll
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Publication number: 20120297905Abstract: The invention concerns a method for patterning a surface of a material. A substrate having a polymer film thereon is provided. The polymer is a selectively reactive polymer (e.g., thermodynamically unstable): it is able to unzip upon suitable stimulation. A probe is used to create patterns on the film. During the patterning, the film is locally stimulated for unzipping polymer chains. Hence, a basic idea is to provide a stimulus to the polymeric material, which in turn spontaneously decomposes e.g., into volatile constituents. For example, the film is thermally stimulated in order to break a single bond in a polymer chain, which is sufficient to trigger the decomposition of the entire polymer chain.Type: ApplicationFiled: August 9, 2012Publication date: November 29, 2012Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Daniel J. Coady, Urs T. Duerig, Jane E. Frommer, Kazuki Fukushima, James L. Hedrick, Armin W. Knoll
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Publication number: 20120251607Abstract: A composition of matter comprises a cationic polymer comprising a polycarbonate chain fragment, the polycarbonate chain fragment comprising a repeat unit comprising a side chain moiety containing a quaternary amine group; and a non-charged polymer comprising a polyester chain segment and a poly(alkylene oxide) chain segment; wherein i) the cationic polymer and the non-charged polymer are amphiphilic and biocompatible, ii) the cationic polymer and the non-charged polymer form a mixed complex by non-covalent interactions in water, and iii) the mixed complex is a more effective antimicrobial agent against at least a Gram-negative microbe compared to the cationic polymer and the non-charged polymer alone when tested using otherwise identical conditions.Type: ApplicationFiled: March 31, 2011Publication date: October 4, 2012Inventors: Daniel J. Coady, Kazuki Fukushima, James L. Hedrick, Yi Yan Yang
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Publication number: 20120082944Abstract: The invention concerns a method for patterning a surface of a material. A substrate having a polymer film thereon is provided. The polymer is a selectively reactive polymer (e.g., thermodynamically unstable): it is able to unzip upon suitable stimulation. A probe is used to create patterns on the film. During the patterning, the film is locally stimulated for unzipping polymer chains. Hence, a basic idea is to provide a stimulus to the polymeric material, which in turn spontaneously decomposes e.g., into volatile constituents. For example, the film is thermally stimulated in order to break a single bond in a polymer chain, which is sufficient to trigger the decomposition of the entire polymer chain.Type: ApplicationFiled: September 30, 2010Publication date: April 5, 2012Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Daniel J. Coady, Urs T. Duerig, Jane E. Frommer, Kazuki Fukushima, James L. Hedrick, Armin W. Knoll
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Publication number: 20100129308Abstract: Polymeric compounds containing polymer backbones functionalized with ion-specific recognition elements and methods for the use of these compounds are described herein. The polymeric compounds may contain multiple types of ion-specific recognition elements depending on a specific application. The polymeric compounds can be used to remove ionic species from a solution, for example, in separations applications in which a single or multiple types of ionic species are desired to be removed from the solution.Type: ApplicationFiled: November 23, 2009Publication date: May 27, 2010Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Jonathan L. Sessler, Christopher W. Bielawski, Abdullah Aydogan, Daniel J. Coady