Abstract: Systems and methods for removal of clot material from vessel lumens are disclosed. A thrombectomy system can include a tubular member having a proximal end region configured to be disposed extracorporeally and a distal end region configured to be disposed at an intravascular treatment site at or adjacent to a thrombus. The tubular member has a sidewall defining a lumen extending therethrough from the proximal end region to the distal end region. The sidewall has an opening in the distal end region, the opening including a proximal portion spanning a first width and a distal portion spanning a second width greater than the first width. The thrombectomy system can additionally include a suction source configured to be fluidically coupled to the lumen.

Abstract: A guidewire comprising: a core wire; an elongated member extending along a longitudinal axis and defining: an inner surface defining an inner lumen, a plurality of openings disposed along the elongated member, each opening extending from an outer surface of the elongated member towards the inner surface, a first locking recess extending through the elongated member from the outer surface to the inner surface, a second locking recess extending from the inner surface towards a second location on the outer surface, wherein the first locking recess and the second locking recess defines a locking channel; and a locking element disposed within the locking channel and affixed to the elongated member, the locking element defining an aperture configured to receive the core wire, wherein the locking element is configured to inhibit unintended proximal movement of the core wire along the longitudinal axis relative to the elongated member.

Abstract: A medical device comprising: an elongated body extending along a longitudinal axis from a proximal end to a distal end, wherein the elongated body comprises a plurality of interconnecting struts extending around an outer perimeter of the elongated body and defining a plurality of openings, wherein the plurality of interconnecting struts comprises: a plurality of helical struts extending along the elongated body and defining one or more coils extending around the outer perimeter of the elongated body, a plurality of first cross struts extending between longitudinally adjacent coils of the one or more coils, and a plurality of second cross struts extending between first cross struts and coils of the plurality of helical struts, wherein each opening is defined by two or more struts, and an outer coating disposed on the outer surface of the elongated body.

Abstract: A guidewire including: a core wire defining a longitudinal axis; and an elongated body extending along the longitudinal axis. The elongated body defines a plurality of openings between a distal end of the elongated body and a proximal end of the elongated body, wherein each opening of the plurality of openings defines an arc extending from a first end to a second end, wherein a center of the arc is longitudinally offset from the first and second ends. The plurality of openings includes: a first group of openings disposed around a perimeter of the elongated body; and a second group of openings disposed around the perimeter, wherein each opening of the second group of openings is longitudinally adjacent to and is a mirror image of a respective opening of the first group of openings relative to a plane normal to the longitudinal axis.

Abstract: A guidewire comprising: a core wire defining a longitudinal axis; and an elongated body extending along the longitudinal axis, the elongated body defining: an inner lumen configured to retain a distal portion of the core wire and a plurality of openings, wherein each opening of the plurality of openings defines an arc defining a radius of curvature and a concave portion facing a distal end of the elongated body or a proximal end of the elongated body, and wherein the radii of curvature of the plurality of openings varies along the longitudinal axis.

Abstract: A device for intravascular intervention can comprise an interventional element, an elongate manipulation member having a retention portion, and a joining element. The elongate element can comprise a distally located attachment portion. The interventional element includes a proximal end portion with a hole therethrough, the attachment portion of the elongate member extending through the hole at the bend such that first and second segments of the elongate member each extend proximally from the hole. A retention portion includes an arm extends proximally of the hole and a shoulder protruding radially outwardly from a proximal portion of the arm. A joining element circumferentially surrounds at least a portion of the retention portion and at least a portion of the first and second segments of the elongate member such that a proximal end of the joining element is positioned distal to the shoulder of the retention portion.

Abstract: A device for intravascular intervention can comprise an interventional element, an elongate manipulation member having a retention portion, and a joining element. The elongate element can comprise a distally located attachment portion. The interventional element includes a proximal end portion with a hole therethrough, the attachment portion of the elongate member extending through the hole at the bend such that first and second segments of the elongate member each extend proximally from the hole. A retention portion includes an arm extends proximally of the hole and a shoulder protruding radially outwardly from a proximal portion of the arm. A joining element circumferentially surrounds at least a portion of the retention portion and at least a portion of the first and second segments of the elongate member such that a proximal end of the joining element is positioned distal to the shoulder of the retention portion.

Abstract: The present disclosure relates generally to the field of variable geometry guide vanes for gas turbine engines. More specifically, the present disclosure relates to a plastic variable inlet guide vane for a gas turbine engine.

Abstract: The present disclosure relates generally to the field of variable geometry guide vanes for gas turbine engines. More specifically, the present disclosure relates to a plastic variable inlet guide vane for a gas turbine engine.