Abstract: Systems and methods for controlling the position of a user of a wearable positional therapy device are provided. The wearable position therapy device can be configured to monitor and store physiological signals that can be used to assess sleep quality and sleeping position of a user. The device can be configured to be worn around the head, the neck, or body of the user. The device can be configured to provide feedback to a user if the user is sleeping or is positioned in a target position to induce the user to change positions. The feedback can be provided by one or more haptic motors that can be configured to provide various levels of feedback and the level of feedback can be customized based on the user's reaction to the feedback.

Abstract: An efficient, objective, flexible and easily deployable system for conducting evaluations of mental and physiological state and recommending individualized treatment to improve said state is described. The method and system are based on commensurate measurement of mental functions, levels of stress and anxiety, and/or biologically active molecules such as neurotransmitters, immune markers including cytokines and hormones. The method and system are designed to assess an individual's cognitive function and the underlying physiology in order to delineate various disease processes, injuries, drug states, training stages, fatigue levels, stress levels, aging processes, predict susceptibility to stress and/or sleep deprivation, identify aptitude for training and/or characterize effects of any experimental conditions.

Abstract: A method and apparatus for assessment of hemodynamic and functional state of the brain is disclosed. In one embodiment, the method and apparatus includes non-invasive measurement of intracranial pressure, assessment of the brain's electrical activity, and measurement of cerebral blood flow. In some embodiments, the method and apparatus include measuring the volume change in the intracranial vessels with a near-infrared spectroscopy or other optical method, measuring the volume change in the intracranial vessels with rheoencephalography or other electrical method, and measuring the brain's electrical activity using electroencephalography.

Abstract: Systems and methods for assessment of sleep quality in adults and children are provided. These techniques include an apparatus worn above the forehead containing the circuitry for collecting and storing physiological signals. The apparatus integrates with a sensor strip and a nasal mask to obtain the physiological signals for the user. The form factor of this apparatus is comfortable, easy to self-apply, and results in less data artifacts than conventional techniques for capturing physiological data for analyzing sleep quality. Neuro-respiratory signals are analyzed using means to extract more accurate definitions of the frequency and severity of sleep discontinuity, sleep disordered breathing and patterns of sleep architecture. Biological biomarkers and questionnaire responses can also be compared to a database of healthy and chronically diseased patients to provide a more accurate differential diagnosis and to help determine the appropriate disease management recommendations.

Abstract: Photoplethysmography (PPG) is obtained using one red (e.g., 660 nm) and one infrared (e.g., 880 to 940 nm) light emitting diode with a single photo diode in combination with a pressure transducer thereby allowing both CVP and SpO2 to be measured simultaneously. The system also includes sensors capable of measuring position, angle and/or movement of the sensor or patient. Once the PPG signal is acquired, high pass adaptive and/or notch filtering can be used with one element of the filter from the red and infrared signals used to measure the arterial changes needed to compute SpO2 and the other element of the signal can be used to measure CVP changes.

Abstract: Photoplethysmography (PPG) is obtained using one red (e.g., 660 nm) and one infrared (e.g., 880 to 940 nm) light emitting diode with a single photo diode in combination with a pressure transducer thereby allowing both CVP and SpO2 to be measured simultaneously. The system also includes sensors capable of measuring position, angle and/or movement of the sensor or patient. Once the PPG signal is acquired, high pass adaptive and/or notch filtering can be used with one element of the filter from the red and infrared signals used to measure the arterial changes needed to compute SpO2 and the other element of the signal can be used to measure CVP changes.

Abstract: A system for predicting risk for perioperative complications is described including a user device for receiving a set of risk factors to determine perioperative complications for a patient including patient data useful to determine the likelihood of obstructive sleep apnea. The system also includes an acquisition module to receive data from an obstructive sleep apnea sleep study of the patient. Further a determination module can determine the severity of obstructive sleep apnea for the patient. The system can also include an analysis module having a predictive model that incorporates one or more prediction equations for predicting perioperative complications derived from one or more databases having multiple patient data relevant to predict perioperative complications.

Abstract: In a technique for collecting and analyzing physiological signals to detect sleep apnea, a small light-weight physiological monitoring system, affixed to a patient's forehead, detects and records the pulse, oximetry, snoring sounds, and head position of a patient to detect a respiratory event, such as sleep apnea. The physiological monitoring system may contain several sensors including a pulse oximeter to detect oximetry and pulse rate, a microphone to detect snoring sounds, and a position sensor to detect head position. The physiological monitoring system also can contain a memory to store or record the signals monitored by the mentioned sensors and a power source. The physiological monitoring system may be held in place by a single elastic strap, thereby enabling a patient to use the system without the assistance of trained technicians.

Abstract: In a technique for collecting and analyzing physiological signals to detect sleep apnea, a small light-weight physiological monitoring system, affixed to a patient's forehead, detects and records the pulse, oximetry, snoring sounds, and head position of a patient to detect a respiratory event, such as sleep apnea. The physiological monitoring system may contain several sensors including a pulse oximeter to detect oximetry and pulse rate, a microphone to detect snoring sounds, and a position sensor to detect head position. The physiological monitoring system also can contain a memory to store or record the signals monitored by the mentioned sensors and a power source. The physiological monitoring system may be held in place by a single elastic strap, thereby enabling a patient to use the system without the assistance of trained technicians.

Abstract: The EEG electrode and EEG electrode locator assembly may be used in combination with an EEG electrode locator headgear including a plurality of locator straps connectable to one or more of the EEG electrode locators that form an electrode locator assembly with the EEG electrode, for accurately positioning one or more of the EEG electrodes relative to the user's scalp, and for biasing the plurality of electrodes toward the user's scalp. The EEG electrode is adapted to be received in and cooperate with an EEG electrode locator ring, to form the electrode locator assembly. The EEG electrode includes a dispenser assembly adapted to dispense an electrically conductive gel onto the user's scalp to prepare the user's scalp.

Abstract: The method for the quantification of EEG waveforms along the alertness continuum involves collecting and transforming EEG signal data, identifying and rejecting or decontaminating epochs containing various artifacts, and classifying individual EEG patterns along an alertness-drowsiness continuum. The results of the multi-level classification system are applied in real-time to provide feedback to the user via an audio or visual alarm, or are recorded for subsequent off-line analysis.

Abstract: The method for the quantification of EEG waveforms along the alertness continuum involves collecting and transforming EEG signal data, identifying and rejecting or decontaminating epochs containing various artifacts, and classifying individual EEG patterns along an alertness-drowsiness continuum. The results of the multi-level classification system are applied in real-time to provide feedback to the user via an audio or visual alarm, or are recorded for subsequent off-line analysis.

Abstract: The method for the quantification of EEG waveforms along the alertness continuum involves collecting and transforming EEG signal data, identifying and rejecting or decontaminating epochs containing various artifacts, and classifying individual EEG patterns along an alertness-drowsiness continuum. The results of the multi-level classification system are applied in real-time to provide feedback to the user via an audio or visual alarm, or are recorded for subsequent off-line analysis.

Abstract: In a technique for collecting and analyzing physiological signals to detect sleep apnea, a small light-weight physiological monitoring system, affixed to a patient's forehead, detects and records the pulse, oximetry, snoring sounds, and head position of a patient to detect a respiratory event, such as sleep apnea. The physiological monitoring system may contain several sensors including a pulse oximeter to detect oximetry and pulse rate, a microphone to detect snoring sounds, and a position sensor to detect head position. The physiological monitoring system also can contain a memory to store or record the signals monitored by the mentioned sensors and a power source. The physiological monitoring system may be held in place by a single elastic strap, thereby enabling a patient to use the system without the assistance of trained technicians.

Abstract: The EEG electrode locator headgear allows the user to locate and apply disposable EEG electrodes accurately according to the International 10/20 System without technical assistance, to allow the acquisition of high quality EEG signals. The headgear includes a front forehead pad, a base strap assembly connected to the front forehead pad, a plurality of EEG electrode locators for receiving EEG electrodes, and a plurality of locator straps connected to the front pad of material, the base strap assembly, and to the plurality of EEG electrode locators for accurately positioning the plurality of EEG electrode locators positioned relative to the scalp of a user. A visor can be attached to the front pad of material, and the base strap assembly may include an occipital locator device. A plunger assembly with spreadable fingers for optionally parting the hair of the user's scalp is also provided that is inserted in the electrode locators to optionally prepare the user's scalp and to seat the electrodes.

Abstract: The EEG electrode locator headgear allows the user to locate and apply disposable EEG electrodes accurately according to the International 10/20 System without technical assistance, to allow the acquisition of high quality EEG signals. The headgear includes a front forehead pad, a base strap assembly connected to the front forehead pad, a plurality of EEG electrode locators for receiving EEG electrodes, and a plurality of locator straps connected to the front pad of material, the base strap assembly, and to the plurality of EEG electrode locators for accurately positioning the plurality of EEG electrode locators positioned relative to the scalp of a user. A visor can be attached to the front pad of material, and the base strap assembly may include an occipital locator device. A plunger assembly with spreadable fingers for optionally parting the hair of the user's scalp is also provided that is inserted in the electrode locators to optionally prepare the user's scalp and to seat the electrodes.

Abstract: The EEG electrode and EEG electrode locator assembly may be used in combination with an EEG electrode locator headgear including a plurality of locator straps connectable to one or more of the EEG electrode locators that form an electrode locator assembly with the EEG electrode, for accurately positioning one or more of the EEG electrodes relative to the user's scalp, and for biasing the plurality of electrodes toward the user's scalp. The EEG electrode is adapted to be received in and cooperate with an EEG electrode locator ring, to form the electrode locator assembly. The EEG electrode includes a dispenser assembly adapted to dispense an electrically conductive gel onto the user's scalp to prepare the user's scalp.

Abstract: The EEG electrode locator headgear allows the user to locate and apply disposable EEG electrodes accurately according to the International 10/20 System without technical assistance, to allow the acquisition of high quality EEG signals. The headgear includes a front forehead pad, a base strap assembly connected to the front forehead pad, a plurality of EEG electrode locators for receiving EEG electrodes, and a plurality of locator straps connected to the front pad of material, the base strap assembly, and to the plurality of EEG electrode locators for accurately positioning the plurality of EEG electrode locators positioned relative to the scalp of a user. A visor can be attached to the front pad of material, and the base strap assembly may include an occipital locator device. A plunger assembly with spreadable fingers for parting the hair of the scalp of the user is also provided that is inserted in the electrode locators to prepare the scalp of the user and to seat the electrodes.