Patents by Inventor Daniel J. Medina

Daniel J. Medina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPIES FOR TREATMENT OF CANCER
    Publication number: 20240075160
    Abstract: Provided herein are methods of treating cancer in a human subject, comprising administering to the subject: i) an antibody-drug conjugate (ADC) comprising an antibody, a cleavable linker and a cytotoxic agent, and ii) a bispecific checkpoint inhibitor. Further provided herein are kits comprising i) an antibody-drug conjugate (ADC) comprising an antibody, a cleavable linker and a cytotoxic agent, and ii) a bispecific checkpoint inhibitor.
    Type: Application
    Filed: July 27, 2023
    Publication date: March 7, 2024
    Inventors: Bilal OMAR, Scott A. HAMMOND, Judith ANDERTON, Nadia LUHESHI, Daniel J. FREEMAN, Krista KINNEER, Jorge ZERON-MEDINA CUAIRAN, Ikbel ACHOUR, Doug PALMER
  • BMI-1 protein expression modulators
    Patent number: 8680113
    Abstract: Compounds having Formula I: wherein the variables Ar1, Ar2, R1, R2 and R3 are defined herein, pharmaceutical compositions, and methods of using such compounds or compositions for inhibiting Bmi-1 expression.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: March 25, 2014
    Assignee: PTC Therapeutics, Inc.
    Inventors: Young-Choon Moon, Nadiya Sydorenko, Thomas Davis, Liangxian Cao, Daniel J. Medina, Marites A. Rafanan
  • BMI-1 PROTEIN EXPRESSION MODULATORS
    Publication number: 20110190239
    Abstract: The compounds, pharmaceutical compositions, and methods of using such compounds or compositions thereof described herein are useful for treating a disease modulated by B-cell specific Moloney murine leukemia virus integration site 1 (Bmi-1) protein expression.
    Type: Application
    Filed: July 1, 2009
    Publication date: August 4, 2011
    Applicant: PTC THERAPEUTICS, INC.
    Inventors: Young-Choon Moon, Nadiya Sydorenko, Thomas Davis, Liangxian Cao, Daniel J. Medina, Marites A. Rafanan