Patents by Inventor Daniel J. Sexton

Daniel J. Sexton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY
    Publication number: 20140107041
    Abstract: The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<1 ?M), and dimer and multimeric constructs comprising these polypeptides.
    Type: Application
    Filed: September 5, 2013
    Publication date: April 17, 2014
    Applicant: DYAX CORP.
    Inventors: AARON K. SATO, DANIEL J. SEXTON, DANIEL T. DRANSFIELD, ROBERT CHARLES LADNER, CHRISTOPHE ARBOGAST, PHILIPPE BUSSAT, HONG FAN, SUDHA KHURANA, KAREN E. LINDER, EDMUND R. MARINELLI, PALANIAPPA NANJAPPAN, ADRIAN NUNN, RADHAKRISHNA PILLAI, SYBILLE POCHON, KONDAREDDIAR RAMALINGAM, AJAY SHRIVASTAVA, BO SONG, ROLF E. SWENSON, MATTHEW A. VON WRONSKI
  • KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
    Patent number: 8642010
    Abstract: The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<1 ?M), and dimer and multimeric constructs comprising these polypeptides.
    Type: Grant
    Filed: June 8, 2009
    Date of Patent: February 4, 2014
    Assignees: Dyax Corp., Bracco Suisse SA
    Inventors: Aaron K. Sato, Daniel J. Sexton, Daniel T. Dransfield, Robert C. Ladner, Christophe Arbogast, Philippe Bussat, Hong Fan, Sudha Khurana, Karen E. Linder, Edmund R. Marinelli, Palaniappa Nanjappan, Adrian D. Nunn, Radhakrishna K. Pillai, Sibylle Pochon, Feng Yan, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf E. Swenson, Mathew A. Von Wronski
  • PLASMA KALLIKREIN BINDING PROTEINS
    Publication number: 20120201756
    Abstract: Plasma kallikrein binding proteins and methods of using such proteins are described.
    Type: Application
    Filed: January 6, 2012
    Publication date: August 9, 2012
    Applicant: DYAX CORP.
    Inventor: Daniel J. Sexton
  • HK1-BINDING PROTEINS
    Publication number: 20120027686
    Abstract: The invention features hK1 binding polypeptides as well as compositions comprising such polypeptides and methods of making and using such polypeptides.
    Type: Application
    Filed: July 28, 2011
    Publication date: February 2, 2012
    Applicant: DYAX CORP.
    Inventors: Daniel J. Sexton, Andrew Nixon, Anthony Williams, Robert C. Ladner, Qi-Long Wu
  • PLASMA KALLIKREIN BINDING PROTEINS
    Publication number: 20110200611
    Abstract: Plasma kallikrein binding proteins and methods of using such proteins are described.
    Type: Application
    Filed: January 6, 2011
    Publication date: August 18, 2011
    Applicant: DYAX CORP.
    Inventor: Daniel J. Sexton
  • HK1-binding proteins
    Patent number: 7993646
    Abstract: The invention features hK1 binding polypeptides as well as compositions comprising such polypeptides and methods of making and using such polypeptides.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: August 9, 2011
    Assignee: Dyax Corp.
    Inventors: Daniel J. Sexton, Andrew Nixon, Anthony Williams, Robert C. Ladner, Qi-Long Wu
  • KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY
    Publication number: 20100003195
    Abstract: The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<1 ?M), and dimer and multimeric constructs comprising these polypeptides.
    Type: Application
    Filed: June 8, 2009
    Publication date: January 7, 2010
    Inventors: Aaron K. Sato, Daniel J. Sexton, Daniel T. Dransfield, Robert C. Ladner, Christophe Arbogast, Philippe Bussat, Hong Fan, Sudha Khurana, Karen E. Linder, Edmund R. Marinelli, Palaniappa Nanjappan, Adrian D. Nunn, Radhakrishna Pillai, Sibylle Pochon, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf E. Swenson, Mathew A. Von Wronski
  • HK1-BINDING PROTEINS
    Publication number: 20080213251
    Abstract: The invention features hK1 binding polypeptides as well as compositions comprising such polypeptides and methods of making and using such polypeptides.
    Type: Application
    Filed: December 14, 2007
    Publication date: September 4, 2008
    Applicant: DYAX CORP.
    Inventors: Daniel J. Sexton, Andrew Nixon, Anthony Williams, Robert C. Ladner, Qi-Long Wu
  • Antibodies that bind hK-1
    Patent number: 7329737
    Abstract: The invention features hK1 binding polypeptides as well as compositions comprising such polypeptides and methods of making and using such polypeptides.
    Type: Grant
    Filed: August 3, 2005
    Date of Patent: February 12, 2008
    Assignee: Dyax Corp.
    Inventors: Daniel J. Sexton, Andrew Nixon, Anthony Williams, Robert C. Ladner, Qi-Long Wu