Patents by Inventor Daniel J. Shaffer
Daniel J. Shaffer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10632444Abstract: A method for processing a biological material sample includes dispensing a sample into wells of an array tape from a sample plate, dispensing a reagent into the wells of the array tape from a reagent plate, and sealing the sample and the reagent in the array tape. The method further includes cooling the array tape and detecting biological material in the wells of the array tape.Type: GrantFiled: January 13, 2014Date of Patent: April 28, 2020Assignee: DOUGLAS SCIENTIFIC, LLCInventors: Mark Whalen, Charles Gervais, Anthony Sanborn, Andrew Haug, Darren Cook, Satish Rai, Hans A. Mische, Stephen A. Judice, Daniel J. Shaffer
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Publication number: 20150352512Abstract: A method for processing a biological material sample includes dispensing a sample into wells of an array tape from a sample plate, dispensing a reagent into the wells of the array tape from a reagent plate, and sealing the sample and the reagent in the array tape. The method further includes cooling the array tape and detecting biological material in the wells of the array tape.Type: ApplicationFiled: January 13, 2014Publication date: December 10, 2015Applicant: Douglas Scientfic, LLCInventors: Mark Whalen, Charles Gervais, Anthony Sanborn, Andrew Haug, Darren Cook, Satish Rai, Hans A. Mische, Stephen A. Judice, Daniel J. Shaffer
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Publication number: 20120220478Abstract: The invention relates to methods and biomarkers for assessing a subject's risk for a disease, such as cancer, an autoimmune disease or a neurological disease. In particular, the invention provides methods and biomarkers for creating exon copy number variation (ECNV) profiles, and determining disease risk according to the subject's ECNV profiles.Type: ApplicationFiled: July 20, 2010Publication date: August 30, 2012Applicant: Bar Harbor Biotechnology, Inc.Inventor: Daniel J. Shaffer
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Patent number: 7881873Abstract: Systems and methods for performing rapid genomic DNA analysis of samples, such as control samples and experimental samples. In one aspect, the system makes use of genomic DNA input, rather than gene expression input such as mRNA and/or cDNA associated with mRNA. The systems and methods perform statistical analyses on data generated from the samples to determine which DNA sequences in an identified set of DNA sequences have a basis of variation in an experimental sample when compared to a control sample, and additionally provide a quantitative measure of this variation. The quantitative measure may be based on metrics such as copy number and/or fold-change. The systems and methods employ this statistical framework in DNA-based evaluation settings, including the evaluation/diagnosis of a pathological condition such as cancer or transgenic analysis of transgenic plants and animals.Type: GrantFiled: January 27, 2006Date of Patent: February 1, 2011Assignee: The Jackson LaboratoryInventors: Shreeram Akilesh, Kevin D. Mills, Derry Charles Roopenian, Daniel J. Shaffer
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Patent number: 7822556Abstract: Methods and applications of Global Patter Recognition (GPR), including a system for analyzing the results of real-time polymerase chain reaction (RT-PCR) experiments employing micro-titer and/or microarray plates and robotic plate readers is described. The system employs a set of self-normalizing housekeeping primers or oligonucleotides on the plates/arrays and an algorithmic approach to normalizing expression data from all primers on the plate based on the reaction products of several of the self-normalizing gene primers oligonucleotides. Normalization is accomplished using simplex reactions involving these self-normalizing primers/oligonucleotides; the normalization parameters are then useable across all control and experimental reactions of the plate/array. A ranked list of genes whose amount of change is statistically significant can be determined. The accuracy of this list is enhanced by the data normalization aspect of the system. Other applications of GPR are also disclosed herein.Type: GrantFiled: July 29, 2009Date of Patent: October 26, 2010Assignee: The Jackson LaboratoryInventors: Shreeram Akilesh, Derry Roopenian, Daniel J. Shaffer
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Publication number: 20100023272Abstract: Methods and applications of Global Patter Recognition (GPR), including a system for analyzing the results of real-time polymerase chain reaction (RT-PCR) experiments employing micro-titer and/or microarray plates and robotic plate readers is described. The system employs a set of self-normalizing housekeeping primers or oligonucleotides on the plates/arrays and an algorithmic approach to normalizing expression data from all primers on the plate based on the reaction products of several of the self-normalizing gene primers oligonucleotides. Normalization is accomplished using simplex reactions involving these self-normalizing primers/oligonucleotides; the normalization parameters are then useable across all control and experimental reactions of the plate/array. A ranked list of genes whose amount of change is statistically significant can be determined. The accuracy of this list is enhanced by the data normalization aspect of the system. Other applications of GPR are also disclosed herein.Type: ApplicationFiled: July 29, 2009Publication date: January 28, 2010Applicant: The Jackson LaboratoryInventors: Shreeram Akilesh, Derry Roopenian, Daniel J. Shaffer
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Publication number: 20020033466Abstract: A method of preparing a stable firefighting foam composition is disclosed. The method comprises combining effective amounts of a) the product of water and an alkali metal alkyl sulfate, followed by b) a fluorinated polymer, to form a final, stable mixture of materials, the foam composition being distributable on a fire.Type: ApplicationFiled: January 11, 2001Publication date: March 21, 2002Inventors: Daniel J. Shaffer, Robert E. Gensemer
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Publication number: 20020030176Abstract: A composition that produces a film forming foam for firefighting is disclosed. The composition comprises an amount, effective for the intended purpose, of a biodegradable mixture of an alkali metal sulfate, a fluorinated polymer, propylene glycol and water.Type: ApplicationFiled: January 11, 2001Publication date: March 14, 2002Inventors: Daniel J. Shaffer, Robert E. Gensemer
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Patent number: D1016059Type: GrantFiled: June 17, 2022Date of Patent: February 27, 2024Assignee: Apple Inc.Inventors: Jody Akana, Bartley K. Andre, Shota Aoyagi, Anthony Michael Ashcroft, Jeremy Bataillou, Daniel J. Coster, Daniele De Iuliis, M. Evans Hankey, Julian Hoenig, Richard P. Howarth, Jonathan P. Ive, Duncan Robert Kerr, Marc A. Newson, Matthew Dean Rohrbach, Peter Russell-Clarke, Benjamin Andrew Shaffer, Mikael Silvanto, Christopher J. Stringer, Eugene Antony Whang, Rico Zörkendörfer
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Patent number: D1019449Type: GrantFiled: May 27, 2020Date of Patent: March 26, 2024Assignee: Apple Inc.Inventors: Jody Akana, Molly Anderson, Bartley K. Andre, Shota Aoyagi, Anthony Michael Ashcroft, Jeremy Bataillou, Daniel J. Coster, Daniele De Iuliis, M. Evans Hankey, Julian Hoenig, Richard P. Howarth, Jonathan P. Ive, Duncan Robert Kerr, Marc A. Newson, Matthew Dean Rohrbach, Peter Russell-Clarke, Benjamin Andrew Shaffer, Mikael Silvanto, Christopher J. Stringer, Eugene Antony Whang, Rico Zörkendörfer
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Patent number: D1021892Type: GrantFiled: November 25, 2020Date of Patent: April 9, 2024Assignee: Apple Inc.Inventors: Jody Akana, Bartley K. Andre, Shota Aoyagi, Anthony Michael Ashcroft, Jeremy Bataillou, Daniel J. Coster, Daniele De Iuliis, M. Evans Hankey, Julian Hoenig, Richard P. Howarth, Jonathan P. Ive, Duncan Robert Kerr, Scott A. Myers, David A. Pakula, Rasamy Phouthavong, Matthew Dean Rohrbach, Peter Russell-Clarke, Benjamin Andrew Shaffer, Ashutosh Y. Shukla, Mikael Silvanto, Christopher J. Stringer, Eugene Antony Whang, Rico Zörkendörfer
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Patent number: D1022692Type: GrantFiled: June 5, 2020Date of Patent: April 16, 2024Assignee: Apple Inc.Inventors: Jody Akana, Bartley K. Andre, Shota Aoyagi, Anthony Michael Ashcroft, Jeremy Bataillou, Daniel J. Coster, Daniele De Iuliis, M. Evans Hankey, Julian Hoenig, Richard P. Howarth, Jonathan P. Ive, Duncan Robert Kerr, Matthew Dean Rohrbach, Peter Russell-Clarke, Benjamin Andrew Shaffer, Mikael Silvanto, Christopher J. Stringer, Eugene Antony Whang, Rico Zörkendörfer