Patents by Inventor Daniel J. Wackelin

Daniel J. Wackelin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diverse carbene transferase enzyme catalysts derived from a P450 enzyme
    Patent number: 11525123
    Abstract: The present disclosure provides cytochrome P450 variants useful for carrying out in vivo and in vitro carbene insertion reactions. Methods for preparing carbene insertion products including cyclopropenes, cyclopropanes, bicyclobutanes, substituted lactones, cyclized compounds, and substituted amines are also described.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: December 13, 2022
    Assignee: California Institute of Technology
    Inventors: Kai Chen, Noah P. Dunham, Daniel J. Wackelin, Andrew Z. Zhou, Zhen Liu
  • DIVERSE CARBENE TRANSFERASE ENZYME CATALYSTS DERIVED FROM A P450 ENZYME
    Publication number: 20210292718
    Abstract: The present disclosure provides cytochrome P450 variants useful for carrying out in vivo and in vitro carbene insertion reactions. Methods for preparing carbene insertion products including cyclopropenes, cyclopropanes, bicyclobutanes, substituted lactones, cyclized compounds, and substituted amines are also described.
    Type: Application
    Filed: March 12, 2021
    Publication date: September 23, 2021
    Applicant: California Institute of Technology
    Inventors: Kai Chen, Noah P. Dunham, Daniel J. Wackelin, Andrew Z. Zhou, Zhen Liu