Abstract: Described herein are methods of treating cancer in a subject in need thereof comprising administering to the subject a pharmaceutical composition comprising 1-(4-(benzylamino)-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide, or a pharmaceutically acceptable salt thereof, whereby the subject experiences a therapeutic response.

Abstract: Provided herein are novel photoactive fluorescent compounds and their use in labeling proteins, for example, tagged proteins, and their use for visualizing the location and dynamics of proteins in living cells.

Abstract: Disclosed are techniques for determining network configurations through machine logic from security certificates of destination computer devices in the network. When a security component of a network receives an incoming data packet sent to a destination computer device in the network, a security certificate is requested from the destination computer device. The security component then configures a set of network rules for forwarding data packets to the destination computer device based on information in the security certificate of the destination computer device. Properties of the incoming data packet are compared to the set of network rules to determine whether to forward the incoming data packet to the destination computer.

Abstract: Disclosed are techniques for determining network configurations through machine logic from security certificates of destination computer devices in the network. When a security component of a network receives an incoming data packet sent to a destination computer device in the network, a security certificate is requested from the destination computer device. The security component then configures a set of network rules for forwarding data packets to the destination computer device based on information in the security certificate of the destination computer device. Properties of the incoming data packet are compared to the set of network rules to determine whether to forward the incoming data packet to the destination computer.

Abstract: A billing system for making reservations at an establishment and splitting the resultant bill and methods for manufacturing and using same. The billing system includes a plurality of user devices, an application server, and at least one establishment device. One embodiment includes selecting a invitee user profile for addition to a split set associated with the reservation, the split set initially comprising an organizing user profile; sending a split invitation to a invitee user device associated with the invitee user profile; receiving a split-accept notification from the invitee user device; adding the user profile to the split set; and paying the bill by paying a first portion of the bill via a first payment method associated with the invitee user profile and paying a second portion of the bill via a second payment method associated with the organizing user profile.