Patents by Inventor Daniel James Bezila

Daniel James Bezila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of refolding mammalian glycosyltransferases
    Patent number: 8822191
    Abstract: The present invention provides methods of refolding mammalian glycosyltransferases that have been produced in bacterial cells, and methods to use such refolded glycosyltransferases, including glycosyltransferase mutants that have enhanced ability to be refolded. The invention also provides methods of refolding more than one glycosyltransferase in a single vessel, methods to use such refolded glycosyltransferases, and reaction mixtures comprising the refolded glycosyltransferases.
    Type: Grant
    Filed: February 4, 2005
    Date of Patent: September 2, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Sami Saribas, David Hakes, Scott Willett, Karl F. Johnson, Daniel James Bezila, Shawn DeFrees
  • Synthesis of oligosaccharides, glycolipids, and glycoproteins using bacterial glycosyltransferases
    Patent number: 7524655
    Abstract: This invention provides nucleic acid and amino acid sequences of fucosyltransferases from Helicobactor pylori. The invention also provides methods to use the fucosyltransferases to synthesize oligosaccharides, glycoproteins, and glycolipids.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: April 28, 2009
    Assignees: Neose Technologies, Inc., Governors of the University of Alberta
    Inventors: Karl F. Johnson, Daniel James Bezila, Diane E. Taylor, Joanne Simala-Grant, David Rasko
  • fucosyltransferases
    Patent number: 7326770
    Abstract: This invention provides nucleic acid and amino acid sequences of fucosyltransferases from Helicobactor pylori. The invention also provides methods to use the fucosyltransferases to synthesize oligosaccharides, glycoproteins, and glycolipids.
    Type: Grant
    Filed: January 22, 2004
    Date of Patent: February 5, 2008
    Assignees: Neose Technologies, Inc., Governors of the University of Alberta
    Inventors: Joanne Simala-Grant, Diane Taylor, Karl F. Johnson, Daniel James Bezila