Abstract: An applicator for introducing a therapeutic substance into a body cavity of a subject in need of the therapeutic substance is provided. The applicator has the look and feel of a conventional tampon applicator but delivers a therapeutic substance. Generally, the applicator has a first outer member having a shape suitable for insertion into a body cavity of a mammal and has a dispensing end and a second end distal to the dispensing end. A second inner member is coaxially and slidably housed within the first member such that one end of the second inner member is within the first member. The applicator of the present invention also has at least one aperture located in a side wall of the outer member. The aperture is located on the side wall of the outer member between the dispensing end and the second end of the outer member.

Abstract: An applicator for introducing a therapeutic substance into a body cavity of a subject in need of the therapeutic substance is provided. The applicator has the look and feel of a conventional tampon applicator but delivers a therapeutic substance. Generally, the applicator has a first outer member having a shape suitable for insertion into a body cavity of a mammal and has a dispensing end and a second end distal to the dispensing end. A second inner member is coaxially and slidably housed within the first member such that one end of the second inner member is within the first member. The applicator of the present invention also has at least one aperture located in a side wall of the outer member. The aperture is located on the side wall of the outer member between the dispensing end and the second end of the outer member.

Abstract: A thermoplastic applicator is disclosed which exhibits accelerated breakup when immersed in water. The applicator includes a hollow, cylindrically shaped member which holds a pledget. This cylindrically shaped member is constructed of a water-soluble or water-dispersible material and has a wall with a thickness of less than about 0.05 inches (about 12.7 mm). A plurality of grooves are formed in the wall in a predetermined pattern to accelerate breakup of the applicator into small unrecognizable pieces. The grooves have a depth of between about 5 percent to 75 percent of the thickness of the wall. The deeper the grooves, the shorter the time period needed to breakup the applicator.