Patents by Inventor Daniel James Kenny

Daniel James Kenny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mass to charge ratio selective ejection from ion guide having supplemental RF voltage applied thereto
    Patent number: 9177776
    Abstract: An ion guide is disclosed wherein an axial DC voltage barrier is created at the exit of the ion guide. A primary RF voltage is applied to the electrodes in order to confine ions radially within the ion guide. A supplemental RF voltage is also applied to the electrodes. The supplemental RF voltage has a greater axial repeat length than that of the primary RF voltage. The amplitude of the supplemental RF voltage is increased with time causing ions to become unstable and gain sufficient axial kinetic energy such that the ions overcome the axial DC voltage barrier. Ions emerge axially from the ion guide in mass to charge ratio order.
    Type: Grant
    Filed: January 18, 2011
    Date of Patent: November 3, 2015
    Assignee: Micromass UK Limited
    Inventors: John Brian Hoyes, Daniel James Kenny, David Langridge
  • Ion Trap With Spatially Extended Ion Trapping Region
    Publication number: 20150294850
    Abstract: A mass or mass to charge ratio selective ion trap is disclosed which directs ions into a small ejection region. A RF voltage acts to confine ions in a first (y) direction within the ion trap. A DC or RF voltage acts to confine ions in a second (x) direction. A quadratic DC potential well acts to confine ions in a third (z) direction within the ion trap. The profile of the quadratic DC potential well progressively varies along the second (x) direction.
    Type: Application
    Filed: August 22, 2012
    Publication date: October 15, 2015
    Applicant: MICROMASS UK LIMITED
    Inventors: Kevin Giles, Martin Raymond Green, Daniel James Kenny, David J. Langridge, Jason Lee Wildgoose
  • Aperture gas flow restriction
    Patent number: 9159541
    Abstract: A mass spectrometer is disclosed comprising two vacuum chambers maintained at different pressures. The two vacuum chambers are interconnected by a differential pumping aperture. The effective area of the opening between the two vacuum chambers may be varied by rotating a disk having an aperture in front of the differential pumping aperture so as to vary the gas flow rate through the opening and between the two chambers.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: October 13, 2015
    Assignee: Micromass UK Limited
    Inventor: Daniel James Kenny
  • Fast Pushing Time of Flight Mass Spectrometer Combined With Restricted Mass to Charge Ratio Range Delivery
    Publication number: 20150287584
    Abstract: Ions having a restricted range of mass to charge ratios are transmitted to the acceleration region of a Time of Flight mass analyser. A control system applies a first extraction pulse to an acceleration electrode in order to accelerate a first group of ions into the time of flight region at a first time T1, wherein ions having the lowest mass to charge ratio in the first group of ions have a time of flight ?T1min through the time of flight region and ions having the highest mass to charge ratio in the first group of ions have a time of flight ?T1max through the time of flight region. The control system applies a second extraction pulse to the acceleration electrode at a subsequent second time T2, wherein ?T1max??T1min?T2?T1<?T1max.
    Type: Application
    Filed: May 29, 2015
    Publication date: October 8, 2015
    Inventors: Martin Raymond Green, Daniel James Kenny, Jason Lee Wildgoose
  • Ion guide coupled to MALDI ion source
    Patent number: 9136098
    Abstract: A pulsed ion source is disclosed wherein the ion source is energized one or more times to generate a first group of ions and a second group of ions. The first and second groups of ions are simultaneously transmitted through an ion guide whilst keeping the first and second groups of ions isolated from each other.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: September 15, 2015
    Assignee: Micromass UK Limited
    Inventors: Jason Lee Wildgoose, Steven Derek Pringle, Kevil Giles, Jeffery Mark Brown, Paul Murray, Daniel James Kenny
  • Curved ion guide with non mass to charge ratio dependent confinement
    Patent number: 9123518
    Abstract: A non-linear ion guide is disclosed comprising a plurality of electrodes. An ion guiding region is arranged between the electrodes, and the ion guiding region curves at least in a first direction. A DC voltage is applied to at least some of the electrodes in order to form a DC potential well which acts to confine ions within the ion guiding region in the first direction.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: September 1, 2015
    Assignee: Micromass UK Limited
    Inventors: Kevin Giles, Martin Raymond Green, Daniel James Kenny, Jason Lee Wildgoose, David. J. Langridge
  • DC ion guide for analytical filtering/separation
    Patent number: 9111654
    Abstract: An ion guide is disclosed comprising a plurality of electrodes. A first device is arranged and adapted to apply a RF voltage to at least some of the electrodes in order to form, in use, a pseudo-potential well which acts to confine ions in a first direction within the ion guide. A second device is arranged and adapted to apply a DC voltage to at least some of the electrodes in order to form, in use, a DC potential well which acts to confine ions in a second direction within the ion guide. A third device is arranged and adapted to cause ions having desired or undesired mass to charge ratios to be mass to charge ratio selectively ejected from the ion guide in the second direction.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: August 18, 2015
    Assignee: Micromass UK Limited
    Inventors: Kevin Giles, Martin Raymond Green, Daniel James Kenny, David J. Langridge, Jason Lee Wildgoose
  • Performance improvements for RF-only quadrupole mass filters and linear quadrupole ion traps with axial ejection
    Patent number: 9076640
    Abstract: A RF only quadrupole rod set mass filter or mass analyzer and a linear quadrupole ion trap with axial ejection are disclosed comprising a first pair of rod electrodes, a second pair of rod electrodes and an energy filter. The first pair of rod electrodes is longer than the second pair of rod electrodes. Ions having desired mass to charge ratios experience fringing fields at an exit region which results in the ions possessing sufficient axial kinetic energy to be transmitted by the energy filter. Other ions possess insufficient axial kinetic energy to be transmitted by the energy filter and are attenuated.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: July 7, 2015
    Assignee: Micromass UK Limited
    Inventors: David J. Langridge, Daniel James Kenny
  • Fast pushing time of flight mass spectrometer combined with restricted mass to charge ratio range delivery
    Patent number: 9048081
    Abstract: Ions having a restricted range of mass to charge ratios are transmitted to the acceleration region of a Time of Flight mass analyzer. A control system applies a first extraction pulse to an acceleration electrode in order to accelerate a first group of ions into the time of flight region at a first time T1, wherein ions having the lowest mass to charge ratio in the first group of ions have a time of flight ?T1min through the time of flight region and ions having the highest mass to charge ratio in the first group of ions have a time of flight ?T1max through the time of flight region. The control system applies a second extraction pulse to the acceleration electrode at a subsequent second time T2, wherein ?T1max??T1min?T2?T1<?T1max.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: June 2, 2015
    Assignee: Micromass UK Limited
    Inventors: Martin Raymond Green, Daniel James Kenny, Jason Lee Wildgoose
  • Mass spectrometer
    Patent number: 9006647
    Abstract: A collision or fragmentation cell is disclosed comprising a plurality of electrodes wherein a first RF voltage is applied to an upstream group of electrodes and a second different RF voltage is applied to a downstream group of electrodes. The radial confinement of parent ions entering the collision or fragmentation cell is optimized by the first RF voltage applied to the upstream group of electrodes and the radial confinement of daughter or fragment ions produced within the collision or fragmentation cell is optimized by the second different RF voltage applied to the downstream group of electrodes.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: April 14, 2015
    Assignee: Micromass UK Limited
    Inventors: Daniel James Kenny, Robert Harold Bateman, Martin Raymond Green, Jason Lee Wildgoose, Steven Derek Pringle
  • Method to Detect and Sequence Post Translationally Modified Peptides
    Publication number: 20150090876
    Abstract: A method of detecting and sequencing post translationally modified peptides is disclosed wherein a negative ion precursor scan is performed. A negative ion high resolution MS scan is then performed and then MRM channels in positive ion mode are determined and monitored. A positive ion MS/MS scan is then performed.
    Type: Application
    Filed: December 8, 2014
    Publication date: April 2, 2015
    Inventors: Christopher John Hughes, Therese McKenna, David Gordon, Daniel James Kenny
  • Mass spectrometer
    Patent number: 8987661
    Abstract: A mass spectrometer is disclosed comprising a quadrupole rod set ion trap wherein a potential field is created at the exit of the ion trap which decreases with increasing radius in one radial direction. Ions within the on trap are mass selectively excited in a radial direction. Ions which have been excited in the radial direction experience a potential field which no longer confines the ions axially within the ion trap but which instead acts to extract the ions and hence causes the ions to be ejected axially from the ion trap.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: March 24, 2015
    Assignee: Micromass UK Limited
    Inventors: Martin Raymond Green, Daniel James Kenny, David J. Langridge, Jason Lee Wildgoose
  • Ion inlet for a mass spectrometer
    Patent number: 8987663
    Abstract: An ion inlet for a mass spectrometer is disclosed comprising a housing having a sampling orifice and an atmospheric pressure orifice. One or more gas outlets are provided in the housing. Gas is drawn through the sampling orifice by a pump so that the gas exits via the one or more gas outlets.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: March 24, 2015
    Assignee: Micromass UK Limited
    Inventors: David Gordon, Daniel James Kenny, Steven Derek Pringle
  • Performance Improvements for RF-Only Quadrupole Mass Filters and Linear Quadrupole Ion Traps With Axial Ejection
    Publication number: 20150060658
    Abstract: A RF only quadrupole rod set mass filter or mass analyser and a linear quadrupole ion trap with axial ejection are disclosed comprising a first pair of rod electrodes, a second pair of rod electrodes and an energy filter. The first pair of rod electrodes is longer than the second pair of rod electrodes. Ions having desired mass to charge ratios experience fringing fields at an exit region which results in the ions possessing sufficient axial kinetic energy to be transmitted by the energy filter. Other ions possess insufficient axial kinetic energy to be transmitted by the energy filter and are attenuated.
    Type: Application
    Filed: November 6, 2014
    Publication date: March 5, 2015
    Inventors: David J. Langridge, Daniel James Kenny
  • Ion Guide Construction Method
    Publication number: 20150060655
    Abstract: A method of constructing an ion guide is disclosed comprising providing an elongated spine member and a plurality of plates. Each plate comprises an aperture therethrough for receiving the spine member and at least one electrode for use in guiding ions. The apertures of the plates are arranged around the spine member and the plates are arranged along the spine member. The plates are then locked in position on the spine member such that the plates are fixed axially with respect to the spine member and so that the electrodes of the plates are arranged so as to form an array of electrodes for use in guiding ions.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 5, 2015
    Inventors: John Richard Garside, Martin Raymond Green, Daniel James Kenny, Jeffrey Ellis Lockett, Richard Barrington Moulds
  • Ion tunnel ion guide
    Patent number: 8957368
    Abstract: An ion guide is disclosed comprising a plurality of axial groupings of electrodes, wherein each axial grouping of electrodes comprises a ring or annular electrode which has been radially segmented into a plurality of electrode segments.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: February 17, 2015
    Assignee: Micromass UK Limited
    Inventor: Daniel James Kenny
  • MALDI Imaging and Ion Source
    Publication number: 20150034814
    Abstract: An ion source for a mass spectrometer is disclosed comprising a lens and mirror arrangement which focuses a laser beam onto the upper surface of a target substrate. The lens has an effective focal length ?300 mm. The laser beam is directed onto the target substrate at an angle ? with respect to the perpendicular to the target substrate, wherein ??3°. One or more ion guides receive ions released from the target substrate and onwardly transmit the ions along an ion path which substantially bypasses the lens and mirror.
    Type: Application
    Filed: July 6, 2012
    Publication date: February 5, 2015
    Applicant: MICROMASS UK LIMITED
    Inventors: Jeffery Mark Brown, Paul Murray, Daniel James Kenny
  • Ion trap with spatially extended ion trapping region
    Patent number: 8946626
    Abstract: A mass or mass to charge ratio selective ion trap is disclosed having an increased charge storage capacity. A RF voltage acts to confine ions in a first (y) direction within the ion trap. A DC voltage and/or an RF voltage acts to confine ions in a second (x) direction within the ion trap. A quadratic DC potential well acts to confine ions in a third (z) direction within the ion trap. Ions are excited in the third (z) direction and are caused to be mass or mass to charge ratio selectively ejected in the third (z) direction.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: February 3, 2015
    Assignee: Micromass UK Limited
    Inventors: Kevin Giles, Martin Raymond Green, Daniel James Kenny, David J. Langridge, Jason Lee Wildgoose
  • Method to detect and sequence post translationally modified peptides
    Patent number: 8916386
    Abstract: A method of detecting and sequencing post translationally modified peptides is disclosed wherein a negative ion precursor scan is performed. A negative ion high resolution MS scan is then performed and then MRM channels in positive ion mode are determined and monitored. A positive ion MS/MS scan is then performed.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: December 23, 2014
    Assignee: Micromass UK Limited
    Inventors: Christopher John Hughes, Therese McKenna, David Gordon, Daniel James Kenny
  • Performance improvements for RF-only quadrupole mass filters and linear quadrupole ion traps with axial ejection
    Patent number: 8901486
    Abstract: A RF only quadrupole rod set mass filter or mass analyzer and a linear quadrupole ion trap with axial ejection are disclosed comprising a first pair of rod electrodes, a second pair of rod electrodes and an energy filter. The first pair of rod electrodes is longer than the second pair of rod electrodes. Ions having desired mass to charge ratios experience fringing fields at an exit region which results in the ions possessing sufficient axial kinetic energy to be transmitted by the energy filter. Other ions possess insufficient axial kinetic energy to be transmitted by the energy filter and are attenuated.
    Type: Grant
    Filed: September 17, 2012
    Date of Patent: December 2, 2014
    Assignee: Micromass UK Limited
    Inventors: David J. Langridge, Daniel James Kenny