Patents by Inventor Daniel James Koch

Daniel James Koch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole derivatives for the treatment of depression and anxiety
    Patent number: 7144898
    Abstract: The present invention provides compounds of formula (I): which are useful for treating depression, anxiety, and alleviating the symptoms caused by withdrawal or partial withdrawal from the use of tobacco or of nicotine.
    Type: Grant
    Filed: December 6, 2000
    Date of Patent: December 5, 2006
    Assignee: Eli Lilly and Company
    Inventors: Marvin Martin Hansen, John Xiaoqiang He, Nicholas Allan Honigschmidt, Daniel James Koch, Todd Jonathan Kohn, Vincent Patrick Rocco, Patrick Gianpietro Spinazze, Kumiko Takeuchi
  • Indole derivatives for the treatment of depression and anxiety
    Publication number: 20040006229
    Abstract: The present invention provides compounds of formula (I): which are useful for treating depression, anxiety, and alleviating the symptoms caused by withdrawal or partial withdrawal from the use of tobacco or of nicotine.
    Type: Application
    Filed: September 30, 2002
    Publication date: January 8, 2004
    Inventors: Marvin Martin Hansen, John Xiaoqiang He, Nicholas Allan Honigschmidt, Daniel James Koch, Todd Jonathan Kohn, Vincent Patrick Rocco, Patrick Gianpietro Spinazze, Kumiko Takeuchi
  • 5-HT1F agonists
    Patent number: 6358972
    Abstract: The present invention relates to a compound of formula (I): or a pharmaceutical acid addition salt thereof; which is useful for activating 5-HT1f receptors and inhibiting protein extravasation in a mammal.
    Type: Grant
    Filed: December 5, 2000
    Date of Patent: March 19, 2002
    Assignee: Eli Lilly and Company
    Inventors: Sandra Ann Filla, Daniel James Koch, Brian Michael Mathes, Vincent Patrick Rocco
  • Inhibitors of serotonin reuptake
    Patent number: 6303627
    Abstract: This invention provides compounds and a method for the inhibition of serotonin reuptake in mammals.
    Type: Grant
    Filed: June 3, 1999
    Date of Patent: October 16, 2001
    Assignee: Eli Lilly and Company
    Inventors: Daniel James Koch, Vincent Patrick Rocco
  • 5-HT1F antagonists
    Patent number: 6242450
    Abstract: This invention provides 5-HT1f antagonists of Formula I: where AR1, AR2, R, and R′ are as defined in the specification.
    Type: Grant
    Filed: June 17, 1999
    Date of Patent: June 5, 2001
    Assignee: Eli Lilly and Company
    Inventors: Daniel James Koch, Lee Alan Phebus, Vincent Patrick Rocco, Tammy Joy Sajdyk
  • 5-substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)-and 3-(piperidin-4-yl)-1h-indoles: 5-HT.sub.1F agonists
    Patent number: 5962474
    Abstract: This invention provides novel 5-HT.sub.1F agonists of Formula I ##STR1## where A--B, R,R.sup.1 and X are as defined in the specification, which are useful for the treatment of migraine and associated disorders.
    Type: Grant
    Filed: November 24, 1997
    Date of Patent: October 5, 1999
    Assignee: Eli Lilly and Company
    Inventors: James Edmund Audia, Bruce Anthony Dressman, James Joseph Droste, James Erwin Fritz, Stephen Warren Kaldor, Daniel James Koch, Joseph Herman Krushinski, Jr., Jeffrey Scott Nissen, Vincent Patrick Rocco, John Mehnert Schaus, Dennis Charles Thompson
  • Compounds having effects on serotonin-related systems
    Patent number: 5912256
    Abstract: A series of 1-(4-indolyloxy)-3-(4-hydroxy-4-naphthylpiperidin-1-yl)propanes are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1.sub.A receptor, yet lack mutagenic potential as measured by assays of chromosomal aberration. The compounds are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal, and for the treatment of depression and other conditions for which serotonin reuptake inhibitors are used.
    Type: Grant
    Filed: May 22, 1997
    Date of Patent: June 15, 1999
    Assignee: Eli Lilly and Company
    Inventors: Daniel James Koch, Vincent Patrick Rocco
  • 5-Substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)-and 3-(piperidin-4-yl)-1H-indoles: new 5-HT.sub.1F agonists
    Patent number: 5708008
    Abstract: This invention provides novel 5-HT.sub.1F agonists of Formula I ##STR1## where A--B, R, R.sup.1 and X are as defined in the specification, which are useful for the treatment of migraine and associated disorders.
    Type: Grant
    Filed: March 20, 1996
    Date of Patent: January 13, 1998
    Assignee: Eli Lilly and Company
    Inventors: James Edmund Audia, Bruce Anthony Dressman, James Joseph Droste, James Erwin Fritz, Stephen Warren Kaldor, Daniel James Koch, Joseph Herman Krushinski, Jr., Jeffrey Scott Nissen, Vincent Patrick Rocco, John Mehnert Schaus, Dennis Charles Thompson