Patents by Inventor Daniel James Salamango

Daniel James Salamango has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Real-time reporter systems for monitoring base editing
    Patent number: 11332749
    Abstract: Real-time systems for monitoring base editing in living cells, including base editing by APOBEC-Cas9 fusions, is provided herein.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: May 17, 2022
    Assignee: Regents of the University of Minnesota
    Inventors: Reuben S. Harris, Daniel James Salamango, Amber Renee St. Martin
  • NON-COVALENT SYSTEMS AND METHODS FOR DNA EDITING
    Publication number: 20210108188
    Abstract: This document relates to materials and methods for DNA base editing with reduced off-target mutations. In particular, this document relates to materials and methods that include using fusion proteins containing a Cas9 molecule and an APOBEC-interacting molecule to achieve specific DNA edits with reduced levels of off-target edits.
    Type: Application
    Filed: October 9, 2020
    Publication date: April 15, 2021
    Inventors: Reuben S. Harris, Jennifer McCann, Daniel James Salamango
  • APOBEC ENZYMES WITH INCREASED DNA EDITING ACTIVITY, AND METHODS FOR THEIR USE
    Publication number: 20200131496
    Abstract: Materials and methods for using modified APOBEC polypeptides for modification of DNA sequences are provided herein.
    Type: Application
    Filed: October 25, 2019
    Publication date: April 30, 2020
    Inventors: Reuben S. Harris, Amber Renee St. Martin, Nadine Shaban, Daniel James Salamango