Abstract: According to one or more embodiments of the disclosure, an asset inventory service executed by one or more devices receives telemetry data collected passively by a sensor application regarding a node in a network. The asset inventory service requests, after receiving the telemetry data, that the sensor application perform active discovery of nodes in the network. The asset inventory service receives active discovery data collected by the sensor application via active discovery of nodes in the network. The asset inventory service generates, based on the telemetry data and the active discovery data, an identity profile for the node.

Abstract: A device includes including an elongated hollow member with a window for receiving tissue in an interior of the hollow member; a rigid member slidably coupled to the hollow member; and an actuation mechanism configured to move the rigid member longitudinally along a longitudinal axis through at least part of the window. When a ligation band is adjacent to the window and the rigid member is moved relative to the hollow member, the rigid member deforms the ligation band from an open position into a closed position around tissue received in the window.

Abstract: The present application relates to arenaviruses with rearrangements of their open reading frames (“ORF”) in their genomes. In particular, described herein is a modified arenavirus genomic segment, wherein the arenavirus genomic segment is engineered to carry a viral ORF in a position other than the wild-type position of the ORF. Also described herein are trisegmented arenavirus particles comprising one L segment and two S segments or two L segments and one S segment. The arenavirus, described herein may be suitable for vaccines and/or treatment of diseases and/or for the use in immunotherapies.

Abstract: Compounds are provided according to Formula (A): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R1A, R1B, n, R2A, R2B, R3, and R4 are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.

Abstract: A mesh for an atomizer assembly is provided, including a first surface, a second surface, and a plurality of nozzles extending between the first surface and the second surface, the first surface being at least partially coated with a hydrophilic coating or the second surface being at least partially coated with a hydrophobic coating, the plurality of nozzles defining an inner surface, and the inner surface being at least partially coated with the hydrophilic coating. An atomizer assembly for an aerosol-generating device, and an aerosol-generating device comprising an atomizer assembly, are also provided.

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: An aerosol-generating article is provided for producing an inhalable aerosol when heated, the aerosol-generating article including: a hollow cylindrical rod of aerosol-generating substrate; a wrapper circumscribing the hollow cylindrical rod; and a hollow tube extending along a longitudinal axis of the hollow cylindrical rod and defining a central airflow channel of the aerosol-generating article, the hollow tube including a plurality of openings extending through a wall of the hollow tube, such that the aerosol-generating substrate in the hollow cylindrical rod is in fluid communication with the central airflow channel through the plurality of openings, and such that a ratio between a cumulative cross-sectional area of the plurality of openings and a cross-sectional area of the central airflow channel is from about 0.042 to about 0.672.

Abstract: Techniques for configuring test operations on a per-module basis are disclosed. A system receives a command for configuring, on a per-module basis, test operations recited in a set of module code corresponding to a particular module of a plurality of modules in a module system. The module system specifies accessibility of each module in the plurality of modules to other modules in the plurality of modules. The system stores configuration information based on the command and configures a test operation included in an element of the particular module based on the stored configuration information. Configuring the test operation includes one of: (a) enabling the test operation without affecting other code recited in-line with the test operation in the element of the particular module; or (b) disabling the test operation without affecting other code recited in-line with the test operation in the element of the particular module.

Abstract: A lattice formed of entwined links in a cavity encased by the external skin of a blade and provided with parts of low mechanical strength referred to as breakable, which are capable of rupturing when sufficient loads are applied thereto during operation of the blade. This arrangement, which concentrates the ruptures at given locations, will leave the rest of the lattice intact and therefore will not hamper or will scarcely hamper its properties of heat evacuation by conduction or convection or pressure loss, if for example ventilation air passes through it.

Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhoea and C. difficile associated colitis.

Abstract: The present disclosure relates to hollow fiber tangential flow filter units, including hollow fiber tangential flow depth filter units, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.

Abstract: The present disclosure relates to spectroscopy with light emitting components including, e.g., UV and/or visible wavelength light, for various applications, including, e.g., chromatography, and more particularly, for a sampling device that facilitates spectroscopic measurements with a variable pathlength and methods for such a device. In an aspect, a device for measuring light absorbance of a sample may include a fluid conduit comprising a first portion, a midportion substantially perpendicular to the first portion, and a second portion substantially perpendicular to the midportion. A first probe may be within the midportion and substantially parallel with the midportion. The first probe may comprise a distal end. A light source may be operably coupled to the first probe. A detector may be aligned with the distal end of the first probe substantially perpendicular to the first probe at a pathlength from the distal end of the first probe.

Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Grain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.

Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Grain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.

Abstract: A lattice formed of entwined links in a cavity encased by the external skin of a blade and provided with parts of low mechanical strength referred to as breakable, which are capable of rupturing when sufficient loads are applied thereto during operation of the blade. This arrangement, which concentrates the ruptures at given locations, will leave the rest of the lattice intact and therefore will not hamper or will scarcely hamper its properties of heat evacuation by conduction or convection or pressure loss, if for example ventilation air passes through it.

Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenesGrain positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.

Abstract: A turbine of a turbomachine includes a ceramic matrix composite sector of a stator includes an outer platform and an inner platform connected via at least one vane. The outer platform has means for attaching to a sector of a metallic support, the attachment means having at least one central rim and two lateral rims. The central rim is radially offset with respect to said lateral rims along a directrix line such that the central rim is radially on one side of said directrix line and the lateral rims on the other. The central rim and said central hook bear radially against one another and are located radially on either side of said directrix line. The lateral rim and said corresponding lateral hook bear radially against one another and are located radially on either side of said directrix line.

Abstract: A passive heat exchanger includes an evaporator section including a heat exchange surface formed complementary to a surface of a gas turbine engine component to be cooled. The heat exchange surface is configured to be thermally coupled in conductive contact to the component surface. The heat exchanger further includes a condenser section coupled in passive convective flow communication with the evaporator section, and a working fluid contained within the evaporator section and the condenser section and configured to passively convect heat from the evaporator section to the condenser section.

Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhoea and C. difficile associated colitis.

Abstract: Techniques are included for providing a parallel pseudo infinite timeline monotonic clock that may be used to determine time and durations. A system clock is used to obtain an original time instant that anchors the pseudo infinite timeline to be parallel to a timeline of the system clock. The monotonic clock obtains time ticks from a monotonic tick supplier. The monotonic time ticks are used to determine times and durations, rather than relying on time instants obtained from the system clock. The use of a sliding window anchored at various times allows the parallel timeline to be almost infinite in implementation, rather than wrapping once a maximum value is reached. In addition, the accuracy of computations of time and duration are impervious to changes to the system clock, due to the use of the monotonic time ticks instead of obtaining multiple time instants from the system clock.