Abstract: Method and system for diagnosing and treating thalamocortical dysrhythmia. Thalamocortical dysrhythmia occurs when unbalanced neural activity occurs due to the rise of low frequency (approximately 4-8 Hz) and high frequency (approximately 20-50 Hz) neuronal oscillation activity simultaneously within awake individuals. The underlying mechanism that causes thalamocortical dysrhythmia is abnormal input into thalamic cells, which causes a low-frequency shift, increased amplitude, and increased frequency correlation of neuronal oscillation at the cortical and thalamic levels. The present invention measures the neuronal activity at the cortical level, filters these measurements, and performs a Fourier transform to transfer neuronal oscillation data into the frequency domain. The present invention then selects at least one reference baseline based on the characteristics of control subjects that do not have thalamocortical dysrhythmia and/or patients that have thalamocortical dysrhythmia.

Abstract: Method and system for diagnosing and treating thalamocortical dysrhythmia. Thalamocortical dysrhythmia occurs when unbalanced neural activity occurs due to the rise of low frequency (approximately 4-8 Hz) and high frequency (approximately 20-50 Hz) neuronal oscillation activity simultaneously within awake individuals. The underlying mechanism that causes thalamocortical dysrhythmia is abnormal input into thalamic cells, which causes a low-frequency shift, increased amplitude, and increased frequency correlation of neuronal oscillation at the cortical and thalamic levels. The present invention measures the neuronal activity at the cortical level, filters these measurements, and performs a Fourier transform to transfer neuronal oscillation data into the frequency domain. The present invention then selects at least one reference baseline based on the characteristics of control subjects that do not have thalamocortical dysrhythmia and/or patients that have thalamocortical dysrhythmia.