Patents by Inventor Daniel Jed Harrison

Daniel Jed Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Optogenetic probes for measuring membrane potential
    Patent number: 10800829
    Abstract: Provided herein are variants of an archaerhodopsin useful for application such as optical measurement of membrane potential. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, cells comprising the polynucleotides, and cells comprising the polypeptides; and methods of using the variants.
    Type: Grant
    Filed: October 16, 2019
    Date of Patent: October 13, 2020
    Assignees: President and Fellows of Harvard College, The Governors of the University of Alberta
    Inventors: Adam Ezra Cohen, Daniel Hochbaum, Peng Zou, Samouil Leon Farhi, Robert Earl Campbell, Yongxin Zhao, Daniel Jed Harrison
  • OPTOGENETIC PROBES FOR MEASURING MEMBRANE POTENTIAL
    Publication number: 20200123218
    Abstract: Provided herein are variants of an archaerhodopsin useful for application such as optical measurement of membrane potential. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, cells comprising the polynucleotides, and cells comprising the polypeptides; and methods of using the variants.
    Type: Application
    Filed: October 16, 2019
    Publication date: April 23, 2020
    Applicants: President and Fellows of Harvard College, The Governors of the University of Alberta
    Inventors: Adam Ezra Cohen, Daniel Hochbaum, Peng Zou, Samouil Leon Farhi, Robert Earl Campbell, Yongxin Zhao, Daniel Jed Harrison
  • Optogenetic probes for measuring membrane potential
    Patent number: 10457715
    Abstract: Provided herein are variants of an archaerhodopsin useful for application such as optical measurement of membrane potential. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, cells comprising the polynucleotides, and cells comprising the polypeptides; and methods of using the variants.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: October 29, 2019
    Assignees: President and Fellows of Harvard College, The Governors of the University of Alberta
    Inventors: Adam E. Cohen, Daniel Hochbaum, Peng Zou, Samouil Leon Farhi, Robert Earl Campbell, Yongxin Zhao, Daniel Jed Harrison
  • OPTOGENETIC PROBES FOR MEASURING MEMBRANE POTENTIAL
    Publication number: 20170313757
    Abstract: Provided herein are variants of an archaerhodopsin useful for application such as optical measurement of membrane potential. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, cells comprising the polynucleotides, and cells comprising the polypeptides; and methods of using the variants.
    Type: Application
    Filed: November 28, 2016
    Publication date: November 2, 2017
    Applicants: President and Fellows of Harvard College, The Governors of the University of Alberta
    Inventors: Adam E. Cohen, Daniel Hochbaum, Peng Zou, Samouil Leon Farhi, Robert Earl Campbell, Yongxin Zhao, Daniel Jed Harrison
  • Optogenetic probes for measuring membrane potential
    Patent number: 9518103
    Abstract: Provided herein are variants of an archaerhodopsin useful for application such as optical measurement of membrane potential. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, cells comprising the polynucleotides, and cells comprising the polypeptides; and methods of using the variants.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: December 13, 2016
    Assignees: President and Fellows of Harvard College, The Governors of the University of Alberta
    Inventors: Adam E. Cohen, Daniel Hochbaum, Peng Zou, Samouil Leon Farhi, Robert Earl Campbell, Yongxin Zhao, Daniel Jed Harrison
  • OPTOGENETIC PROBES FOR MEASURING MEMBRANE POTENTIAL
    Publication number: 20150369740
    Abstract: Provided herein are variants of an archaerhodopsin useful for application such as optical measurement of membrane potential. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, cells comprising the polynucleotides, and cells comprising the polypeptides; and methods of using the variants.
    Type: Application
    Filed: June 17, 2015
    Publication date: December 24, 2015
    Applicants: President and Fellows of Harvard College, The Governors of the University of Alberta
    Inventors: Adam E. Cohen, Daniel Hochbaum, Peng Zou, Samouil Leon Farhi, Robert Earl Campbell, Yongxin Zhao, Daniel Jed Harrison
  • Microfluidic system and methods of use
    Patent number: 6900021
    Abstract: This invention relates to a novel microfluidic device and methods of using this device to conduct in vitro studies on the reaction and effects of various compounds on cells. More particularly, it relates to a method for using stop flow in a microfluidic system to study the effect of compounds on individual cells. It also provides a method for observing the effects of candidate compounds on leukocyte rolling.
    Type: Grant
    Filed: May 18, 1998
    Date of Patent: May 31, 2005
    Assignee: The University of Alberta
    Inventors: Daniel Jed Harrison, Per Andersson, Paul C. H. Li, Roderick Szarka, Richard Smith, Hossein Salimi-Moosavi
  • Microfluidic system and methods of use
    Publication number: 20040178071
    Abstract: This invention relates to a novel microfluidic device and methods of using this device to conduct in vitro studies on the reaction and effects of various compounds on cells. More particularly, it relates to a method for using stop flow in a microfluidic system to study the effect of compounds on individual cells.
    Type: Application
    Filed: August 11, 2003
    Publication date: September 16, 2004
    Applicants: The Governors of the University of Alberta, Alberta Research Council
    Inventors: Daniel Jed Harrison, Paul C.H. Li, Roderick Szarka, Richard Smith, Per Anderson
  • Microfluidic system and methods of use
    Patent number: 6632619
    Abstract: This invention relates to a novel microfluidic device and methods of using this device to conduct in vitro studies on the reaction and effects of various compounds on cells. More particularly, it relates to a method for using stop flow in a microfluidic system to study the effect of compounds on individual cells.
    Type: Grant
    Filed: May 16, 1997
    Date of Patent: October 14, 2003
    Assignee: The Governors of the University of Alberta
    Inventors: Daniel Jed Harrison, Per Andersson, Paul C. H. Li, Roderick Szarka, Richard Smith