Patents by Inventor Daniel John Finnemore

Daniel John Finnemore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OXADIAZOLYLTHIOPHENE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS
    Publication number: 20210038607
    Abstract: A compound of Formula I: (I) or a pharmaceutically acceptable salt thereof, wherein: each R? is QR1; each Q is independently selected from a bond, —C1-C10 alkylene, —C2-C10 alkenylene, —C(O)—, —C(O)O—, —C(O)N(R1)—, —C(O)N(R1)SO2—N(R1)C(O)—, —N(R1)—, —N(SO2(R1)), —N(R1)SO2—C(O)NR4R5—, —N(R4R5)C(O)—, —N(R4R5)—S—, —SO—, —SO2—, —S(O)O—, —SO2N(R1)— and —O—; each R1 is independently selected from H, C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, C1-C10 haloalkyl, C1-C10 heteroalkyl, aryl, heteroaryl, C3-C10 cycloalkyl, —(C1-C10 alkylene)-C3-C10 cycloalkyl, halogen, cyano, C1-C10 alkylene-aryl, C1-C10 alkylene heteroaryl, C1-C10 heterocycloalkyl and —(C1-C10 alkylene)-C1-C10 heterocycloalkyl. The compounds are inhibitors of HDAC and therefore have potential utility in the therapy of a number of conditions including cancer and inflammation.
    Type: Application
    Filed: March 1, 2019
    Publication date: February 11, 2021
    Inventors: Stephen Joseph Shuttleworth, Alice Elizabeth Gatland, Daniel John Finnemore, Rikki Peter Alexander, Franck Alexandre Silva, Alexander Richard Liam Cecil
  • Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors
    Patent number: 10377764
    Abstract: The invention relates to a compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein each R3 is independently selected from H, halo, fluorinated C1-C10 alkyl, —I—C1-C10 alkyl, —NH—C1-C10 alkyl, —S—C1-C10 alkyl, —O-fluorinated C1-C10 alkyl, —NH-acyl, —NH—C(O)—NH-alkyl, —C—(O)—NH-alkyl, with the proviso that at least one of R3 is not H.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: August 13, 2019
    Assignee: Karus Therapeutics Limited
    Inventors: Stephen Joseph Shuttleworth, Franck Alexandre Silva, Alexander Richard Liam Cecil, Alice Elizabeth Gatland, Daniel John Finnemore
  • TRICYCLIC HETEROCYCLIC COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE INHIBITORS
    Publication number: 20180244686
    Abstract: The invention relates to a compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein each R3 is independently selected from H, halo, fluorinated C1-C10 alkyl, —I—C1-C10 alkyl, —NH—C1-C10 alkyl, —S—C1-C10 alkyl, —O-fluorinated C1-C10 alkyl, —NH-acyl, —NH—C(O)—NH-alkyl, —C—(O)—NH-alkyl, with the proviso that at least one of R3 is not H.
    Type: Application
    Filed: August 19, 2016
    Publication date: August 30, 2018
    Inventors: Stephen Joseph Shuttleworth, Franck Alexandre Silva, Alexander Richard Liam Cecil, Alice Elizabeth Gatland, Daniel John Finnemore