Abstract: A radiation shielding structure or vault includes an outer wall and an inner wall. The outer wall includes at least one outer wall panel formed into a cylinder shape having an outer wall opening. The inner wall includes at least one inner wall panel formed into a cylinder shape having an inner wall opening aligned with the outer wall opening. Tie rods secure the inner wall to the outer wall to support and hold the spacing between the walls. A tunnel structure is inside the inner wall opening and the outer wall opening. A radiation shielding door is coupled to the tunnel structure. A radiation shielding filler material is disposed in between the outer wall and the inner wall.

Abstract: A compound of Formula I: (I) or a pharmaceutically acceptable salt thereof, wherein: each R? is QR1; each Q is independently selected from a bond, —C1-C10 alkylene, —C2-C10 alkenylene, —C(O)—, —C(O)O—, —C(O)N(R1)—, —C(O)N(R1)SO2—N(R1)C(O)—, —N(R1)—, —N(SO2(R1)), —N(R1)SO2—C(O)NR4R5—, —N(R4R5)C(O)—, —N(R4R5)—S—, —SO—, —SO2—, —S(O)O—, —SO2N(R1)— and —O—; each R1 is independently selected from H, C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, C1-C10 haloalkyl, C1-C10 heteroalkyl, aryl, heteroaryl, C3-C10 cycloalkyl, —(C1-C10 alkylene)-C3-C10 cycloalkyl, halogen, cyano, C1-C10 alkylene-aryl, C1-C10 alkylene heteroaryl, C1-C10 heterocycloalkyl and —(C1-C10 alkylene)-C1-C10 heterocycloalkyl. The compounds are inhibitors of HDAC and therefore have potential utility in the therapy of a number of conditions including cancer and inflammation.

Abstract: Systems and apparatuses for administering reduced pressure treatment to a tissue site include a reduced pressure source, a drape having a plurality of projections for contacting the tissue site, and an adhesive connected to at least a portion of the drape for sealing the drape to a portion of a patient's intact epidermis.

Abstract: A respiratory assistance system including a humidification apparatus used for delivery of heated and humidified gases to a patient includes a humidification chamber with an associated heater and sensor, an inspiratory conduit with an associated heater and sensor, and an unheated patient interface, such as a face mask. A controller of the humidification apparatus is configured to determine a gas source and change the set point accordingly to maintain patient comfort regardless of the humidity level of the gas source.

Abstract: A FOOD SLOTTING DEVICE includes a holding unit, an assembly of slicing blades arranged in a perpendicular fashion, and an affixed cover piece, for creating an elongated cross-hatch pattern of perpendicular slots by partially slicing into one or more surface areas on the body of a food product, generally of an elongated nature, such as a hot dog, wiener, frankfurter, sausage or the like through the directional application of force, such as the METHOD of carrying out such partial slicing denotes. Thereafter the partially sliced food product is easily removed from the slicing blades assembly of the FOOD SLOTTING DEVICE prior to cooking, grilling, or further processing. The slots prevent bursting by permitting gases generated by the cooking process to escape, allowing penetration of the heat to the center of the food product providing quicker cooking thereof, thereby providing for a more palatable and pleasant looking food product.

Abstract: A customizable mask including a conforming seal is configured to utilize the physical process of granular jamming to enable it to adapt to a wide range of facial geometries. The mask may include a frame having a perimeter and a conduit connection, a conforming seal positioned along the perimeter of the frame. The conforming seal may include a sealing surface and a connecting surface, the connecting surface configured to mate with the perimeter of the frame, and the sealing surface configured to conform to a users' face. The conforming seal may further include an outer casing, granular material contained within the outer casing, and a vacuum connection. The mask may also include a similarly configured conforming frame. Further disclosed are methods of forming such masks.

Abstract: The invention relates to a new method of determining in a sample the presence or absence of one or more analyte members of a group of two or more analytes. The invention therefore relates to a multiplex assay for determining the presence or absence of each analyte in a group of multiple analytes. The assay uses aptamers and transmembrane pores.

Abstract: A thin ribbon spirally wound polymer conduit and method of forming, wherein a helical reinforcing bead is interposed adjacent overlapping layers of ribbon. Further, a method of continuously forming spirally wound conduit wherein a sacrificial layer, preferably having a different base polymer to that of the conduit, is first applied to the former before the conduit is formed overtop.

Abstract: Systems and methods are described for managing services of a computing device over a mobile network where requests for managed or unmanaged services are translated to corresponding IP addresses sent to the computing device and corresponding requests sent to the translated IP addresses are either permitted, rated, quality controlled or secured if the computing device has a valid data plan or is otherwise permissioned for using the mobile network, are denied if filtered and if the computing device does not have a valid data plan or is not otherwise permissioned and the request corresponds to the first address, and are permitted, rated, quality controlled or not secured even if the computing device does not have a valid data plan or is not otherwise permissioned if the request corresponds to the second address.

Abstract: A slips positioning apparatus for a wellhead installation is installed in a fixed position relative to the blow out preventer and allows releasable locking of the slips relative to well center and driving movement of the slips relative to well center. The slips positioning apparatus includes a slips-mounting structure for accepting connection of the slips; an installation structure for mounting the apparatus rigidly above the blow out preventer and relative to well center. The installation structure is a plate that defines a first plane. The apparatus further includes a first and a second linear guides configured for movement of the slips-mounting structure relative to the installation structure along respective first and second directions in planes substantially parallel with the first plane; and first and second linear actuators for moving the slips-mounting structure respectively along the first and second linear guides.

Abstract: An SMA actuator (10) comprising SMA wires (31, 32) in which the wire arrangement is asymmetrical, allowing a greater range of motion from a rest position in a first direction than in a second direction, which may be opposite or orthogonal to the first direction. Where the directions are opposite, the angle between a principal axis and the wires providing motion in the first direction may be different from the angle between the principal axis and the wires providing motion in the second direction.

Abstract: Embodiments of systems, methods, and devices for protecting service personnel by deploying a physical barrier are described. Further embodiments describe additional security features such as lights, sirens, cameras, electronic locks, timers, and/or notifying security personnel or local law enforcement when the system is activated.

Abstract: A cable puller includes a frame, a capstan mounted on the frame around which a pulling rope is wrapped, and a sensor configured to measure the distance the pulling rope travels relative to the frame. The sensor may be a Hall effect sensor and/or an optical sensor.

Abstract: The present disclosure relates to TGF-beta antibodies and binding fragments thereof, DNA encoding the same, host cells comprising said DNA and methods of expressing the antibody or binding fragment in a host cell. The disclosure also extends to pharmaceutical compositions comprising the antibody or a binding fragment thereof and use of the antibody, binding fragment and compositions comprising the same in treatment of various diseases including fibrosis.

Abstract: Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is associated with a neurovascular bundle, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating inflammatory disorders. The invention provides improved ways of treating inflammatory disorders which minimize off-target effects.

Abstract: THIS invention relates to an integrated process for recovering the valuable iron fraction from low grade iron ore, including the steps of: comminution 14 and classification 36/39 to obtain a classified fraction suitable for coarse flotation and classified fraction suitable for fine beneficiation; subjecting the fraction suitable for coarse flotation to coarse flotation 40 to obtain an intermediate iron concentrate 42 and a coarse sand residue 44; grinding the intermediate concentrate to a size suitable for fine beneficiation; and subjecting the fractions suitable for fine beneficiation to fine beneficiation 46 and obtaining a final iron concentrate 48 and a fine tailings 50.

Abstract: A system and method for managing power consumption of HVAC system includes a transfer switch, a detector interface and an HVAC controller of the HVAC system. The transfer switch is configured to switch a power line supplied to a load between a utility power source and a backup power source. The detector interface is in communication with the transfer switch or a controller of the backup power source and the HVAC controller. The HVAC controller is configured to receive data regarding the switching of power line supplied to the load between the utility power source and the backup power source and control an operation of components of the HVAC system based on the capacity of power source, thereby manages or lowers the power consumption of HVAC system. The detector interface is configured to provide switching information and capacity of the backup power source to the HVAC controller.

Abstract: A fastener for securing a first object to a second object includes a push member, a rigid shaft, an engaging member, a biasing member, and an anchor. The push member and the anchor are fixed to opposite ends of the rigid shaft. The engaging member is slideably coupled to the rigid shaft between the push member and the anchor. The biasing member is disposed between the push member and the engaging member to urge the engaging member toward the anchor. In a particular embodiment, the anchor is deployable.

Abstract: A weed barrier includes a rigid body defining a plurality of basins. The basins have bottoms with holes therethrough for planting garden plants. In a particular embodiment the bottom surface of the weed barrier includes a plurality of hose channels configured be positioned over a hose. Several example configurations of rigid weed barriers are disclosed.

Abstract: The illustrative embodiments described herein are directed to an apparatus, system, and method for storing liquid from a tissue site. The apparatus may include a drape having an aperture, and a fluid pouch coupled to the drape such that the fluid pouch is in fluid communication with the aperture. In one embodiment, the fluid pouch is operable to transfer reduced pressure to the aperture such that the liquid from the tissue site is drawn into the fluid pouch. The fluid pouch may have a cavity that stores the liquid that is drawn from the tissue site. In another embodiment, the fluid pouch may include at least one baffle. The fluid pouch may also include a fluid channel at least partially defined by the at least one baffle. The fluid channel may be operable to store liquid from the tissue site when reduced pressure is applied through the fluid channel.