Patents by Inventor Daniel Joseph Christiaan Thone

Daniel Joseph Christiaan Thone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrobromide salt of an anti-HIV compound
    Patent number: 11253479
    Abstract: Solid dispersions and dosage forms comprising the hydrobromide salt of a diarylpyrimidine derivative, useful as an anti-HIV agent.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: February 22, 2022
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventor: Daniel Joseph Christiaan Thoné
  • Pseudopolymorphic Forms of a HIV Protease Inhibitor
    Publication number: 20210179631
    Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
    Type: Application
    Filed: October 30, 2020
    Publication date: June 17, 2021
    Inventors: Hans Wim Pieter Vermeersch, Daniel Joseph Christiaan Thone, Luc Donne Marie-Louise Janssens, Piet Tom Bert Paul Wigerinck
  • Pseudopolymorphic forms of a HIV protease inhibitor
    Patent number: 10858369
    Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl] isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: December 8, 2020
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Hans Wim Pieter Vermeersch, Daniel Joseph Christiaan Thone, Luc Donne Marie-Louise Janssens, Piet Tom Bert Paul Wigerinck
  • Pseudopolymorphic Forms of a HIV Protease Inhibitor
    Publication number: 20180312517
    Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl] isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
    Type: Application
    Filed: May 16, 2018
    Publication date: November 1, 2018
    Inventors: Hans Wim Pieter Vermeersch, Daniel Joseph Christiaan Thone, Luc Donne Marie-Louise Janssens, Piet Tom Bert Paul Wigerinck
  • Pseudopolymorphic forms of a HIV protease inhibitor
    Patent number: 10000504
    Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
    Type: Grant
    Filed: May 22, 2017
    Date of Patent: June 19, 2018
    Assignee: Janssen Sciences Ireland UC
    Inventors: Hans Wim Pieter Vermeersch, Daniel Joseph Christiaan Thone, Luc Donne Marie-Louise Janssens, Piet Tom Bert Paul Wigerinck
  • HYDROBROMIDE SALT OF AN ANTI-HIV COMPOUND
    Publication number: 20180049986
    Abstract: Solid dispersions and dosage forms comprising the hydrobromide salt of a diarylpyrimidine derivative, useful as an anti-HIV agent.
    Type: Application
    Filed: October 27, 2017
    Publication date: February 22, 2018
    Inventor: Daniel Joseph Christiaan Thoné
  • Pseudopolymorphic Forms of a HIV Protease Inhibitor
    Publication number: 20170260196
    Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
    Type: Application
    Filed: May 22, 2017
    Publication date: September 14, 2017
    Inventors: Hans Wim Pieter Vermeersch, Daniel Joseph Christiaan Thone, Luc Donne Marie-Louise Janssens, Piet Tom Bert Paul Wigerinck
  • Pseudopolymorphic Forms Of A HIV Protease Inhibitor
    Publication number: 20150336980
    Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
    Type: Application
    Filed: August 4, 2015
    Publication date: November 26, 2015
    Inventors: Hans Wim Pieter VERMEERSCH, Daniel Joseph Christiaan THONE, Luc Donne Marie-Louise JANSSENS, Piet Tom Bert Paul WIGERINCK
  • Pseudopolymorphic Forms Of A HIV Protease Inhibitor
    Publication number: 20140171499
    Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
    Type: Application
    Filed: February 19, 2014
    Publication date: June 19, 2014
    Applicant: Janssen R&D Ireland
    Inventors: Hans Wim Pieter VERMEERSCH, Daniel Joseph Christiaan THONE, Luc Donne Marie-Louise JANSSENS, Piet Tom Bert Paul WIGERINCK
  • Process for preparing particles containing an antiviral
    Patent number: 8722696
    Abstract: A process for preparing a particle comprising a co-precipitate surrounding a neutral hydrophilic carrier, said process comprising spraying an organic solution on a neutral hydrophilic carrier, said solution comprising at least one triazine or pyrimidine active ingredient having HIV inhibiting properties, one surface active agent, and one hydrophilic polymer, wherein the spraying of whole of the solution occurs in at least two separate steps, each of these steps followed by a grinding step of the product obtained at the end of the preceding step.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: May 13, 2014
    Assignee: Janssen R&D Ireland
    Inventors: Gaël Lamoureux, Gérard Cousin, Daniel Joseph Christiaan Thoné
  • Pseudopolymorphic Forms Of A HIV Protease Inhibitor
    Publication number: 20130303790
    Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
    Type: Application
    Filed: July 11, 2013
    Publication date: November 14, 2013
    Inventors: Hans Wim Pieter VERMEERSCH, Daniel Joseph Christiaan Thone, Luc Donne Marie-Louise Janssens, Piet Tom Bert Paul Wigerinck
  • Pseudopolymorphic forms of a HIV protease inhibitor
    Patent number: 8518987
    Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl (1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: August 27, 2013
    Assignee: Janssen R&D Ireland
    Inventors: Hans Wim Pieter Vermeersch, Daniel Joseph Christiaan Thone, Luc Donne Marie-Louise Janssens, Piet Tom Bert Paul Wigerinck
  • PSEUDOPOLYMORPHIC FORMS OF A HIV PROTEASE INHIBITOR
    Publication number: 20100204316
    Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl (1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
    Type: Application
    Filed: August 6, 2009
    Publication date: August 12, 2010
    Inventors: Hans Wim Pieter VERMEERSCH, Daniel Joseph Christiaan Thone, Luc Donné Marie-Louise Janssens
  • Pseudopolymorphic forms of a HIV protease inhibitor
    Patent number: 7700645
    Abstract: New pseudopolymorphic forms of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate and processes for producing them are disclosed.
    Type: Grant
    Filed: May 16, 2003
    Date of Patent: April 20, 2010
    Assignee: Tibotec Pharmaceuticals Ltd.
    Inventors: Hans Wim Pieter Vermeersch, Daniel Joseph Christiaan Thoné, Luc Donné Marie-Louise Janssens
  • PROCESS FOR PREPARING PARTICLES CONTAINING AN ANTIVIRAL
    Publication number: 20100062069
    Abstract: A process for preparing a particle comprising a co-precipitate surrounding a neutral hydrophilic carrier, said process comprising spraying an organic solution on a neutral hydrophilic carrier, said solution comprising at least one triazine or pyrimidine active ingredient having HIV inhibiting properties, one surface active agent, and one hydrophilic polymer, wherein the spraying of whole of the solution occurs in at least two separate steps, each of these steps followed by a grinding step of the product obtained at the end of the preceding step.
    Type: Application
    Filed: September 3, 2009
    Publication date: March 11, 2010
    Inventors: Gaël LAMOUREUX, Gérard Cousin, Daniel Joseph Christiaan Thoné
  • HYDROBROMIDE SALT OF AN ANTI-HIV COMPOUND
    Publication number: 20100041687
    Abstract: Solid dispersions and dosage forms comprising the hydrobromide salt of a diarylpyrimidine derivative, useful as an anti-HIV agent.
    Type: Application
    Filed: December 6, 2007
    Publication date: February 18, 2010
    Inventor: Daniel Joseph Christiaan Thoné