Patents by Inventor Daniel Justin GERHARDT

Daniel Justin GERHARDT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bispecific GD2 and B7H3 Binding Molecules and Methods of Use
    Publication number: 20230018670
    Abstract: Disclosed herein are multi-specific antibody constructs that simultaneously bind two tumor cell surface antigens, GD2 and B7H3. The monovalent arms targeting GD2 and B7H3 are each low to moderate affinity for their respective antigens. The multi-specific antibodies disclosed herein bind to target tumor cells when both arms of the antibody bind to their antigens, resulting in high specificity of the antibody for GD2 and B7H3 expressing tumor cells.
    Type: Application
    Filed: February 20, 2021
    Publication date: January 19, 2023
    Inventors: Paul SONDEL, Daniel Justin GERHARDT
  • MULTISPECIFIC TREG BINDING MOLECULES
    Publication number: 20220213225
    Abstract: Multispecific Treg-binding molecules, constructs, pharmaceutical compositions comprising the constructs, and methods of use thereof are presented.
    Type: Application
    Filed: July 29, 2019
    Publication date: July 7, 2022
    Inventors: Lucas BAILEY, Bryan GLASER, Qufei LI, Roland GREEN, Dileep Kumar PULUKKUNAT, Bonnie HAMMER, Daniel Justin GERHARDT
  • MULTISPECIFIC TREG BINDING MOLECULES
    Publication number: 20220153844
    Abstract: Multispecific Treg-binding molecules, constructs, pharmaceutical compositions comprising the constructs, and methods of use thereof are presented.
    Type: Application
    Filed: January 13, 2021
    Publication date: May 19, 2022
    Inventors: Mandar BAWADEKAR, Lucas BAILEY, Bryan GLASER, Qufei LI, Roland GREEN, Dileep Kumar PULUKKUNAT, Bonnie HAMMER, Daniel Justin GERHARDT, Alexander RAKHMILEVICH, Paul SONDEL
  • TRIVALENT TRISPECIFIC ANTIBODY CONSTRUCTS
    Publication number: 20210179734
    Abstract: Trispecific trivalent antibody constructs, pharmaceutical compositions comprising the constructs, and methods of use thereof are presented.
    Type: Application
    Filed: April 17, 2019
    Publication date: June 17, 2021
    Inventors: Lucas BAILEY, Bryan GLASER, Qufei LI, Roland GREEN, Dileep Kumar PULUKKUNAT, Malgorzata Agnieszka NOCULA-LUGOWSKA, Daniel Justin GERHARDT
  • BINDING MOLECULES
    Publication number: 20210163594
    Abstract: Binding molecules, constructs, pharmaceutical compositions comprising the constructs, and methods of use thereof are presented.
    Type: Application
    Filed: April 17, 2019
    Publication date: June 3, 2021
    Inventors: Lucas BAILEY, Bryan GLASER, Qufei LI, Roland GREEN, Dileep Kumar PULUKKUNAT, Malgorzata Agnieszka NOCULA-LUGOWSKA, Daniel Justin GERHARDT, Matthew Joseph BISSEN