Abstract: An automated method for analyzing the photometric calibration and image quality performance characteristics of a high resolution storage phosphor reader. A custom fabricated, lead mask test target is secured to a storage phosphor and exposed using a standard medical x-ray source. A storage phosphor reader, to be calibrated, reads the exposed storage phosphor to produce a digital x-ray image. The digital x-ray image is analyzed by means of a computer algorithm which presents analytic results in text and graphical form to isolate reader problems and to quantify calibration status of the reader.