Patents by Inventor Daniel K. Yarbrough
Daniel K. Yarbrough has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10111926Abstract: The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial peptides having antimicrobial activities, and specifically/selectively targeted antimicrobial peptides (STAMPs). In addition, the present invention provides methods of selectively killing or inhibiting microbial organisms by using the peptides or compositions provided by the present invention.Type: GrantFiled: May 24, 2016Date of Patent: October 30, 2018Assignees: The Regents of the University of California, C3 Jian, LLCInventors: Randal H. Eckert, Daniel K. Yarbrough, Wenyuan Shi, Maxwell H. Anderson, Fengxia Qi, Jian He, Ian H. McHardy
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Publication number: 20170266306Abstract: This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species.Type: ApplicationFiled: February 15, 2017Publication date: September 21, 2017Inventors: RANDAL H. ECKERT, CHRIS KAPLAN, JIAN HE, DANIEL K. YARBROUGH, MAXWELL ANDERSON, JEE-HYUN SIM
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Patent number: 9597407Abstract: This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species.Type: GrantFiled: April 17, 2014Date of Patent: March 21, 2017Assignee: C3 JIAN, LLCInventors: Randal H. Eckert, Chris Kaplan, Jian He, Daniel K. Yarbrough, Maxwell Anderson, Jee-Hyun Sim
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Publication number: 20160331804Abstract: The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial peptides having antimicrobial activities, and specifically/selectively targeted antimicrobial peptides (STAMPs). In addition, the present invention provides methods of selectively killing or inhibiting microbial organisms by using the peptides or compositions provided by the present invention.Type: ApplicationFiled: May 24, 2016Publication date: November 17, 2016Applicant: C3 Jian, Inc.Inventors: Randal H. Eckert, Daniel K. Yarbrough, Wenyuan Shi, Maxwell H. Anderson, Fengxia Qi, Jian He, Ian H. McHardy
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Patent number: 9351490Abstract: The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial peptides having antimicrobial activities, and specifically/selectively targeted antimicrobial peptides (STAMPs). In addition, the present invention provides methods of selectively killing or inhibiting microbial organisms by using the peptides or compositions provided by the present invention.Type: GrantFiled: February 11, 2014Date of Patent: May 31, 2016Assignee: The Regents of the University of CaliforniaInventors: Randal H. Eckert, Daniel K. Yarbrough, Wenyuan Shi, Maxwell H. Anderson, Fengxia Qi, Jian He, Ian H. McHardy
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Patent number: 9072793Abstract: This invention provides novel antimicrobial peptides and formulations thereof. The peptides and/or formulations are effective to kill or to inhibit the growth and/or proliferation of various bacteria, yeast, and fungi.Type: GrantFiled: October 16, 2012Date of Patent: July 7, 2015Assignee: C3 Jian, Inc.Inventors: Randal H. Eckert, Chris Kaplan, Jian He, Daniel K. Yarbrough, Maxwell Anderson, Jee-Hyun Sim
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Publication number: 20150139907Abstract: This invention provides novel methods for inducing hair growth and/or inhibiting hair loss and/or inducing nail growth in a mammal. In various embodiments the methods involve administering, e.g., to a mammal in need thereof, a calcium-binding peptide and/or peptide-like moiety in an amount sufficient to induce hair growth and/or to inhibit hair loss. In certain embodiments the agent is topically and/or transdermally administered.Type: ApplicationFiled: October 14, 2014Publication date: May 21, 2015Inventors: Daniel K. Yarbrough, Xiaoyang Wu, Wenyuan Shi, Maxwell H. Anderson
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Publication number: 20140349917Abstract: This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species.Type: ApplicationFiled: April 17, 2014Publication date: November 27, 2014Applicant: C3 JIAN, INC.Inventors: RANDAL H. ECKERT, CHRIS KAPLAN, JIAN HE, DANIEL K. YARBROUGH, MAXWELL ANDERSON, JEE-HYUN SIM
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Patent number: 8889156Abstract: This invention provides novel methods for inducing hair growth and/or inhibiting hair loss and/or inducing nail growth in a mammal. In various embodiments the methods involve administering, e.g., to a mammal in need thereof, a calcium-binding peptide and/or peptide-like moiety in an amount sufficient to induce hair growth and/or to inhibit hair loss. In certain embodiments the agent is topically and/or transdermally administered.Type: GrantFiled: February 4, 2010Date of Patent: November 18, 2014Assignees: The Regents of the University of California, C3 Jian, Inc.Inventors: Daniel K. Yarbrough, Xiaoyang Wu, Wenyuan Shi, Maxwell Anderson
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Publication number: 20140314691Abstract: In various embodiments compositions are provided for the whitening, and/or brightening, and/or restoration of a tooth. In various embodiments the compositions, referred to herein as “dental care” compositions typically comprise a binding moiety that binds to calcium and/or to tooth enamel and/or to pellicle attached to an active agent. The active agent is selected to deliver a particular activity (e.g., whitening, remineralization, desensitization, brightening, etc.) to the tooth.Type: ApplicationFiled: March 11, 2014Publication date: October 23, 2014Applicant: C3 JIAN, INC.Inventors: Randal H. ECKERT, Daniel K. YARBROUGH, Brian C. VARNUM
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Patent number: 8754039Abstract: This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species.Type: GrantFiled: January 6, 2010Date of Patent: June 17, 2014Assignee: C3 Jian, Inc.Inventors: Randal H. Eckert, Chris Kaplan, Jian He, Daniel K. Yarbrough, Maxwell Anderson, Jee-Hyun Sim
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Publication number: 20140155317Abstract: The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial peptides having antimicrobial activities, and specifically/selectively targeted antimicrobial peptides (STAMPs). In addition, the present invention provides methods of selectively killing or inhibiting microbial organisms by using the peptides or compositions provided by the present invention.Type: ApplicationFiled: February 11, 2014Publication date: June 5, 2014Applicants: C3 JIAN, INC., THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Randal H. Eckert, Daniel K. Yarbrough, Wenyuan Shi, Maxwell H. Anderson, Fengxia Qi, Jian He, Ian H. McHardy
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Patent number: 8680058Abstract: The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial peptides having antimicrobial activities, and specifically/selectively targeted antimicrobial peptides (STAMPs). In addition, the present invention provides methods of selectively killing or inhibiting microbial organisms by using the peptides or compositions provided by the present invention.Type: GrantFiled: November 2, 2010Date of Patent: March 25, 2014Assignees: The Regents of the University of California, C3 Jian, Inc.Inventors: Randal H. Eckert, Daniel K. Yarbrough, Wenyuan Shi, Maxwell H. Anderson, Fengxia Qi, Jian He, Ian H. McHardy
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Patent number: 8303962Abstract: This invention provides novel antimicrobial peptides and formulations thereof. The peptides and/or formulations are effective to kill or to inhibit the growth and/or proliferation of various bacteria, yeast, and fungi.Type: GrantFiled: January 6, 2010Date of Patent: November 6, 2012Assignee: C3 Jian, Inc.Inventors: Randal H. Eckert, Chris Kaplan, Jian He, Daniel K. Yarbrough, Maxwell Anderson, Jee-Hyun Sim
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Publication number: 20120003661Abstract: Methods and devices are provided for the rapid and specific detection of target microorganisms, cells, and the like. In one embodiment, the methods involve contacting a target microorganism (e.g., in a sample) with a permeabilization reagent that selectively permeabilizes or lyses the microorganism; contacting the selectively permeabilized microorganism with a detection reagent that is taken into the selectively permeabilized organism or that contacts metabolites or enzymes released by the selectively permeabilized microorganism, where the detection reagent produces a signal in the presence of said metabolites or enzymes; and detecting a signal produced by the detection reagent in the presence of the metabolites or enzymes wherein the strength of the signal indicates the presence and/or amount of the target microorganism in the sample.Type: ApplicationFiled: June 27, 2011Publication date: January 5, 2012Applicant: C3 JIAN, INC.Inventors: Randal H. Eckert, Chris Kaplan, Jian He, Daniel K. Yarbrough, Maxwell Anderson, Jee-Hyun Sim
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Publication number: 20110207657Abstract: The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial peptides having antimicrobial activities, and specifically/selectively targeted antimicrobial peptides (STAMPs). In addition, the present invention provides methods of selectively killing or inhibiting microbial organisms by using the peptides or compositions provided by the present invention.Type: ApplicationFiled: November 2, 2010Publication date: August 25, 2011Inventors: Randal H. Eckert, Daniel K. Yarbrough, Wenyuan Shi, Fengxia Qi, Jian He, Ian H. McHardy, Maxwell H. Anderson
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Publication number: 20110039763Abstract: This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species.Type: ApplicationFiled: January 6, 2010Publication date: February 17, 2011Applicant: C3 JIAN, INC.Inventors: RANDAL H. ECKERT, CHRIS KAPLAN, JIAN HE, DANIEL K. YARBROUGH, MAXWELL ANDERSON, JEE-HYUN SIM
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Publication number: 20110039762Abstract: This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species.Type: ApplicationFiled: January 6, 2010Publication date: February 17, 2011Applicant: C3 JIAN, INC.Inventors: RANDAL H. ECKERT, CHRIS KAPLAN, JIAN HE, DANIEL K. YARBROUGH, MAXWELL ANDERSON, JEE-HYUN SIM
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Publication number: 20110039761Abstract: This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species.Type: ApplicationFiled: January 6, 2010Publication date: February 17, 2011Applicant: C3 JIAN, INC.Inventors: RANDAL H. ECKERT, CHRIS KAPLAN, JIAN HE, DANIEL K. YARBROUGH, MAXWELL ANDERSON, JEE-HYUN SIM
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Patent number: 7846895Abstract: The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial peptides having antimicrobial activities, and specifically/selectively targeted antimicrobial peptides (STAMPs). In addition, the present invention provides methods of selectively killing or inhibiting microbial organisms by using the peptides or compositions provided by the present invention.Type: GrantFiled: September 6, 2007Date of Patent: December 7, 2010Assignees: The Regents of the University of California, C3 Jian, Inc.Inventors: Randal H. Eckert, Daniel K. Yarbrough, Wenyuan Shi, Maxwell H. Anderson, Fengxia Qi, Jian He, Ian H. McHardy