Abstract: When a loan payment failure occurs, a loan server can retry a payment from a client's financial institution sources rather than immediately charging the client for the payment failure. The payment retry is scheduled on a Friday that is at least three days after the payment failure. If a payment failure from the financial institution sources to the loan server occurs between a Friday and the following Monday the payment retry by the loan server to the financial institution sources will occur on the first following Friday and if the payment failure occurs on Tuesday, Wednesday or Thursday, the payment retry will occur on the second following Friday which is the Friday of the following week from the failure date.

Abstract: When a loan payment failure occurs, a loan server can retry a payment from a client's financial institution sources rather than immediately charging the client for the payment failure. The payment retry is scheduled on a Friday that is at least three days after the payment failure. If a payment failure from the financial institution sources to the loan server occurs between a Friday and the following Monday the payment retry by the loan server to the financial institution sources will occur on the first following Friday and if the payment failure occurs on Tuesday, Wednesday or Thursday, the payment retry will occur on the second following Friday which is the Friday of the following week from the failure date.

Abstract: A system accesses a virtual scene including a three-dimensional (3D) object and a mesh object that models a cloth object. The system performs a refinement simulation to model a drape of the cloth object over the 3D object. Performing the refinement simulation includes, for each of a sequence of mesh resolutions: determining a configuration of the mesh model that minimizes a proxy energy function of a finest mesh resolution of the sequence of mesh resolutions. The system generates, for display via a user interface during the refinement simulation, an editable preview object comprising the mesh object at a coarsest level mesh resolution. The system receives a modification to the editable preview object and displays the modified editable preview object. A configuration of a finest level mesh resolution of the mesh object in the refinement simulation is geometrically consistent with a configuration of the modified editable preview object.

Abstract: When a loan payment failure occurs, a loan server can retry a payment from a client's financial institution sources rather than immediately charging the client for the payment failure. The payment retry is scheduled on a Friday that is at least three days after the payment failure. If a payment failure from the financial institution sources to the loan server occurs between a Friday and the following Monday the payment retry by the loan server to the financial institution sources will occur on the first following Friday and if the payment failure occurs on Tuesday, Wednesday or Thursday, the payment retry will occur on the second following Friday which is the Friday of the following week from the failure date.

Abstract: Embodiments methods of reducing an inflammatory immune response (e.g., inhibiting a Th1 response) and/or promoting a regulatory immune response (e.g., enhancing Treg(s)) in a mammal are provided where the method methods involve administering to the mammal a GABAA receptor positive allosteric modulator (PAM) in an amount sufficient to reduce an inflammatory immune response and/or to promote a regulatory immune response said mammal. In certain embodiments the PAM is administered in conjunction with a GABA receptor activating ligand (e.g., GABA).

Abstract: A system accesses a virtual scene including a three-dimensional (3D) object and a mesh object that models a cloth object. The system performs a refinement simulation to model a drape of the cloth object over the 3D object. Performing the refinement simulation includes, for each of a sequence of mesh resolutions: determining a configuration of the mesh model that minimizes a proxy energy function of a finest mesh resolution of the sequence of mesh resolutions. The system generates, for display via a user interface during the refinement simulation, an editable preview object comprising the mesh object at a coarsest level mesh resolution. The system receives a modification to the editable preview object and displays the modified editable preview object. A configuration of a finest level mesh resolution of the mesh object in the refinement simulation is geometrically consistent with a configuration of the modified editable preview object.

Abstract: When a loan payment failure occurs, a loan server can retry a payment from a client's financial institution sources rather than immediately charging the client for the payment failure. The payment retry is scheduled on a Friday that is at least three days after the payment failure. If a payment failure from the financial institution sources to the loan server occurs between a Friday and the following Monday the payment retry by the loan server to the financial institution sources will occur on the first following Friday and if the payment failure occurs on Tuesday, Wednesday or Thursday, the payment retry will occur on the second following Friday which is the Friday of the following week from the failure date.

Abstract: Embodiments of the disclosed technology are directed to classifying motion data collected by wearable sensors. Motion data collected by a first wearable motion sensor and a second wearable motion sensor during the performance of an activity can be obtained. The motion data from the first wearable motion sensor can include data associated with one or more first motion primitives and the second motion data collected by the second wearable motion sensor can include data associated with one or more second motion primitives. The first motion data and the second motion data can be synchronized based at least in part on time stamp information. Data associated with a signature motion classification associated with the activity can be determined based at least in part on the one or more first motion primitives and the one or more second motion primitives.

Abstract: Systems and methods provide for efficiently and accurately determining a simplified path that conforms to the geometry of an original path by simultaneously minimizing the deviation from the original path and reducing the number of anchor points in the simplified path. A simplified path may be iteratively generated by updating parametric values and anchor points for candidate simplified paths at epochs. A deviation in distance between points on the original path and corresponding points on candidate paths may be iteratively decreased to ensure that the resulting simplified path follows the geometry of the original path to a predetermined threshold. Continuity constrains can also be applied to ensure smoothness of the simplified path.

Abstract: Systems and methods for three-dimensional (3D) modeling are described. Embodiments of the inventive concept are configured to receive manipulation input for editing a scene in a static 3D modeling application, perform a physics simulation based on the manipulation input, wherein the physics simulation comprises a plurality of simulation steps performed based on a set of motion constraints configured for the static 3D modeling application, and apply a change to the scene in the static 3D modeling application based on the physics simulation.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for removing an anchor point from a Bezier spline while preserving the shape of the Bezier spline. For example, the disclosed systems can replace adjacent input segments of an initial Bezier spline that are connected at an anchor point with a new contiguous segment that does not include an anchor point and that spans the portion of the spline covered by the adjacent segments. The disclosed systems can utilize an objective function to determine tangent vectors that indicate locations of control points for generating the new segment to replace the adjacent segments. In addition, the disclosed systems can generate a modified Bezier spline that includes the new segment in place of the adjacent segments of the initial Bezier spline.

Abstract: Embodiments are disclosed for constrained modification of vector geometry. In particular, in one or more embodiments, the disclosed systems and methods comprise receiving a selection of a first segment of a vector graphic to be edited, identifying an active region associated with the first segment, wherein the active region includes the first segment and at least one second segment which comprise a geometric primitive, identifying the region of influence including at least one third segment connected to the active region, identifying at least one constraint associated with the active region or the region of influence based at least on the geometric primitive, receiving an edit to the active region, and generating an update for the vector graphic based on the edit and the at least one constraint.

Abstract: When a loan payment failure occurs, a loan server can retry a payment from a client's financial institution sources rather than immediately charging the client for the payment failure. The payment retry is scheduled on a Friday that is at least three days after the payment failure. If a payment failure from the financial institution sources to the loan server occurs between a Friday and the following Monday the payment retry by the loan server to the financial institution sources will occur on the first following Friday and if the payment failure occurs on Tuesday, Wednesday or Thursday, the payment retry will occur on the second following Friday which is the Friday of the following week from the failure date.

Abstract: Embodiments are disclosed for constrained modification of vector geometry. In particular, in one or more embodiments, the disclosed systems and methods comprise receiving a selection of a first segment of a vector graphic to be edited, identifying an active region associated with the first segment, wherein the active region includes the first segment and at least one second segment which comprise a geometric primitive, identifying the region of influence including at least one third segment connected to the active region, identifying at least one constraint associated with the active region or the region of influence based at least on the geometric primitive, receiving an edit to the active region, and generating an update for the vector graphic based on the edit and the at least one constraint.

Abstract: When a loan payment failure occurs, a loan server can retry a payment from a client's financial institution sources rather than immediately charging the client for the payment failure. The payment retry is scheduled on a Friday that is at least three days after the payment failure. If a payment failure from the financial institution sources to the loan server occurs between a Friday and the following Monday the payment retry by the loan server to the financial institution sources will occur on the first following Friday and if the payment failure occurs on Tuesday, Wednesday or Thursday, the payment retry will occur on the second following Friday which is the Friday of the following week from the failure date.

Abstract: Systems and methods for three-dimensional (3D) modeling are described. Embodiments of the inventive concept are configured to receive manipulation input for editing a scene in a static 3D modeling application, perform a physics simulation based on the manipulation input, wherein the physics simulation comprises a plurality of simulation steps performed based on a set of motion constraints configured for the static 3D modeling application, and apply a change to the scene in the static 3D modeling application based on the physics simulation.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for removing an anchor point from a Bezier spline while preserving the shape of the Bezier spline. For example, the disclosed systems can replace adjacent input segments of an initial Bezier spline that are connected at an anchor point with a new contiguous segment that does not include an anchor point and that spans the portion of the spline covered by the adjacent segments. The disclosed systems can utilize an objective function to determine tangent vectors that indicate locations of control points for generating the new segment to replace the adjacent segments. In addition, the disclosed systems can generate a modified Bezier spline that includes the new segment in place of the adjacent segments of the initial Bezier spline.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for removing an anchor point from a Bezier spline while preserving the shape of the Bezier spline. For example, the disclosed systems can replace adjacent input segments of an initial Bezier spline that are connected at an anchor point with a new contiguous segment that does not include an anchor point and that spans the portion of the spline covered by the adjacent segments. The disclosed systems can utilize an objective function to determine tangent vectors that indicate locations of control points for generating the new segment to replace the adjacent segments. In addition, the disclosed systems can generate a modified Bezier spline that includes the new segment in place of the adjacent segments of the initial Bezier spline.

Abstract: The present application relates to a combination therapy for treatment of inflammatory diseases comprising an immunomodulator compound and a GABA-receptor agonist in an amount effective to reduce inflammation and ameliorate disease. In certain embodiments, the present application relates to treatment of T1D by administering an immunomodulator compound and a GABA-receptor agonist in an amount effective to prevent, reduce, and/or treat hyperglycemia in the human or animal subject. In certain embodiments, the immunomodulator compound and GABA-receptor agonist are administered in an amount effective to control autoimmune responses and safely increase ?-cell mass and function in the context of established ?-cell autoimmunity.

Abstract: Systems and methods for editing an image based on multiple constraints are described. Embodiments of the systems and methods may identify a change to a vector graphics data structure, generate an update for the vector graphics data structure based on strictly enforcing a handle constraint, a binding constraint, and a continuity constraint, adjust the vector graphics data structure sequentially for each of a plurality of sculpting constraints according to a priority ordering of the sculpting constraints, generate an additional update for the vector graphics data structure based on strictly enforcing the binding constraint and the continuity constraint and approximately enforcing the handle constraint and the sculpting constraints, adjust the vector graphics data structure sequentially for each of a plurality of sculpting constraints, and display the vector graphic based on the adjusted vector graphics data structure.