Patents by Inventor Daniel Kenneth Bonner
Daniel Kenneth Bonner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11975073Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: June 26, 2023Date of Patent: May 7, 2024Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Rishab R. Shyam, Jamie Simpson, Christopher John Porter, Natalie Trevaskis, Tim Quach, Sifei Han, Luojuan Hu
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Patent number: 11938137Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: January 27, 2022Date of Patent: March 26, 2024Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
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Patent number: 11883497Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: August 29, 2018Date of Patent: January 30, 2024Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, James T. Mutamba, Rishab R. Shyam, Jamie Simpson, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Natalie Trevaskis
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Publication number: 20230338552Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: June 26, 2023Publication date: October 26, 2023Applicants: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Rishab R. Shyam, Jamie Simpson, Christopher John Porter, Natalie Trevaskis, Tim Quach, Sifei Han, Luojuan Hu
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Patent number: 11608345Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: December 19, 2018Date of Patent: March 21, 2023Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Sifei Han, Luojuan Hu, Ketki Karanam, Christopher John Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
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Publication number: 20230062834Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: December 19, 2018Publication date: March 2, 2023Inventors: Daniel Kenneth BONNER, Sifei HAN, Luojuan HU, Ketki KARANAM, Christopher John PORTER, Tim QUACH, Rishab R. SHYAM, Jamie SIMPSON, Natalie TREVASKIS
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Publication number: 20220395513Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: August 4, 2022Publication date: December 15, 2022Applicants: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Rishab R. Shyam, Jamie Simpson, Christopher John Porter, Natalie Trevaskis, Tim Quach, Sifei Han, Luojuan Hu
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Publication number: 20220143038Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: January 27, 2022Publication date: May 12, 2022Applicants: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
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Publication number: 20220125933Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: February 28, 2020Publication date: April 28, 2022Inventors: Joseph BOLEN, Daniel Kenneth BONNER, Ketki KARANAM, Christopher John PORTER, Jamie SIMPSON, Natalie TREVASKIS, Dan ZHENG, Nathania LEONG, Garima SHARMA, Mitchell MCINERNEY, Tim QUACH, Sifei HAN
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Patent number: 11304954Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: GrantFiled: December 19, 2018Date of Patent: April 19, 2022Assignees: PureTech LYT, Inc., Monash UniversityInventors: Daniel Kenneth Bonner, Ketki Karanam, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Rishab R. Shyam, Jamie Simpson, Natalie Trevaskis
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Publication number: 20220001015Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: August 29, 2018Publication date: January 6, 2022Inventors: Daniel Kenneth Bonner, Ketki Karanam, James T. Mutamba, Rishab R. Shyam, Jamie Simpson, Sifei Han, Luojuan Hu, Christopher John Hamilton Porter, Tim Quach, Natalie Trevaskis
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Publication number: 20210300962Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: August 2, 2019Publication date: September 30, 2021Inventors: Daniel Kenneth BONNER, Ketki KARANAM, Jamie SIMPSON, Christopher John PORTER, Natalie TREVASKIS, Tim QUACH, Sifei HAN, Luojuan HU
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Publication number: 20210268115Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: February 5, 2021Publication date: September 2, 2021Inventors: Daniel Kenneth BONNER, Rishab R. SHYAM, Jamie SIMPSON, Christopher John PORTER, Natalie TREVASKIS, Tim QUACH, Sifei HAN, Luojuan HU
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Publication number: 20210177757Abstract: The present invention provides exosomes as drug delivery vehicles, compositions comprising a therapeutic agent encapsulated within such exosomes, methods of producing such exosomes and compositions thereof, as well as methods of delivering such exosomes and compositions to a specific patient tissue or organ. The present invention also provides methods of treating a disease, disorder, or condition such as cancer, an inflammatory disease, an infectious disease, an allergic disease, or an autoimmune disease, comprising administering to a patient in need thereof a provided therapeutic-loaded exosome or a pharmaceutical composition thereof.Type: ApplicationFiled: July 29, 2020Publication date: June 17, 2021Applicant: PURETECH LYT, INC.Inventors: Joseph Bolen, Daniel Kenneth Bonner, Lisa V. Ferreira, Katerina Krumova, John Jantz, James Tendai Mutamba, Rishab R. Shyam
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Publication number: 20200390777Abstract: The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.Type: ApplicationFiled: December 19, 2018Publication date: December 17, 2020Inventors: Daniel Kenneth BONNER, Ketki KARANAM, Sifei HAN, Luojuan HU, Christopher John Hamilton PORTER, Tim QUACH, Rishab R. SHYAM, Jamie SIMPSON, Natalie TREVASKIS
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Publication number: 20180193270Abstract: The present invention provides exosomes as drug delivery vehicles, compositions comprising a therapeutic agent encapsulated within such exosomes, methods of producing such exosomes and compositions thereof, as well as methods of delivering such exosomes and compositions to a specific patient tissue or organ. The present invention also provides methods of treating a disease, disorder, or condition such as cancer, an inflammatory disease, an infectious disease, an allergic disease, or an autoimmune disease, comprising administering to a patient in need thereof a provided therapeutic-loaded exosome or a pharmaceutical composition thereof.Type: ApplicationFiled: November 29, 2017Publication date: July 12, 2018Inventors: Joseph Bolen, Daniel Kenneth Bonner, Lisa V. Ferreira, Katerina Krumova, John Jantz, James Tendai Mutamba, Rishab R. Shyam