Patents by Inventor DANIEL KITA

DANIEL KITA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody and antigen-binding fragment compositions targeting cell surface antigens in tumors and methods of use thereof
    Patent number: 11459381
    Abstract: Described herein is an isolated antibody or antigen-binding fragment including a heavy chain variable region including three heavy chain complementary determining regions (HCDRs), wherein the sequence of HCDR1 is GYRLSELS (SEQ ID NO: 1), the sequence of HCDR2 is ISGWDGNT (SEQ ID NO: 2), and the sequence of HCDR3 is ARASGYNY (SEQ ID NO: 3), wherein the isolated antibody or antigen-binding fragment specifically binds human HSP90, specifically HSP90 beta. Also included are detection and therapeutic methods using the isolated antibodies or antigen-binding fragments.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: October 4, 2022
    Assignee: UNIVERSITY OF CONNECTICUT
    Inventors: Kevin P. Claffey, Charan Devarakonda, Daniel Kita
  • ANTIBODY AND ANTIGEN-BINDING FRAGMENT COMPOSITIONS TARGETING CELL SURFACE ANTIGENS IN TUMORS AND METHODS OF USE THEREOF
    Publication number: 20190375830
    Abstract: Described herein is an isolated antibody or antigen-binding fragment including a heavy chain variable region including three heavy chain complementary determining regions (HCDRs), wherein the sequence of HCDR1 is GYRLSELS (SEQ ID NO: 1), the sequence of HCDR2 is ISGWDGNT (SEQ ID NO: 2), and the sequence of HCDR3 is ARASGYNY (SEQ ID NO: 3), wherein the isolated antibody or antigen-binding fragment specifically binds human HSP90, specifically HSP90 beta. Also included are detection and therapeutic methods using the isolated antibodies or antigen-binding fragments.
    Type: Application
    Filed: August 7, 2019
    Publication date: December 12, 2019
    Inventors: KEVIN P. CLAFFEY, CHARAN DEVARAKONDA, DANIEL KITA
  • Antibody and antigen-binding fragment compositions targeting cell surface antigens in tumors and methods of use thereof
    Patent number: 10457726
    Abstract: Described herein is an isolated antibody or antigen-binding fragment including a heavy chain variable region including three heavy chain complementary determining regions (HCDRs), wherein the sequence of HCDR1 is GYRLSELS (SEQ ID NO: 1), the sequence of HCDR2 is ISGWDGNT (SEQ ID NO: 2), and the sequence of HCDR3 is ARASGYNY(SEQ ID NO: 3), wherein the isolated antibody or antigen-binding fragment specifically binds human HSP90, specifically HSP90 beta. Also included are detection and therapeutic methods using the isolated antibodies or antigen-binding fragments.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: October 29, 2019
    Assignee: UNIVERSITY OF CONNECTICUT
    Inventors: Kevin P. Claffey, Charan Devarakonda, Daniel Kita
  • ANTIBODY AND ANTIGEN-BINDING FRAGMENT COMPOSITIONS TARGETING CELL SURFACE ANTIGENS IN TUMORS AND METHODS OF USE THEREOF
    Publication number: 20180002412
    Abstract: Described herein is an isolated antibody or antigen-binding fragment including a heavy chain variable region including three heavy chain complementary determining regions (HCDRs), wherein the sequence of HCDR1 is GYRLSELS (SEQ ID NO: 1), the sequence of HCDR2 is ISGWDGNT (SEQ ID NO: 2), and the sequence of HCDR3 is ARASGYNY(SEQ ID NO: 3), wherein the isolated antibody or antigen-binding fragment specifically binds human HSP90, specifically HSP90 beta. Also included are detection and therapeutic methods using the isolated antibodies or antigen-binding fragments.
    Type: Application
    Filed: June 29, 2017
    Publication date: January 4, 2018
    Inventors: KEVIN P. CLAFFEY, CHARAN DEVARAKONDA, DANIEL KITA