Patents by Inventor Daniel Klein

Daniel Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130059299
    Abstract: The present invention provides novel mitochondrial fusion transcripts, the parent mutated mtDNA molecules, and the resulting translation products (proteins) for predicting, diagnosing and/or monitoring cancer. Hybridization probes complementary thereto for use in the methods of the invention are also provided.
    Type: Application
    Filed: March 29, 2010
    Publication date: March 7, 2013
    Applicant: MITOMICS INC.
    Inventors: Ryan Parr, Andrew Harbottle, Brian Reguly, Jennifer Creed, Kerry Robinson, Daniel Klein
  • Publication number: 20120263105
    Abstract: The invention relates to a radio network comprising a plurality of first clients which can communicate with one another by means of radio waves, wherein the first clients have at least one input unit for the input of data and/or at least one output unit for the output of data, wherein a first reference can be adjusted on one input unit and a second reference can be adjusted on one output unit, wherein the radio network is configured such that the incoming data to the input unit is communicated to the one or more output units the second reference thereof corresponding with the first reference adjusted on the input unit.
    Type: Application
    Filed: September 17, 2010
    Publication date: October 18, 2012
    Applicant: PHOENIX CONTACT GMBH & CO. KG
    Inventors: Frank Hakemeyer, Daniel Klein, Andreas Senger
  • Publication number: 20120153232
    Abstract: The thermoplastic molding composition comprises, based on the thermoplastic molding composition, a) as component A, at least one polyamide or copolyamide, or one polymer blend comprising polyamide, b) as component B, from 3 to 20% by weight of carbon black or graphite, or a mixture thereof, c) as component C, from 0.1 to 3% by weight of ionic liquids.
    Type: Application
    Filed: December 13, 2011
    Publication date: June 21, 2012
    Applicant: BASF SE
    Inventors: Cecile Gibon, Xin Yang, Christof Kujat, Martin Weber, Laszlo Szarvas, Daniel Klein, Petra Poetschke, Beate Krause
  • Publication number: 20120153233
    Abstract: The thermoplastic molding composition comprises, based on the thermoplastic molding composition, a) at least one polyamide, copolyamide or a polyamide-comprising polymer blend as component A, b) from 0.1 to 10% by weight of carbon nanotubes, graphenes or mixtures thereof as component B, c) from 0.1 to 3% by weight of ionic liquids as component C, wherein the thermoplastic molding composition does not comprise any polyamide-12 units.
    Type: Application
    Filed: December 21, 2011
    Publication date: June 21, 2012
    Applicant: BASF SE
    Inventors: Cecile Gibon, Xin Yang, Christof Kujat, Martin Weber, Laszlo Szarvas, Daniel Klein, Petra Poetschke, Beate Krause
  • Patent number: 8193314
    Abstract: The invention relates to global transcription machinery engineering to produce altered cells having improved phenotypes and methods for evaluating phenotypic diversity.
    Type: Grant
    Filed: July 10, 2008
    Date of Patent: June 5, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Gregory Stephanopoulos, Daniel Klein-Marcuschamer
  • Publication number: 20120108593
    Abstract: An extreme temperature decontamination composition such as a solution for destroying microorganisms, chemical warfare and bioterrorism agents is utilized that generally does not freeze at low temperatures down to about minus 25° F. and also has no significant evaporation or decomposition at temperatures up to about 120° F. The solution is effective against nerve agents and vesicants such as VX and HD, and various biological agents. The composition comprises a metallic salt of dichloroisocyanuric acid or dibromoisocyanuric acid, an aqueous solvent system comprising polar compounds such as water and an alkyl glycol, and a quasi hydrophilic compound. The composition can be formulated as a one part system wherein all components are blended together.
    Type: Application
    Filed: August 19, 2010
    Publication date: May 3, 2012
    Applicant: AMERICAN STERILIZER COMPANY
    Inventors: Herbert J. Kaiser, Daniel A. Klein, Anchalee Thanavaro, Miranda Chevon Shaver
  • Publication number: 20110269198
    Abstract: The invention pertains to a method for preparing cells that can be used as biocatalysts by inducing in them a growth-decoupled state, in which interferase inhibits the expression of genes except the ones that code for the pathway enzymes of interest. mRNAs that code for interferase-resistant products are overexpressed in the background of a metabolically-frozen cell. Enzymes that compete for a substrate or product of the pathway of interest may be altered such that the enzyme is sensitive to a site-specific protease, which protease is inducible in the host cell.
    Type: Application
    Filed: December 14, 2009
    Publication date: November 3, 2011
    Applicant: GREENLIGHT BIOSCIENCES, INC.
    Inventor: Daniel Klein-Marcuschamer
  • Patent number: 7985773
    Abstract: Antimicrobial compositions which can be used wherever disinfecting compositions are needed, such as in a hospital, healthcare industry, workplace, recreational facility, home or similar environment. The antimicrobial compositions are particularly useful as a topical application for a substrate, such as skin and can be used as a hand sanitizer or pre-surgical scrub. The compositions comprise a synergistic combination of a simple aliphatic alcohol and an activity enhancing substance, wherein the composition provides, heretofore unexpected, persistent activity against a broad range of microorganisms, including gram-negative organisms, while moisturizing the skin.
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: July 26, 2011
    Assignee: American Sterilizer Company
    Inventors: Zachariah C. Greten, Nancy-Hope E. Kaiser, Daniel A. Klein
  • Patent number: 7945437
    Abstract: Systems and methods for using automated translation and other statistical methods to convert a classifier in one language to another language are provided. In one embodiment of the invention, a method preferably includes marking target language examples of passages of text in order to obtain an initial classifier in the target language, re-classifying a plurality of target language examples in the initial classifier, and then questioning—i.e., determining the validity—of the marking used to obtain the initial classifier. Preferably, the questioning is based on the re-classifying. Then, preferably following the questioning, the method isolates a high-quality set of target examples based on the results of the questioning. Finally, the method uses the high-quality set of target examples to prepare a high-quality classifier in the target language.
    Type: Grant
    Filed: January 31, 2006
    Date of Patent: May 17, 2011
    Assignee: Shopping.com
    Inventors: John Mount, Amir Ashkenazi, Daniel Klein, Teg Grenager
  • Publication number: 20100330614
    Abstract: The invention relates to global transcription machinery engineering to produce altered cells having improved phenotypes.
    Type: Application
    Filed: November 6, 2008
    Publication date: December 30, 2010
    Applicant: Massachusetts Institute of Technology
    Inventors: Gregory Stephanopoulos, Daniel Klein-Marcuschamer, Hal S. Alper
  • Patent number: 7838485
    Abstract: An aqueous, alkaline cleaning composition for use on hard-to-clean soils, encountered in pharmaceutical, personal care, food and cosmetic manufacturing, comprising a source of alkalinity, a biodegradable surfactant system further comprising one or more surfactants, one or more hydrotropes, and a UV-analyzable surfactant, and a biodegradable chelating agent. The composition offers unique advantages of stability over the expected shelf life, low-foaming property, phosphate-free and biodegradable components, and unexpectedly enhanced antimicrobial, including virucidal, activity in one cleaning composition. The UV-analyzable surfactant allows for validation of cleaning processes using known techniques for manufacturers who are required or desire to do so.
    Type: Grant
    Filed: March 8, 2007
    Date of Patent: November 23, 2010
    Assignee: American Sterilizer Company
    Inventors: Christopher C. Heisig, Shahin Keller, John Macauley, Gurusamy Manivannan, Daniel Klein, Michael Ebers
  • Patent number: 7814930
    Abstract: A liquid refill control for a holding tank includes a pneumatic solenoid valve for delivering liquid to the tank in an open state and restricting delivery of the liquid to the tank in a closed state. The solenoid valve has a pneumatic exhaust. A container mounted in the tank includes an inlet for introducing liquid from the tank into the container and an outlet formed below the inlet. A discharge valve is operably mounted to the tank for alternately closing and opening the outlet. A lower float closes the discharge valve when the liquid is at or above a predetermined level in the tank and opens the discharge valve when the liquid is below the predetermined level to discharge liquid from the container. A pneumatic exhaust valve alternately opens and closes the pneumatic exhaust which in turn changes the state of the pneumatic solenoid valve.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: October 19, 2010
    Assignee: Action Manufacturing & Supply, Inc.
    Inventors: Richard J. Shepherd, Daniel A. Klein
  • Publication number: 20100196503
    Abstract: A low odor, liquid disinfectant composition comprising multiple components, which, upon mixing, provide an aqueous solution comprising low levels of peracetic acid for use in decontaminating articles and surfaces contaminated with bacteria, viruses, fungi and other biological contaminants such as spores, including, but not limited to, Clostridium difficile (C.diff). The disinfectant composition is prepared just prior to use by combining two or more separately packaged components.
    Type: Application
    Filed: February 5, 2009
    Publication date: August 5, 2010
    Applicant: American Sterilizer Company
    Inventors: Christopher C. Heisig, Herbert J. Kaiser, Daniel A. Klein, Jessica S. Linder, Katie J. Frey, Nancy E. Kaiser, Jerry L. Newman
  • Publication number: 20100138452
    Abstract: Various techniques are disclosed for facilitating on-line contextual analysis and/or advertising operations implemented in a computer network. According to some embodiments, various aspects may be used for enabling advertisers to provide contextual advertising promotions to end-users based upon real-time analysis of web page content which may be served to an end-user's computer system. In at least one embodiment, the information obtained from the real-time analysis may be used to select, in real-time, contextually relevant information, advertisements, and/or other content which may then be displayed to the end-user, for example, via real-time insertion of textual markup objects and/or dynamic content.
    Type: Application
    Filed: August 10, 2007
    Publication date: June 3, 2010
    Inventors: Assaf Henkin, Yoav Shaham, Itai Brickner, Trond Grenager, Daniel Klein
  • Publication number: 20100138271
    Abstract: Various techniques are disclosed for facilitating on-line contextual analysis and/or advertising operations implemented in a computer network. According to some embodiments, various aspects may be used for enabling advertisers to provide contextual advertising promotions to end-users based upon real-time analysis of web page content which may be served to an end-user's computer system. In at least one embodiment, the information obtained from the real-time analysis may be used to select, in real-time, contextually relevant information, advertisements, and/or other content which may then be displayed to the end-user, for example, via real-time insertion of textual markup objects and/or dynamic content.
    Type: Application
    Filed: August 10, 2007
    Publication date: June 3, 2010
    Inventors: Assaf Henkin, Yoav Shaham, Itai Brickner, Trond Grenager, Daniel Klein
  • Publication number: 20100138451
    Abstract: Various techniques are disclosed for facilitating on-line contextual analysis and/or advertising operations implemented in a computer network. According to some embodiments, various aspects may be used for enabling advertisers to provide contextual advertising promotions to end-users based upon real-time analysis of web page content which may be served to an end-user's computer system. In at least one embodiment, the information obtained from the real-time analysis may be used to select, in real-time, contextually relevant information, advertisements, and/or other content which may then be displayed to the end-user, for example, via real-time insertion of textual markup objects and/or dynamic content.
    Type: Application
    Filed: April 3, 2007
    Publication date: June 3, 2010
    Inventors: Assaf Henkin, Yoav Shaham, Itai Brickner, Trond Grenager, Daniel Klein
  • Patent number: 7638063
    Abstract: Contaminants are removed from fluid in a system where the fluid is sprayed into an air head at the top of a tank through a diffuser and withdrawn through a pick-up tube. A solenoid valve operates to allow oxygen-containing gas from a compressed gas source to flow into the tank through a shuttle valve, which is opened by the gas pressure. Simultaneously, a drain valve connected to the shuttle valve opens a drain, venting water and air from the tank. The solenoid valve also operates to close the gas supply line and connect the shuttle valve through a vent to atmosphere. Pressure within the tank closes the shuttle valve, which in turn closes the drain valve and disconnects the shuttle valve from the tank. A one-way-flow valve prevents fluid or gas from flowing from the tank backwards through the shuttle valve to the solenoid valve and out the vent.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: December 29, 2009
    Assignee: Hellenbrand, Inc.
    Inventors: Edward T. Maas, Paul A. Beres, Kevin A. Hellenbrand, William M. Kavey, Daniel A. Klein
  • Publication number: 20090176659
    Abstract: The invention relates to global transcription machinery engineering to produce altered cells having improved phenotypes and methods for evaluating phenotypic diversity.
    Type: Application
    Filed: July 10, 2008
    Publication date: July 9, 2009
    Applicant: Massachusetts Institute of Technology
    Inventors: Gregory Stephanopoulos, Daniel Klein-Marcuschamer
  • Patent number: 7491321
    Abstract: Contaminants are removed from fluid in a system where the fluid is sprayed into an air head at the top of a tank through a diffuser and withdrawn through a pick-up tube. A solenoid valve operates to allow oxygen-containing gas from a compressed gas source to flow into the tank through a shuttle valve, which is opened by the gas pressure. Simultaneously, a drain valve connected to the shuttle valve opens a drain, venting water and air from the tank. The solenoid valve also operates to close the gas supply line and connect the shuttle valve through a vent to atmosphere. Pressure within the tank closes the shuttle valve, which in turn closes the drain valve and disconnects the shuttle valve from the tank. A one-way-flow valve prevents fluid or gas from flowing from the tank backwards through the shuttle valve to the solenoid valve and out the vent.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: February 17, 2009
    Assignee: Hellenbrand, Inc.
    Inventors: Edward T. Maas, Paul A. Beres, Kevin A. Hellenbrand, William M. Kavey, Daniel A. Klein
  • Publication number: 20080221006
    Abstract: An aqueous, alkaline cleaning composition for use on hard-to-clean soils, encountered in pharmaceutical, personal care, food and cosmetic manufacturing, comprising a source of alkalinity, a biodegradable surfactant system further comprising one or more surfactants, one or more hydrotropes, and a UV-analyzable surfactant, and a biodegradable chelating agent. The composition offers unique advantages of stability over the expected shelf life, low-foaming property, phosphate-free and biodegradable components, and unexpectedly enhanced antimicrobial, including virucidal, activity in one cleaning composition. The UV-analyzable surfactant allows for validation of cleaning processes using known techniques for manufacturers who are required or desire to do so.
    Type: Application
    Filed: March 8, 2007
    Publication date: September 11, 2008
    Inventors: Christopher C. Heisig, Shahin Keller, John Macauley, Gurusamy Manivannan, Daniel Klein, Michael Ebers