Patents by Inventor Daniel Kroon

Daniel Kroon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunoglobulin-binding polypeptides
    Patent number: 5306812
    Abstract: A method of separating V.sub.H containing immunoglobulins by admixing an immunoglobulin binding peptide is described. The polypeptide of the invention is capable of binding to heavy chain variable regions of antibodies in an antigen independent manner and can separate antigen/antibody complexes.
    Type: Grant
    Filed: June 20, 1990
    Date of Patent: April 26, 1994
    Assignee: The Regents of the University of California
    Inventors: Maurizio Zanetti, Petar Lenert, Edward Golub, Daniel Kroon
  • Immunoglobulin-binding polypeptides
    Patent number: 5231167
    Abstract: Polypeptides having a segment capable of binding to immunoglobulin heavy chain variable regions (V.sub.H) in an antigen independent manner have been described. These polypeptides can be used to form complexes with V.sub.M containing molecules for diagnostic purposes and to increase the affinity of the antibody for its antigen. Additionally, the polypeptides of the invention can be used to separate V.sub.H containing molecules from solution to form isolated V.sub.H or V.sub.H depleted compositions.
    Type: Grant
    Filed: September 8, 1989
    Date of Patent: July 27, 1993
    Assignee: The Regents of the University of California
    Inventors: Maurizio Zanetti, Petar Lenert, Edward Golub, Daniel Kroon
  • Potent thymopentin analogs
    Patent number: 4629723
    Abstract: Immunoregulating peptides are disclosed which are more potent than thymopentin or splenin and are useful for their effects on the immune system, especially the treatment of thymic deficiencies.
    Type: Grant
    Filed: June 27, 1984
    Date of Patent: December 16, 1986
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Gideon Goldstein, George Heavner, Daniel Kroon, Tapan Audhya
  • Enzyme-resistant immunomodulatory peptides
    Patent number: 4505853
    Abstract: Peptides which have thymopoeitin-like or splenin-like activity combined with greatly increased resistance to degradation by enzymes. The peptides are useful for treatment of immunoregulatory disorders. Also provided are methods of treating immunoregulatory disorders and compositions used in these methods.
    Type: Grant
    Filed: November 18, 1983
    Date of Patent: March 19, 1985
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Gideon Goldstein, George Heavner, Daniel Kroon, Tapan Audhya
  • Potent thymopentin analogs
    Patent number: RE34165
    Abstract: Immunoregulating peptides are disclosed which are more potent than thymopentin or splenin and are useful for their effects on the immune system, especially the treatment of thymic deficiencies.
    Type: Grant
    Filed: April 25, 1990
    Date of Patent: January 19, 1993
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Gideon Goldstein, George Heavner, Daniel Kroon, Tapan Audhya