Abstract: A system (10) for sensing a condition of a rail vehicle undercarriage component (e.g., 18) includes a sensor (e.g., 12) comprising an array of infrared sensing elements (29). Each of the elements may be aimed at a different region of a target area (e.g., 32) of a rail vehicle undercarriage component to generate respective scanning waveform signature data corresponding to each different region. The sensor may be oriented so that at least one of the elements receives unobstructed infrared emissions (e.g., 33) from the undercarriage component of a rail vehicle passing the sensor. The system also includes a memory (42) for storing characteristic waveform signature data corresponding to known undercarriage components.

Abstract: Imaging agents of formula (I) and methods for detecting neurological disorders comprising administering to a patient in need compounds of formula (I) capable of binding to tau proteins and ?-amyloid peptides are presented herein. The invention also relates to methods of imaging A? and tau aggregates comprising introducing a detectable quantity of pharmaceutical formulation comprising a radiolabeled compound of formula (I) and detecting the labeled compound associated with amyloid deposits and/or tau proteins in a patient. These methods and compositions enable preclinical diagnosis and monitoring progression of AD and other neurological disorders.

Abstract: Imaging agents of formula (I) and methods for detecting neurological disorders comprising administering ti a patient in need compounds of formula (I) capable of binding to tau proteins and ?-amyloid peptides are presented herein. The invention also relates to methods of imaging A? and tau aggregates comprising introducing a detectable quantity of pharmaceutical formulation comprising a radiolabeled compound of formula (I) and detecting the labeled compound associated with amyloid deposits and/or tau proteins in a patient. These methods and compositions enable preclinical diagnosis and monitoring progression of AD and other neurological disorders.

Abstract: A system (10) for sensing a condition of a rail vehicle undercarriage component (e.g., 18) includes a sensor (e.g., 12) comprising an array of infrared sensing elements (29). Each of the elements may be aimed at a different region of a target area (e.g., 32) of a rail vehicle undercarriage component to generate respective scanning waveform signature data corresponding to each different region. The sensor may be oriented so that at least one of the elements receives unobstructed infrared emissions (e.g., 33) from the undercarriage component of a rail vehicle passing the sensor. The system also includes a memory (42) for storing characteristic waveform signature data corresponding to known undercarriage components.

Abstract: Imaging agents of formulas (I)-(V) and methods for detecting neurological disorders comprising administering to a patient in need compounds of formulas (I)-(V) capable of binding to tau proteins and ?-amyloid peptides are presented herein. The invention also relates to methods of imaging A? and tau aggregates comprising introducing a detectable quantity of pharmaceutical formulation comprising a radiolabeled compound of formulas (I)-(V) and detecting the labeled compound associated with amyloid deposits and/or tau proteins in a patient. These methods and compositions enable preclinical diagnosis and monitoring progression of AD and other neurological disorders.

Abstract: Imaging agents of formula (I) and methods for detecting neurological disorders comprising administering to a patient in need compounds of formula (I) capable of binding to tau proteins and ?-amyloid peptides are presented herein. The invention also relates to methods of imaging A? and tau aggregates comprising introducing a detectable quantity of pharmaceutical formulation comprising a radiolabeled compound of formula (I) and detecting the labeled compound associated with amyloid deposits and/or tau proteins in a patient. These methods and compositions enable preclinical diagnosis and monitoring progression of AD and other neurological disorders.

Abstract: A system (10) for sensing a condition of a rail vehicle undercarriage component (e.g., 18) includes a sensor (e.g., 12) comprising an array of infrared sensing elements (29). Each of the elements may be aimed at a different region of a target area (e.g., 32) of a rail vehicle undercarriage component to generate respective scanning waveform signature data corresponding to each different region. The sensor may be oriented so that at least one of the elements receives unobstructed infrared emissions (e.g., 33) from the undercarriage component of a rail vehicle passing the sensor. The system also includes a memory (42) for storing characteristic waveform signature data corresponding to known undercarriage components.

Abstract: A high level shader language compiler incorporates transforms to optimize shader code for graphics processing hardware. An instruction reordering transform determines instruction encapsulations of dependent instructions that reduce concurrent register usage by the shader. A phase pulling transform re-organizes the shader's instructions into phases that reduce a measure of depth of texture loads. A register assigning transform assigns registers to lower register usage by the shader.

Abstract: A high level shader language compiler incorporates transforms to optimize shader code for graphics processing hardware. An instruction reordering transform determines instruction encapsulations of dependent instructions that reduce concurrent register usage by the shader. A phase pulling transform re-organizes the shader's instructions into phases that reduce a measure of depth of texture loads. A register assigning transform assigns registers to lower register usage by the shader.

Abstract: A high level shader language compiler incorporates transforms to optimize shader code for graphics processing hardware. An instruction reordering transform determines instruction encapsulations of dependent instructions that reduce concurrent register usage by the shader. A phase pulling transform re-organizes the shader's instructions into phases that reduce a measure of depth of texture loads. A register assigning transform assigns registers to lower register usage by the shader.