Patents by Inventor Daniel L. Siegel

Daniel L. Siegel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1?-cyano nucleoside analogs and uses thereof
    Patent number: 11939347
    Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
    Type: Grant
    Filed: June 23, 2021
    Date of Patent: March 26, 2024
    Assignee: Gilead Sciences, Inc.
    Inventors: Daniel H. Byun, Byoung-Kwon Chun, Michael O. Clarke, Petr Jansa, Rao V. Kalla, Dmitry Koltun, Richard L. Mackman, Thao D. Perry, Dustin S. Siegel, Scott P. Simonovich
  • Compositions comprising fibrous polypeptides and polysaccharides
    Patent number: 9815874
    Abstract: Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: November 14, 2017
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., CollPlantLtd.
    Inventors: Oded Shoseyov, Shaul Lapidot, Sigal Meirovitch, Daniel L. Siegel
  • COMPOSITIONS COMPRISING FIBROUS POLYPEPTIDES AND POLYSACCHARIDES
    Publication number: 20160145311
    Abstract: Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
    Type: Application
    Filed: February 1, 2016
    Publication date: May 26, 2016
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., CollPlant Ltd.
    Inventors: Oded SHOSEYOV, Shaul LAPIDOT, Sigal MEIROVITCH, Daniel L. SIEGEL
  • Compositions comprising fibrous polypeptides and polysaccharides
    Patent number: 9273152
    Abstract: Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: March 1, 2016
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., CollPlant Ltd.
    Inventors: Oded Shoseyov, Shaul Lapidot, Sigal Meirovitch, Daniel L Siegel
  • METHODS OF GENERATING AND USING PROCOLLAGEN
    Publication number: 20150328288
    Abstract: A method of promoting wound healing, treating fibrosis and/or promoting angiogenesis is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of a procollagen, thereby promoting wound healing, treating fibrosis and/or promoting angiogenesis in the subject.
    Type: Application
    Filed: August 3, 2015
    Publication date: November 19, 2015
    Applicant: CollPlant Ltd.
    Inventors: Oded SHOSEYOV, Or Dgany, Daniel L Siegel
  • Compositions comprising fibrous polypeptides and polysaccharides
    Patent number: 9145463
    Abstract: Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 29, 2015
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., CollPlant Ltd.
    Inventors: Oded Shoseyov, Shaul Lapidot, Sigal Meirovitch, Daniel L. Siegel
  • Methods of generating and using procollagen
    Patent number: 9095569
    Abstract: A method of promoting wound healing, treating fibrosis and/or promoting angiogenesis is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of a procollagen, thereby promoting wound healing, treating fibrosis and/or promoting angiogenesis in the subject.
    Type: Grant
    Filed: April 16, 2009
    Date of Patent: August 4, 2015
    Assignee: CollPlant Ltd.
    Inventors: Oded Shoseyov, Or Dgany, Daniel L. Siegel
  • COMPOSITIONS COMPRISING FIBROUS POLYPEPTIDES AND POLYSACCHARIDES
    Publication number: 20150094452
    Abstract: Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
    Type: Application
    Filed: December 8, 2014
    Publication date: April 2, 2015
    Inventors: Oded SHOSEYOV, Shaul Lapidot, Sigal Meirovitch, Daniel L Siegel
  • Compositions comprising fibrous polypeptides and polysaccharides
    Patent number: 8906651
    Abstract: Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: December 9, 2014
    Assignee: CollPlant Ltd.
    Inventors: Oded Shoseyov, Shaul Lapidot, Sigal Meirovitch, Daniel L. Siegel
  • COMPOSITIONS COMPRISING FIBROUS POLYPEPTIDES AND POLYSACCHARIDES
    Publication number: 20140256641
    Abstract: Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 11, 2014
    Applicants: CollPlant Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Oded SHOSEYOV, Shaul Lapidot, Sigal Meirovitch, Daniel L. Siegel
  • Compositions comprising fibrous polypeptides and polysaccharides
    Patent number: 8431158
    Abstract: Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: April 30, 2013
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., CollPlant Ltd.
    Inventors: Oded Shoseyov, Shaul Lapidot, Sigal Meirovitch, Daniel L. Siegel
  • METHODS OF GENERATING AND USING PROCOLLAGEN
    Publication number: 20110269667
    Abstract: A method of promoting wound healing, treating fibrosis and/or promoting angiogenesis is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of a procollagen, thereby promoting wound healing, treating fibrosis and/or promoting angiogenesis in the subject.
    Type: Application
    Filed: April 16, 2009
    Publication date: November 3, 2011
    Inventors: Oded Shoseyov, Or Dgany, Daniel L. Siegel
  • COMPOSITIONS COMPRISING FIBROUS POLYPEPTIDES AND POLYSACCHARIDES
    Publication number: 20100317588
    Abstract: Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
    Type: Application
    Filed: November 26, 2008
    Publication date: December 16, 2010
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., CollPlant Ltd.
    Inventors: Oded Shoseyov, Shaul Lapidot, Sigal Meirovitch, Daniel L. Siegel
  • Method of producing recombinant ?-glucosidase and an aroma spreading plant
    Patent number: 7223902
    Abstract: The invention provides a method of producing a recombinant polypeptide having ?-glucosidase enzymatic activity, a polynucleotide encoding the polypeptide, nucleic acid constructs carrying the polynucleotide, transformed cells, such as yeast cells, and transgenic organisms expressing the polynucleotide. The invention provides various uses of the polypeptide, the polynucleotide, cells and/or organisms, including producing a recombinant polypeptide having ?-glucosidase enzymatic activity, increasing the level of aromatic compounds in alcoholic beverages, as well as other fermentation products of plant material, hydrolyzing cellobiose and thus increasing the level of fermentable glucose, increasing the production of alcohol; such as ethanol from plant material, increasing the aroma released from a plant, or a plant, product, and hydrolysis or transglycosylation of glycosides.
    Type: Grant
    Filed: November 15, 2000
    Date of Patent: May 29, 2007
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Wei Shu, Ira Marton, Daniel L. Siegel, Bravdo Ben-Ami, Mara Dekel, Oded Shoseyov
  • Method of releasing solid matrix affinity adsorbed particulates
    Patent number: 6184011
    Abstract: A method of releasing particulates from a solid matrix is provided. The method is effected adding to the solid matrix a degrading enzyme capable of degrading the solid matrix, to thereby release the particulates from the solid matrix.
    Type: Grant
    Filed: March 22, 1999
    Date of Patent: February 6, 2001
    Assignees: CBD Technologies, LTD, Yissum R&D Company of the Hebrew University
    Inventors: Daniel L. Siegel, Oded Shoseyov