Abstract: Embodiments in accordance with the present invention relate to a platform facilitating different drug development software programs. In one embodiment, the integrated software platform includes a graphical environment for creating, storing, and manipulating workflows. The workflows depict operations that are to be performed by certain functional objects, and the flow of information between those objects. One example of an object is a model of drug behavior, disposition, and/or physiological response to drug activity, and certain embodiments allow for the graphical creation and editing of such a model. Other embodiments provide a user with the ability to easily overlay model predicted valves with observed data.

Abstract: Apparatus and methods for controlling the administration of intravenous drugs for sedation of a patient. Safe and controlled levels of sedation are provided by the use of a system for continous monitoring of patient pulse oximetry levels during the sedative's adminstration. Adequate levels of sedation that are clinically desirable are accomplished by the device, safely and smoothly, without the risk of respiratory depression. Preestablished oximetry ranges are provided before and/or during administration of the analgesic as the maximum and minimum acceptable saturation levels. Levels of sedation are continuously adjusted in response to increases or drops in oxygen saturation to smoothly maintain the saturation levels within the preestablished parameters.