Patents by Inventor Daniel Lafontaine

Daniel Lafontaine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9993491
    Abstract: The present invention includes novel compounds and pharmaceutically acceptable formulations of said compounds which exhibit antibiotic activity against microorganisms bearing a guanine riboswitch that controls the expression of the guaA gene, including organisms which are resistant to certain antibiotic families, and which are useful as antibacterial agents for treatment or prophylaxis of bacterial infections in animals or in humans, in particular but not limited to infections of the mammary gland, or their use as antiseptics, agents for sterilization or disinfection.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: June 12, 2018
    Assignee: SOCPRA—SCIENCES ET GÉNIE S.E.C.
    Inventors: Jerome Mulhbacher, Daniel Lafontaine, Francois Malouin, Marianne Allard, Eric Marsault
  • Patent number: 9861473
    Abstract: A cardiac valve with a first anchor frame and a cover on the first anchor frame for unidirectional flow of a liquid through the valve.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: January 9, 2018
    Assignee: Boston Scientific Scimed Inc.
    Inventor: Daniel Lafontaine
  • Patent number: 9157002
    Abstract: A process for preparing a pigment dispersion including melting a phase change ink carrier and an optional dispersant at a temperature of from about 100° C. to about 170° C. in a jacketed vessel comprising a jacket surrounding an immersion mill or basket mill attachment and a dispersion blade attachment disposed within the jacketed vessel; mixing the melted phase change ink carrier and optional dispersant with a dispersion blade in the jacketed vessel; adding a pigment to the melted, mixed phase change ink carrier and optional dispersant in the jacketed vessel; wetting the pigment; after pigment wetting, reducing the pigment particle size using an immersion mill or basket mill attachment in the jacketed vessel; and discharging the pigment dispersion.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: October 13, 2015
    Assignee: Xerox Corporation
    Inventors: Karina Lopez, Enno Eric Agur, Santiago Faucher, Frank Ping-Hay Lee, Aurelian Valeriu Magdalinis, Biby Esther Abraham, Daniel Lafontaine, Jonathan Lisk
  • Publication number: 20150150890
    Abstract: The present invention includes novel compounds and pharmaceutically acceptable formulations of said compounds which exhibit antibiotic activity against microorganisms bearing a guanine riboswitch that controls the expression of the guaA gene, including organisms which are resistant to certain antibiotic families, and which are useful as antibacterial agents for treatment or prophylaxis of bacterial infections in animals or in humans, in particular but not limited to infections of the mammary gland, or their use as antiseptics, agents for sterilization or disinfection.
    Type: Application
    Filed: February 6, 2015
    Publication date: June 4, 2015
    Inventors: JEROME MULHBACHER, DANIEL LAFONTAINE, FRANCOIS MALOUIN, MARIANNE ALLARD, ERIC MARSAULT
  • Publication number: 20150013567
    Abstract: A process for preparing a pigment dispersion including melting a phase change ink carrier and an optional dispersant at a temperature of from about 100° C. to about 170° C. in a jacketed vessel comprising a jacket surrounding an immersion mill or basket mill attachment and a dispersion blade attachment disposed within the jacketed vessel; mixing the melted phase change ink carrier and optional dispersant with a dispersion blade in the jacketed vessel; adding a pigment to the melted, mixed phase change ink carrier and optional dispersant in the jacketed vessel; wetting the pigment; after pigment wetting, reducing the pigment particle size using an immersion mill or basket mill attachment in the jacketed vessel; and discharging the pigment dispersion.
    Type: Application
    Filed: July 12, 2013
    Publication date: January 15, 2015
    Inventors: Karina Lopez, Enno Eric Agur, Santiago Faucher, Frank Ping-Hay Lee, Aurelian Valeriu Magdalinis, Biby Esther Abraham, Daniel Lafontaine, Jonathan Lisk
  • Publication number: 20140094645
    Abstract: The various embodiments disclosed herein relate to percutaneous interface lines and related methods for implanting such lines. Each percutaneous interface line has an internal component coupleable to a percutaneous component with an internal connector. The percutaneous component can have a Y-shaped end having two arms, one arm having a lumen and another arm having at least one wire. The methods for implanting a percutaneous interface line include the use of a tunneling tool having a flexible rod and a replaceable dilator tip.
    Type: Application
    Filed: March 13, 2013
    Publication date: April 3, 2014
    Applicant: Sunshine Heart Company Pty LTD
    Inventors: Daniel Lafontaine, William Peters, Martin Cook, Tolga Tas
  • Publication number: 20140081390
    Abstract: A cardiac valve with a support frame having a first end member and a second end member opposing the first end member in a substantially fixed distance relationship, and a cover extending over the support frame to allow for unidirectional flow of a liquid through the valve.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 20, 2014
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: Mark L. Jenson, William J. Drasler, Daniel Lafontaine
  • Publication number: 20130345799
    Abstract: A cardiac valve with a first anchor frame and a cover on the first anchor frame for unidirectional flow of a liquid through the valve.
    Type: Application
    Filed: August 19, 2013
    Publication date: December 26, 2013
    Applicant: Boston Scientific Scimed, Inc.
    Inventor: Daniel Lafontaine
  • Patent number: 8282599
    Abstract: A catheter device having a proboscis, such as a needle, and a transducer which detects the axial displacement of the proboscis in relation to the distal tip of the catheter. The transducer is positioned at a distal portion of the catheter and may comprise an induction coil or a potentiometer. Axial displacement of the proboscis changes the amount of inductance or resistance in the transducer. This change in inductance or resistance can be calibrated to the amount of axial displacement of the proboscis and provided as feedback to the user.
    Type: Grant
    Filed: November 16, 2007
    Date of Patent: October 9, 2012
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Alan Eskuri, Daniel Lafontaine
  • Publication number: 20120122819
    Abstract: The present invention includes novel compounds and pharmaceutically acceptable formulations of said compounds which exhibit antibiotic activity against microorganisms bearing a guanine riboswitch that controls the expression of the guaA gene, including organisms which are resistant to certain antibiotic families, and which are useful as antibacterial agents for treatment or prophylaxis of bacterial infections in animals or in humans, in particular but not limited to infections of the mammary gland, or their use as antiseptics, agents for sterilization or disinfection.
    Type: Application
    Filed: June 14, 2010
    Publication date: May 17, 2012
    Applicant: SOCPRA - SCIENCES ET GENIE S.E.C.
    Inventors: Jérôme Mulhbacher, Daniel Lafontaine, François Malouin, Marianne Allard, Eric Marsault
  • Publication number: 20080314394
    Abstract: Devices and methods for creating a series of percutaneous myocardial revascularization (PMR) channels in the heart. One method includes forming a pattern of channels in the myocardium leading from healthy tissue to hibernating tissue. Suitable channel patterns include lines and arrays. One method includes anchoring a radiopaque marker to a position in the ventricle wall, then using fluoroscopy repeatedly to guide positioning of a cutting tip in the formation of multiple channels. Another method uses radiopaque material injected into each channel formed, as a marker. Yet another method utilizes an anchorable, rotatable cutting probe for channel formation about an anchor member, where the cutting probe can vary in radial distance from the anchor. Still another method utilizes a multiple wire radio frequency burning probe, for formation of multiple channels simultaneously. Still another method utilizes liquid nitrogen to cause localized tissue death.
    Type: Application
    Filed: July 28, 2005
    Publication date: December 25, 2008
    Inventors: Louis Ellis, Daniel Lafontaine, Roger Hastings, Lauri DeVore
  • Publication number: 20080140006
    Abstract: A catheter device having a proboscis, such as a needle, and a transducer which detects the axial displacement of the proboscis in relation to the distal tip of the catheter. The transducer is positioned at a distal portion of the catheter and may comprise an induction coil or a potentiometer. Axial displacement of the proboscis changes the amount of inductance or resistance in the transducer. This change in inductance or resistance can be calibrated to the amount of axial displacement of the proboscis and provided as feedback to the user.
    Type: Application
    Filed: November 16, 2007
    Publication date: June 12, 2008
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Alan Eskuri, Daniel Lafontaine
  • Publication number: 20070250050
    Abstract: Devices and methods for cooling vessel walls to inhibit restenosis in conjunction with medical procedures such as coronary artery angioplasty. Stenosed vessel walls can be cooled prior to angioplasty, after angioplasty, or both. The invention is believed to inhibit restenosis through cooling to a temperature near freezing, preferably without causing substantial vessel wall cell death. One catheter device includes a distal tube region having coolant delivery holes radially and longitudinally distributed along the distal region. In some devices, holes spray coolant directly onto the vessel walls, with the coolant absorbed into the blood stream. In other embodiments, a balloon or envelope is interposed between the coolant and the vessel walls and the coolant returned out of the catheter through a coolant return lumen. Some direct spray devices include an occlusion device to restrict blood now past the region being cooled. Pressure, temperature, and ultrasonic probes are included in some cooling catheters.
    Type: Application
    Filed: April 12, 2007
    Publication date: October 25, 2007
    Inventor: Daniel LAFONTAINE
  • Publication number: 20070150037
    Abstract: Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrodes that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Each of the electrodes contains a source of electrical energy for pacing the myocardium and is adapted to receive electromagnetic energy from a source outside the myocardium. The system also includes a source adapted for placement outside the myocardium and that uses locally measured electrocardiograms to synchronize pacing of the heart by sending electromagnetic commands to the electrodes to pace the myocardium surrounding the electrodes. Also disclosed is various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.
    Type: Application
    Filed: March 8, 2007
    Publication date: June 28, 2007
    Inventors: Roger Hastings, William Drasler, Daniel Lafontaine, Anupama Sadasiva, Scott Smith
  • Publication number: 20070150038
    Abstract: Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrodes that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Each of the electrodes contains a source of electrical energy for pacing the myocardium and is adapted to receive electromagnetic energy from a source outside the myocardium. The system also includes a source adapted for placement outside the myocardium and that uses locally measured electrocardiograms to synchronize pacing of the heart by sending electromagnetic commands to the electrodes to pace the myocardium surrounding the electrodes. Also disclosed is various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.
    Type: Application
    Filed: March 8, 2007
    Publication date: June 28, 2007
    Inventors: Roger Hastings, William Drasler, Daniel Lafontaine, Anupama Sadasiva, Scott Smith
  • Publication number: 20070150009
    Abstract: Apparatus, system, and method that include a pacing apparatus having a stent electrode through which pulses of electrical current can be delivered. Stent electrodes receive energy for generating the electrical current from a variety of sources. Sources include from one or more induction coils that can form at least a portion of the stent. Sources can also include an implantable pulse generator coupled to a lead through which pulses of the electrical current are supplied to the stent electrodes.
    Type: Application
    Filed: December 22, 2005
    Publication date: June 28, 2007
    Inventors: Graig Kveen, Roger Hastings, Anupama Sadasiva, Vitaly Shapovalov, Daniel Lafontaine
  • Publication number: 20070135883
    Abstract: Some embodiments of pacing systems employ wireless electrode assemblies to provide pacing therapy. The wireless electrode assemblies may wirelessly receive energy via an inductive coupling so as to provide electrical stimulation to the surrounding heart tissue. In certain embodiments, the wireless electrode assembly may include one or more biased tines that shift from a first position to a second position to secure the wireless electrode assembly into the inner wall of the heart chamber.
    Type: Application
    Filed: October 13, 2006
    Publication date: June 14, 2007
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: William Drasler, Michael Pikus, Roger Hastings, Scott Smith, Martin Willard, Daniel Lafontaine, Douglas Saholt, Graig Kveen
  • Patent number: 7148044
    Abstract: A method is described for cleaving a nucleic acid substrate with a nucleic acid enzyme at a cleavage site comprising mixing the substrate with the enzyme, wherein the substrate includes a 7 nucleotide sequence with at least 6 nucleotides 3? to the cleavage site and at least 1 nucleotide 5? to the cleavage site and of formula: 5?-H?GNNHNN-3? wherein each N is a nucleotide which may be the same or different, H is a nucleotide selected from the group consisting of A, U, C, and T, and is the site of cleavage, and H? is a ribonucleotide selected from the group consisting of A, U, and C, wherein (i) the first nucleotide 3? to the cleavage site is capable of forming a wobble pair with the enzyme, (ii) the second, third, fifth, and sixth nucleotides 3? to the cleavage site are capable of forming conventional Watson-Crick base pairs with the enzyme, (iii) the fourth nucleotide 3? to the cleavage site is capable of forming a non-conventional Watson-Crick base pair with the enzyme, and (iv) the first nucleotide 5? to
    Type: Grant
    Filed: October 30, 2000
    Date of Patent: December 12, 2006
    Assignee: Universite de Sherbrooke
    Inventors: Jean-Pierre Perreault, Sirinart Ananvoranich, Daniel Lafontaine
  • Publication number: 20060235509
    Abstract: A cardiac valve with a first anchor frame and a cover on the first anchor frame for unidirectional flow of a liquid through the valve.
    Type: Application
    Filed: April 15, 2005
    Publication date: October 19, 2006
    Inventor: Daniel Lafontaine
  • Publication number: 20060212027
    Abstract: Some embodiments of the invention relate to a system for treating tissue internal to a body, such as heart tissue. For example, the system may be used to ablate tissue as a treatment for atrial fibrillation. In certain embodiments, the system is capable of causing scar tissue to form in ostial areas of the atrium rather than inside the pulmonary vein. In such embodiments, the system may include a tissue treatment member that is operable to form an annular area of ablated tissue along the outer portion of the ostium in an area known as the antrum.
    Type: Application
    Filed: March 17, 2005
    Publication date: September 21, 2006
    Inventors: Nassir Marrouche, Daniel Lafontaine