Abstract: The present invention relates to a method for determining a vehicle operator's visual input of an object in the operator's surroundings, which method comprises receiving an object position signal indicative of the position of at least one object, receiving an operator motion input signal indicative of operator physiological data comprising information relating to body motion of the operator, estimating an operator eye-gaze direction, and determining a visual input quality value representative of level of visual input of the at least one object received by the operator, based on the object position signal and the estimated operator eye-gaze direction.

Abstract: The present invention generally relates to a method for improving the reliability of a portion of physiological data from an image sensor monitoring an operator positioned in an operator compartment of a vehicle. An embodiment of the method includes receiving, from the image sensor, physiological data including information relating to at least one of eye, face, head, arms and body motion of the operator, identifying an indication of at least an eyelid closure, eye movement or head movement of the operator based on the physiological data; comparing at least one of the physiological data and a lighting condition within the operator compartment with a set of rules for a current operator status; and classifying the type of eyelid closure, eye movement and/or head movement by correlating the identified eyelid closure, eye movement and/or head movement and a result of the comparison.

Abstract: The present invention generally relates to a method, a system and/or a computer readable program. An embodiment of the method includes acquiring an input signal indicative of the operator's expectation of the state of the object at a first point in time; determining a state of the object at a second later point in time based on the input signal; acquiring an input signal indicative of an estimated visual input of the operator at the second point in time; determining the operator's expectation of the state at the second point in time, based on the operator's expectation of the state of the object at the first point in time, and the estimated visual input and the state of the object at the second point in time; and providing an output signal indicative of the operator's expectation of the state at the second point in time.

Abstract: A system and method for determining a speed profile for a vehicle travelling along a road in which a curve speed estimation unit receives inputs indicating a position of the vehicle relative to a curve ahead of the vehicle, and inputs related to vehicle velocity, curve geometry, road surface conditions, vehicle-specific data; and driver preferences. The curve sped estimation unit use at least some of the above-listed inputs to determine a speed profile for the curve by generating an acceleration limit map which depends on a relationship between a maximum possible longitudinal acceleration and a maximum possible lateral acceleration.

Abstract: The present invention relates to the preparation of compositions comprising benzoyl peroxide, with or without other additional active ingredients. The process involves introducing benzoyl peroxide, along with any other active ingredients present, into a fatty substance that contains and protects the ingredients that would otherwise be unstable when in contact with one another. The composition is designed to allow all ingredients to become available for skin contact or skin absorption when the fatty substance softens and/or melts as the composition is applied to the skin. The benzoyl peroxide may be pre-micronized to a particle distribution size of about d90 of 0.1 to 150 microns, preferably d90 of 10 to 15 microns.

Abstract: The present invention provides a process for purifying a monoterpene or sesquiterpene having a purity greater than about 98.5% (w/w). The process comprises the steps of derivatizing the monoterpene (or sesquiterpene) to produce a monoterpene (or sesquiterpene) derivative, separating the monoterpene (or sesquiterpene) derivative, and releasing the monoterpene (or sesquiterpene) from the derivative. Also encompassed by the scope of the present invention is a pharmaceutical composition comprising a monoterpene (or sesquiterpene) having a purity greater than about 98.5% (w/w). The purified monoterpene can be used to treat a disease such as cancer. The present monoterpene (or sesquiterpene) may be administered alone, or may be co-administered with radiation or other therapeutic agents, such as chemotherapeutic agents.

Abstract: The present invention includes methods/processes and intermediates for preparing compounds having structural Formula (I): wherein X is alkyl, substituted alkyl, alkenyl, substituted alkenyl, heteroalkyl, substituted heteroalkyl, heteroalkenyl, or substituted heteroalkenyl.

Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.

Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.

Abstract: Disclosed herein are processes for preparing aqueous ?-hydroxybutyrate having a pH of about 8 or less (upon reaching equilibrium). The disclosed processes include both continuous processes and batch processes wherein the ratio of reactants is controlled to provide the product at the desired pH.

Abstract: The present invention is directed to a process for the preparation of the saponification products of lactones, preferably three- to eight-membered lactones. The present invention is also directed to a process for the preparation of compounds having general formula (I): wherein M is selected from the group consisting of cationic species, preferably metal cations (even more preferably Na), from a compound having the formula (II): comprising reacting a compound having formula (II) with a suitable hydroxide salt (M-OH) (III) such as, preferably, sodium hydroxide, in an aqueous medium. The reaction preferably utilizes a continuous process method for the substantial consumption of reagent and continuous, semi-continuous, and/or batch-wise processing for final consumption of reagent.

Abstract: An object awareness determination system includes an external object sensor system to sense objects and generate input data relating to the objects external to a host vehicle, wherein the input data includes an object position (x, y), an object velocity |({dot over (x)}, {dot over (y)})| and an object direction of movement (({dot over (x)}, {dot over (y)})/|({dot over (x)}, {dot over (y)})|) associated with each object in said detecting range. Additionally, the system includes a controller for determining awareness of the user to an object that recently entered the detecting range of the external object sensor system, and a method for determining awareness of the object.

Abstract: A method of preparing metal mesoporphyrin halide compounds is described. The metal mesoporphyrin halide compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to the metal mesoporphyrin halide through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery.

Abstract: An active safety system for a vehicle includes an external object sensor system arranged on a host vehicle. The sensor system designed to sense objects external to the host vehicle and generate input data relating to the objects, wherein the input data includes an object position ((R, ?rel)(t)). Additionally, a threat indicator is included to assign a threat level (Tk(t)) to each external object (k) detected by the sensor system.

Abstract: The present invention is directed to a processes for the synthesis of trans isomer of 4,6-disubstituted-tetrahydro-furo, thieno, pyrrolo and cyclopenta-[3,4][1,3]dioxoles (Formula I). The process comprises the steps of: (a) obtaining a compound of Formula II, which is a mixture of cis and trans-diastereomers, and (b) chemically decomposing the compound of Formula II in a solution comprising a solvent and an acid that is a hydrogen donor or an electron pair acceptor, whereby the cis diastereomer is decomposed and the compound of Formula I is obtained. The compounds prepared by the present invention are useful in treating diseases or conditions associated with platelet aggregation and/or platelet activation.

Abstract: A non-contact support platform for supporting without contact a stationary or traveling object by air-cushion induced forces, the platform comprising at least one of two substantially opposite support surfaces, each support surfaces comprising at least one of a plurality of basic cells each having at least one of a plurality of pressure outlets and at least one of a plurality of air-evacuation channels at least one of a plurality of outlets, and one of a plurality of air-evacuation channels, each of the pressure outlets fluidically connected through a pressure flow restrictor to a high-pressure reservoir, the pressure outlets providing pressurized air for generating pressure induced forces, maintaining an air-cushion between the object and the support surface, the pressure flow restrictor characteristically exhibiting fluidic return spring behavior; each of said at least one of a plurality of air-evacuation channels having an inlet and outlet, the inlet kept at an ambient pressure or lower, under vacuum condi

Abstract: Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions.

Abstract: An object awareness determination system includes an external object sensor system to sense objects and generate input data relating to the objects external to a host vehicle, wherein the input data includes an object position (x, y), an object velocity |({dot over (x)}, {dot over (y)})| and an object direction of movement (({dot over (x)}, {dot over (y)})/|({dot over (x)}, {dot over (y)})|) associated with each object in said detecting range. Additionally, the system includes a controller for determining awareness of the user to an object that recently entered the detecting range of the external object sensor system, and a method for determining awareness of the object.

Abstract: An active safety system for a vehicle includes an external object sensor system arranged on a host vehicle. The sensor system designed to sense objects external to the host vehicle and generate input data relating to the objects, wherein the input data includes an object position ((R, ?rel)(t)). Additionally, a threat indicator is included to assign a threat level (Tk(t)) to each external object (k) detected by the sensor system.

Abstract: The present invention is directed to a processes for the synthesis of trans isomer of 4,6-disubstituted-tetrahydro-furo, thieno, pyrrolo and cyclopenta-[3,4][1,3]dioxoles (Formula I). The process comprises the steps of: (a) obtaining a compound of Formula II, which is a mixture of cis and trans-diastereomers, and (b) chemically decomposing the compound of Formula II in a solution comprising a solvent and an acid that is a hydrogen donor or an electron pair acceptor, whereby the cis diastereomer is decomposed and the compound of Formula I is obtained. The compounds prepared by the present invention are useful in treating diseases or conditions associated with platelet aggregation and/or platelet activation.