Abstract: The present disclosure relates to antibodies and antibody conjugates that selectively bind to tissue factor and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies and antibody conjugates, such as therapeutic and diagnostic methods.

Abstract: A system and a method include a heating layer including perforations extending from a first surface to a second surface opposite from the first surface. The perforations provide acoustic paths. The heating layer is configured to provide electrically resistive heating to a component. An acoustic layer can be coupled to the heating layer. The perforations extend to the acoustic layer.

Abstract: A device for maintaining an optical path of an optical imaging system free of fog includes an elongated member having a distal end and a proximal end, a near-infrared (NIR) light-absorbing optical window disposed at the distal end, and an optical system disposed along the optical path. The device also includes a coupling module coupled to the elongated member at the proximal end and configured to transmit near-infrared light to the NIR light-absorbing optical window along the optical path and receive a light beam from an area of interest along the optical path.

Abstract: A coil structure for near-field wireless power transfer, integrating the traditional inductor and external capacitor structure into one single coil and forming a series resonance. The series resonance is achieved by a terminal connection and layering method. The electric field is canceled via a distributed turn-to-turn interleaving structure. With the integrated capacitor, the costs and space of a resonant capacitor can be saved. With the canceled electric field, the interference with neighboring components, such as touch-screen, can be reduced. Other benefits can include low-profile and fabrication convenience based on RGB technology. This coil can be useful for both consumer electronics and electric vehicle wireless charging.

Abstract: Provided herein are antibodies, or antigen binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen binding portions thereof.

Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Abstract: A locking structure of a Bowens mount, configured to lock a luminaire with an optical accessory having a Bowens mount, including a rotating member and a mount provided on a luminaire front housing, in which the mount is provided on a peripheral side of a light outlet aperture of the luminaire front housing, the rotating member is threaded to the mount, the mount includes three grooves fitted with protrusions of the Bowens mount, a height of each groove is lower than that of each protrusion of the Bowens mount, and the rotating member includes notch parts corresponding to at least three grooves.

Abstract: An IC die package includes a substrate comprising glass and a plurality of holes extending through the glass. A via metallization is present within the holes. A liner is between the via metallization and the glass. The liner can comprise a beta-titanium alloy layer, polymer hydrogel layer and an MXene seed layer, an organic material layer and a metal layer, or an organic material layer between first and second metal layers. A polymer layer may be formed by electrodeposition of charged nanoparticles.

Abstract: The techniques described herein relate to methods and systems for three-dimensional (3D) inspection using deep learning model pre-trained with two-dimensional (2D) images. The techniques include transforming a 3D representation (e.g., captured 3D point cloud, 3D profiles, meshes, voxels) to a 2D map, which can be input to a deep learning model pre-trained with 2D images. The 2D map includes elements disposed in an array. Each element includes a vector of a number of geometric features. Such a configuration enables the 2D map to be in a structure acceptable by the 2D deep learning model. The 2D deep learning model generates an output based on the 2D map and provides the output to a subsystem for generating an inspection result. The inspection result can have a 3D result such as a surface area and/or volume.

Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).

Abstract: Embodiments presented provide for modeling of wireline runs for hydrocarbon recovery operations. In embodiments, a run duration of wireline activities is split into a winch duration and a pass duration, wherein the pass duration is calculated using a machine learning model.

Abstract: Photoresist rework of metal-containing photoresist is disclosed. Rework can be accomplished using a thermal process by exposing a substrate to an elevated temperature and an etch gas. Rework can be also accomplished using a wet process by exposing the substrate to an inorganic acidic solution. Residue or other contaminants may be cleaned up from the substrate after rework by exposure to high temperatures, plasma, or wet clean.

Abstract: An optical fiber that includes a silica core and a cladding surrounding the core is disclosed, the optical fiber having a low attenuation. In embodiments, the optical fiber has an attenuation at 1550 nm of about 0.1420 dB/km. Furthermore, the diameter of the core may be larger than a fundamental mode field diameter of the optical fiber at a wavelength of 1550 nm. In embodiments, the core is doped with an alkali dopant.

Abstract: A prophy angle with a splatter guard. The splatter guard is provided in the form of a partial cylinder extending along the side of the prophy cup.

Abstract: A method for selectively depositing graphene on cobalt caps on copper interconnects for dual damascene structures in a back-end-of-line substrate is provided. The method comprises providing a semiconductor substrate comprising a first dielectric layer, the copper interconnect in the first dielectric layer, and the cobalt cap on the copper interconnect, the cobalt cap having an exposed metal surface, wherein the exposed metal surface comprises cobalt, and selectively depositing carbon layer on the exposed metal surface.

Abstract: A query that includes one or more variables is received. The one or more variables correspond to one or more interactive elements. A large language model is utilized to generate a query response that associates one or more variables included in the query to the one or more interactive elements. A script is generated utilizing the query response that associates the one or more variables included in the query to the one or more interactive elements.

Abstract: An online concierge system compensates pickers who fulfill orders including one or more items based in part on weights of the items included in an order. Because the online concierge system does not physically possess the items that are obtained, the online concierge system cannot directly weigh the items and weights specified for items in a catalog from a retailer may be inaccurate. To more accurately determine weights of items, the online concierge system trains a weight prediction model to estimate an item's weight from attributes of the item and uses the output of the weight prediction model to determine compensation to a picker. The weight prediction model may output a predicted weight of an item or a classification of the item as heavy or light. Where discrepancies are found between a predicted weight and the catalog weight of an item, additional information about the item is obtained.

Abstract: The present disclosure relates to RNAi agents, e.g., double stranded RNAi agents such as siRNAs, able to Inhibin Subunit Beta E (INHBE) gene expression. Also disclosed are pharmaceutical compositions that include INHBE RNAi agents and methods of use thereof. The INHBE RNAi agents disclosed herein may be conjugated to targeting ligands to facilitate the delivery to cells, including to hepatocytes. Delivery of the INHBE RNAi agents in vivo provides for inhibition of INHBE gene expression. The RNAi agents can be used in methods of treatment of diseases, disorders, or symptoms mediated in part by INHBE gene expression, such as obesity, diabetes, liver inflammation, dyslipidemia, or metabolic disease.

Abstract: Provided herein are lipid compounds of Formulae (I) and (II), and pharmaceutically acceptable salts, co-crystals, tautomers, stereoisomers, solvates, hydrates, polymorphs, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive lipid compounds, compositions, or formulations for treating and/or preventing diseases (e.g., genetic disease, proliferative disease, hematological disease, neurological disease, painful condition, psychiatric disorder, metabolic disorder, long-term medical condition, inflammatory disease, autoinflammatory disease, liver disease, lung disease, spleen disease, familial amyloid neuropathy, cardiovascular disease, viral infection, infectious disease, fibrotic condition, or autoimmune disease) in a subject, methods for synthesizing the compounds described herein, and compounds described herein synthesized by the synthetic methods described herein.

Abstract: A query that includes one or more variables is received. The one or more variables correspond to one or more interactive elements. A large language model is utilized to generate a query response that associates one or more variables included in the query to the one or more interactive elements. A script is generated utilizing the query response that associates the one or more variables included in the query to the one or more interactive elements.