Abstract: A method for friction stir forming a metal matrix composite (MMC) structure (76). The method includes the step of providing a substrate (12) comprising a metallic material and securing a preformed MMC layer (14, 16) comprising an MMC material in a position overlying at least a portion of the substrate (12). The method further includes the step of friction stirring the preformed MMC layer (14, 16) with a friction stirring tool (50) which includes a rotating probe (56), including locating the probe (56) at a stirring depth at which the probe (56) extends through the preformed MMC layer (14, 16) into a portion of the substrate (12) and passing the tool (50) through the preformed MMC layer (14) at the stirring depth to friction stir the preformed MMC layer (14, 16) and integrate the preformed MMC layer (14, 16) with the substrate (12).

Abstract: A method for friction stir forming a metal matrix composite (MMC) structure (76). The method includes the step of providing a substrate (12) comprising a metallic material and securing a preformed MMC layer (14, 16) comprising an MMC material in a position overlying at least a portion of the substrate (12). The method further includes the step of friction stirring the preformed MMC layer (14, 16) with a friction stirring tool (50) which includes a rotating probe (56), including locating the probe (56) at a stirring depth at which the probe (56) extends through the preformed MMC layer (14, 16) into a portion of the substrate (12) and passing the tool (50) through the preformed MMC layer (14) at the stirring depth to friction stir the preformed MMC layer (14, 16) and integrate the preformed MMC layer (14, 16) with the substrate (12).

Abstract: A method for producing a metal structure comprising a porous inter-dendritic matrix defining a network of dendritic channels, the method comprising the steps of: preparing an alloy melt comprising a metal element and at least one alloying element, cooling the alloy melt to a solid alloy, wherein the cooling promotes formation of a network of dendrites rich in the at least one alloying element within an inter-dendritic matrix rich in the metal, dealloying the solid alloy to remove alloying element from the dendrites and the inter-dendritic matrix to obtain the metal structure.

Abstract: An improved magnesium-based alloy for wrought applications is disclosed, including a method of fabricating alloy sheet from said alloy. The improved magnesium-based alloy consists of: 0.5 to 4.0% by weight zinc; 0.02 to 0.70% by weight a rare earth element, or mixture of the same including gadolinium; and incidental impurities. The rare earth element in some embodiments may be yttrium and/or gadolinium. In some embodiments the magnesium-based alloy may also consist of a grain refiner and in some embodiments the grain refiner may be zirconium. In combination, the inclusion of zinc and a rare earth element, into the magnesium alloy may have enhanced capacity for rolling workability, deep drawing at low temperatures and stretch formability at room temperature. The improved alloy may also exhibit increased tensile strength and formability while evincing a reduced tendency for tearing during preparation.

Abstract: The present disclosure provides an automated bioprocessing device, which may comprises a processing machine, one or more removable washing cartridges. The removable washing cartridge may comprise a shell, a sample holder, a washing basin, a waste container, a reagent container, a rotation mechanism, and a poking mechanism. The processing machine may comprise a motor, which may provide power to the inserted removable washing cartridge.

Abstract: The present disclosure is directed to peptide-based compounds, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The compounds and compositions of the present disclosure may inhibit neurotransmitter release and muscle contraction as a treatment for wrinkles. The compounds of the disclosure may be used for pathological neuronal exocytosis-mediated cosmetic and/or therapeutic purposes.

Abstract: The present disclosure provides an automated bioprocessing device, which may comprises a processing machine, one or more removable washing cartridges. The removable washing cartridge may comprise a shell, a sample holder, a washing basin, a waste container, a reagent container, a rotation mechanism, and a poking mechanism. The processing machine may comprise a motor, which may provide power to the inserted removable washing cartridge.

Abstract: The present invention provides devices, apparatuses and methods for automated processing of biological samples. This invention provides automated devices and automated methods of sequentially treating a biological sample with processing fluids in more than one washing basin. In some embodiments, the invention provides automated devices and automated methods of western blot processing. In some embodiments, the invention provides automated devices and automated methods of Southern blot processing. In some embodiments, the invention provides automated devices and automated methods of northern blot processing. In some embodiments, the invention provides automated devices and automated methods of staining biomolecules on solid supports. In some embodiments, the invention provides automated devices and automated methods of nucleic acid separation and isolation.

Abstract: The present disclosure is directed to peptide-based compounds, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The compounds and compositions of the present disclosure may inhibit neurotransmitter release and muscle contraction as a treatment for wrinkles. The compounds of the disclosure may be used for pathological neuronal exocytosis-mediated cosmetic and/or therapeutic purposes.

Abstract: The present invention provides devices, apparatuses and methods for automated processing of biological samples. This invention provides automated devices and automated methods of sequentially treating a biological sample with processing fluids in more than one washing basin. In some embodiments, the invention provides automated devices and automated methods of western blot processing. In some embodiments, the invention provides automated devices and automated methods of Southern blot processing. In some embodiments, the invention provides automated devices and automated methods of northern blot processing. In some embodiments, the invention provides automated devices and automated methods of staining biomolecules on solid supports. In some embodiments, the invention provides automated devices and automated methods of nucleic acid separation and isolation.

Abstract: An improved magnesium-based alloy for wrought applications is disclosed, including a method of fabricating alloy sheet from said alloy. The improved magnesium-based alloy consists of: 0.5 to 4.0% by weight zinc; 0.02 to 0.70% by weight a rare earth element, or mixture of the same including gadolinium; and incidental impurities. The rare earth clement in some embodiments may be yttrium and/or gadolinium. In some embodiments the magnesium-based alloy may also consist of a grain refiner and in some embodiments the grain refiner may be zirconium. In combination, the inclusion of zinc and a rare earth element, into the magnesium alloy may have enhanced capacity for rolling workability, deep drawing at low temperatures and stretch formability at room temperature. The improved alloy may also exhibit increased tensile strength and formability while evincing a reduced tendency for tearing during preparation.

Abstract: An imaging device with micro-scale optical structures comprises a plurality of display units, where each display unit comprises a plurality of micro-scale optical structures, and each micro-scale optical structure comprises a convex part, a planar part, and base part. The convex part is positioned on the base part and has an arc surface, where the arc surface comprises a left side arc face and a right side arc face for reflecting oblique incident lights from the left or the right to form a reflected light toward the front. And different arrangements of micro-scale optical structures are used for reflecting left side and right side incident lights to display different characters or images.

Abstract: A method of producing magnesium alloy strip, suitable for use in the production of magnesium alloy sheet by rolling reduction and heat treatment, involves casting magnesium alloy as strip, using a twin roll casting installation. In the casting, the thickness and temperature of the strip exiting from between rolls of the installation are controlled whereby the strip has a microstructure characterised by a primary phase having a form selected from deformed dendritic, equiaxed dendritic and a mixture of deformed and equiaxed dendritic forms. The resultant strip is amenable to production of sheet material by application of a homogenizing heat treatment followed by rolling and annealing.

Abstract: A process for the production of magnesium alloy strip, by twin roll casting, includes the steps of passing molten alloy from a source of supply to a feeding device; feeding the alloy from the feeding device through an elongate outlet of a nozzle and a pair of substantially parallel rolls spaced to define a bite therebetween; rotating said rolls whereby alloy is drawn from the chamber through the bite; and flowing coolant fluid through each roll and thereby cool alloy received in the chamber by heat energy extraction by the rolls whereby substantially complete solidification of the alloy is achieved in the chamber prior to alloy passing through the bite as hot rolled alloy strip.