Patents by Inventor Daniel LIEBER

Daniel LIEBER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic and diagnostic methods for cancer
    Patent number: 11674962
    Abstract: The present invention provides therapeutic, diagnostic, and prognostic methods for cancer. The invention provides methods of treating a cancer, methods of determining whether an individual having a cancer is likely to respond to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of predicting responsiveness of an individual having a cancer to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of selecting a therapy for an individual having a cancer, methods of providing a prognosis for an individual having a cancer, and methods of monitoring a response of an individual having a cancer, based on a blood tumor mutational burden (bTMB) score or a maximum somatic allele frequency (MSAF) from a sample (e.g., a whole blood sample, a plasma sample, a serum sample, or a combination thereof) from the individual.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: June 13, 2023
    Assignees: Genentech, Inc., Foundation Medicine, Inc.
    Inventors: Craig Anthony Cummings, Yan Li, Sarah Margaret Shagan, Erica Beth Schleifman, David Shames, David Fabrizio, Daniel Lieber, Geoffrey Alan Otto, Mark Kennedy, Travis Clark, Doron Lipson, Jie He, Shan Zhong
  • COMPOSITIONS AND METHODS FOR EVALUATING GENOMIC ALTERATIONS
    Publication number: 20200149097
    Abstract: Compositions and methods of evaluating genomic alterations in a sample are disclosed.
    Type: Application
    Filed: June 11, 2019
    Publication date: May 14, 2020
    Applicants: FOUNDATION MEDICINE, INC., FOUNDATION MEDICINE, INC.
    Inventors: Geoffrey Alan Otto, Travis Clark, Doron Lipson, Daniel Lieber, David Fabrizio
  • THERAPEUTIC AND DIAGNOSTIC METHODS FOR CANCER
    Publication number: 20190025308
    Abstract: The present invention provides therapeutic, diagnostic, and prognostic methods for cancer. The invention provides methods of treating a cancer, methods of determining whether an individual having a cancer is likely to respond to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of predicting responsiveness of an individual having a cancer to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of selecting a therapy for an individual having a cancer, methods of providing a prognosis for an individual having a cancer, and methods of monitoring a response of an individual having a cancer, based on a blood tumor mutational burden (bTMB) score or a maximum somatic allele frequency (MSAF) from a sample (e.g., a whole blood sample, a plasma sample, a serum sample, or a combination thereof) from the individual.
    Type: Application
    Filed: July 20, 2018
    Publication date: January 24, 2019
    Inventors: Craig Anthony CUMMINGS, Yan LI, Sarah Margaret PAUL, Erica Beth SCHLEIFMAN, David SHAMES, David FABRIZIO, Daniel LIEBER, Geoffrey Alan OTTO, Mark KENNEDY, Travis CLARK, Doron LIPSON, Jie HE, Shan ZHONG